X4 Pharmaceuticals (XFOR) Return on Invested Capital [ROIC] (2020 - 2026)
X4 Pharmaceuticals (XFOR) reported Return on Invested Capital [ROIC] of -36.83% for Q2 2026, up 81.89 percentage points from -118.72% a year earlier and up 1.68 percentage points from the prior quarter.
X4 Pharmaceuticals (XFOR) Return on Invested Capital [ROIC] (2020 - 2026) Analysis & Trends
For FY2025, X4 Pharmaceuticals posted Return on Invested Capital [ROIC] of -48.25%, down 12.43 percentage points from FY2024.
- Return on Invested Capital [ROIC] has a five-year change of -1.34 percentage points (FY2020 to FY2025).
- By year, Return on Invested Capital [ROIC] came in at -35.82% in FY2024 (+64.98 pp), -100.80% in FY2023 (-15.79 pp), -85.01% in FY2022 (-1.71 pp) and -83.31% in FY2021 (-36.40 pp).
- The Q2 2026 figure ranks as the highest quarterly Return on Invested Capital [ROIC] since Q1 2025.
- Year over year, Return on Invested Capital [ROIC] gained in four of the last eight quarters, with an average year-over-year change of +17.68 percentage points.
- The high point for year-over-year Return on Invested Capital [ROIC] in five years was Q1 2025 (a gain of 134.48 percentage points); the low point was Q2 2025 (a drop of 102.30 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -38.52% (Q1 2026), -43.41% (Q4 2025) and -90.94% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROIC (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | 37.16% |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | 16.10% |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | 18.68% |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | 3.56% |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | 21.95% |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | 28.83% |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | 14.33% |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -5.97% |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 13.44% |
| 10 | X4 Pharmaceuticals | 357.55 Mn | -341.13 Mn | 7.19 Mn | -36.83% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -36.83% |
| Mar 31, 2026 | -38.52% |
| Dec 31, 2025 | -43.41% |
| Sep 30, 2025 | -90.94% |
| Jun 30, 2025 | -118.72% |
| Mar 31, 2025 | -8.53% |
| Dec 31, 2024 | -31.32% |
| Sep 30, 2024 | -17.01% |
| Jun 30, 2024 | -16.42% |
| Mar 31, 2024 | -143.02% |
| Dec 31, 2023 | -94.49% |
| Sep 30, 2023 | -97.18% |
| Jun 30, 2023 | -109.49% |
| Mar 31, 2023 | -99.73% |
| Dec 31, 2022 | -86.33% |
| Sep 30, 2022 | -114.98% |
| Jun 30, 2022 | -123.21% |
| Mar 31, 2022 | -97.57% |
| Dec 31, 2021 | -84.78% |
| Sep 30, 2021 | -66.02% |
X4 Pharmaceuticals Return on Invested Capital [ROIC] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-invested-capital-%5Broic%5D&ticker=XFOR&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-invested-capital-[roic]", "ticker": "XFOR", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=return-on-invested-capital-%5Broic%5D&ticker=XFOR&period=max&api_key=YOUR_API_KEY");
const data = await res.json();