Growth Metrics

Trevi Therapeutics (TRVI) Operating Income (2018 - 2025)

Trevi Therapeutics' quarterly Operating Income came in at -$10.2 million in Q4 2025, up 16.52% year-on-year from -$8.8 million in Q4 2024, and up 26.56% quarter-over-quarter from -$13.9 million in Q3 2025.

Trevi Therapeutics has reported Operating Income for 8 years, with the latest figure at -$10.2 million in Q4 2025.

  • For the quarter ending Q4 2025, Operating Income rose 16.52% year-over-year to -$10.2 million; the trailing twelve-month figure through Dec 2025 stood at -$50.1 million (up 2.76% YoY), and the FY2025 full-year result was -$49.3 million, up 4.26% from the prior year.
  • Operating Income for Q4 2025 stood at -$10.2 million, up from -$13.9 million in the prior quarter.
  • The five-year high for Operating Income was -$6.7 million in Q4 2022, with the low at -$14.1 million in Q3 2024.
  • Average Operating Income over 5 years is -$9.8 million, with a median of -$8.9 million recorded in 2023.
  • Year-over-year, Operating Income rose 19.53% in 2022 and plunged 58.54% in 2024.
  • Tracing TRVI's Operating Income over 5 years: stood at -$8.3 million in 2021, then gained by 19.53% to -$6.7 million in 2022, then plunged by 34.19% to -$8.9 million in 2023, then plunged by 37.05% to -$12.2 million in 2024, then advanced by 16.52% to -$10.2 million in 2025.
  • The last three Operating Income figures came in at -$10.2 million (Q4 2025), -$13.9 million (Q3 2025), and -$13.7 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 268.64 Mn
10 Trevi Therapeutics 2.02 Bn 1.85 Bn - -

Historic Data

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DateValue
Dec 31, 2025 -10.22 Mn
Sep 30, 2025 -13.92 Mn
Jun 30, 2025 -13.72 Mn
Dec 31, 2024 -12.24 Mn
Sep 30, 2024 -14.09 Mn
Jun 30, 2024 -13.29 Mn
Mar 31, 2024 -11.91 Mn
Dec 31, 2023 -8.93 Mn
Sep 30, 2023 -9.05 Mn
Jun 30, 2023 -8.38 Mn
Mar 31, 2023 -7.56 Mn
Dec 31, 2022 -6.66 Mn
Sep 30, 2022 -8.41 Mn
Jun 30, 2022 -7.82 Mn
Mar 31, 2022 -7.03 Mn
Dec 31, 2021 -8.27 Mn
Sep 30, 2021 -6.95 Mn
Jun 30, 2021 -9.17 Mn
Mar 31, 2021 -8.09 Mn
Dec 31, 2020 -9.19 Mn
Sep 30, 2020 -7.24 Mn
Jun 30, 2020 -7.41 Mn
Mar 31, 2020 -8.64 Mn
Dec 31, 2019 -6.77 Mn
Sep 30, 2019 -7.65 Mn
Jun 30, 2019 -7.42 Mn
Mar 31, 2019 -4.81 Mn
Dec 31, 2018 -5.93 Mn
Sep 30, 2018 -4.96 Mn
Jun 30, 2018 -4.38 Mn
Mar 31, 2018 -3.14 Mn