Synlogic (SYBX) Return on Equity [ROE] (2016 - 2026)
Synlogic's Return on Equity [ROE] came in at -18.54% for Q2 2026, down 2.42 percentage points from -16.12% a year earlier.
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Analysis
Synlogic (SYBX) Return on Equity [ROE] (2016 - 2026) Analysis & Trends
For FY2025, Synlogic's Return on Equity [ROE] was -8.17%, up 94.46 percentage points from FY2024.
- Return on Equity [ROE] carries a five-year change of +35.33 percentage points (FY2020 to FY2025).
- Going back by year, Return on Equity [ROE] was -102.63% in FY2024 (+3.58 pp), -106.21% in FY2023 (-48.66 pp), -57.55% in FY2022 (-11.39 pp) and -46.16% in FY2021 (-2.66 pp).
- The five-year range for quarterly Return on Equity [ROE] is -584.44% (Q2 2024) to 11.89% (Q1 2025).
- Year-over-year, Return on Equity [ROE] increased in four of the last seven quarters, with an average year-over-year change of +171.77 percentage points.
- The fastest year-over-year change in Return on Equity [ROE] over five years came in Q2 2025 (a gain of 568.32 percentage points), and the weakest in Q2 2024 (a drop of 478.73 percentage points).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,199.50 Bn | 1,168.08 Bn | 19.71 Bn | 82.09% |
| 2 | Johnson & Johnson | 635.17 Bn | 555.03 Bn | 17.30 Bn | 19.33% |
| 3 | AbbVie | 504.69 Bn | 477.85 Bn | 12.70 Bn | - |
| 4 | Merck | 358.43 Bn | 312.86 Bn | 12.21 Bn | 7.21% |
| 5 | Novartis Ag | 288.36 Bn | 252.75 Bn | 11.24 Bn | 31.52% |
| 6 | Astrazeneca | 265.78 Bn | 239.54 Bn | 12.86 Bn | 21.39% |
| 7 | Amgen | 237.46 Bn | 192.86 Bn | 7.24 Bn | 83.75% |
| 8 | Gilead Sciences | 193.65 Bn | 167.76 Bn | 6.22 Bn | -18.38% |
| 9 | Pfizer | 171.05 Bn | 118.00 Bn | 10.94 Bn | 4.97% |
| 10 | Synlogic | 11.23 Mn | -49.24 Mn | - | -18.54% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -18.54% |
| Dec 31, 2025 | -18.32% |
| Sep 30, 2025 | -37.12% |
| Jun 30, 2025 | -16.12% |
| Mar 31, 2025 | 11.89% |
| Dec 31, 2024 | -278.78% |
| Sep 30, 2024 | -410.61% |
| Jun 30, 2024 | -584.44% |
| Mar 31, 2024 | -398.12% |
| Dec 31, 2023 | -160.86% |
| Sep 30, 2023 | -121.08% |
| Jun 30, 2023 | -105.72% |
| Mar 31, 2023 | -87.32% |
| Dec 31, 2022 | -72.28% |
| Sep 30, 2022 | -59.27% |
| Jun 30, 2022 | -50.19% |
| Mar 31, 2022 | -43.84% |
| Dec 31, 2021 | -39.21% |
| Sep 30, 2021 | -41.47% |
| Jun 30, 2021 | -48.30% |
API Access
Synlogic Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SYBX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "SYBX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SYBX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();