Wave Life Sciences (WVE) EBITDA Margin (2015 - 2026)
Wave Life Sciences (WVE) posted EBITDA Margin of -3210.56% for Q2 2026, down 2614.01 percentage points from -596.55% a year earlier and down 3130.93 percentage points from the prior quarter.
Wave Life Sciences (WVE) EBITDA Margin (2015 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, EBITDA Margin at Wave Life Sciences was -328.16%, down 200.15 percentage points year-over-year; for FY2025, it came in at -496.04%, down 397.70 percentage points from FY2024.
- Annual EBITDA Margin shows a five-year change of +227.49 percentage points (FY2020 to FY2025).
- In prior years, Wave Life Sciences' EBITDA Margin was -98.34% in FY2024 (-42.74 pp), -55.60% in FY2023 (+4222.83 pp), -4278.43% in FY2022 (-3986.67 pp) and -291.76% in FY2021 (+431.77 pp).
- The Q2 2026 figure stands as the lowest quarterly EBITDA Margin since Q4 2022.
- On a year-over-year basis, EBITDA Margin increased in three of the last eight quarters, with an average year-over-year change of -481.74 percentage points.
- The strongest year-over-year quarter for EBITDA Margin in the past five years was Q3 2023, with a gain of 13085.85 percentage points; the weakest was Q3 2022, with a drop of 13058.57 percentage points.
- According to Business Quant data, EBITDA Margin for the three prior quarters was -79.63% (Q1 2026), -322.55% (Q4 2025) and -729.46% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | Wave Life Sciences | 709.33 Mn | -1.00 Bn | - | -3,210.56% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -3,210.56% |
| Mar 31, 2026 | -79.63% |
| Dec 31, 2025 | -322.55% |
| Sep 30, 2025 | -729.46% |
| Jun 30, 2025 | -596.55% |
| Mar 31, 2025 | -533.29% |
| Dec 31, 2024 | 28.51% |
| Sep 30, 2024 | -820.31% |
| Jun 30, 2024 | -172.65% |
| Mar 31, 2024 | -266.52% |
| Dec 31, 2023 | -60.58% |
| Sep 30, 2023 | 11.46% |
| Jun 30, 2023 | -100.35% |
| Mar 31, 2023 | -223.16% |
| Dec 31, 2022 | -3,391.85% |
| Sep 30, 2022 | -13,074.39% |
| Jun 30, 2022 | -10,791.73% |
| Mar 31, 2022 | -2,077.94% |
| Dec 31, 2021 | -1,944.14% |
| Sep 30, 2021 | -15.81% |
Wave Life Sciences EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=WVE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "WVE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=WVE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();