SOPHiA GENETICS (SOPH) Return on Capital Employed (2021 - 2025)
SOPHiA GENETICS recorded quarterly Return on Capital Employed of 62.91% in Q4 2025, down 20.36% quarter-over-quarter from 52.27% in Q3 2025, and down 1524.0% year-over-year from 4.42% in Q4 2024.
SOPHiA GENETICS's Return on Capital Employed history runs 5 years deep, the most recent figure standing at 62.91% for Q4 2025.
- In Q4 2025, Return on Capital Employed fell 1524.0% year-over-year to 62.91%; the TTM figure through Dec 2025 stood at 62.91% (down 1524.0% YoY), while the FY2025 annual figure was 65.27%, down 2202.0% from the prior year.
- Return on Capital Employed came in at 62.91% for Q4 2025 at SOPHiA GENETICS, down from 52.27% in the prior quarter.
- In the past five years, Return on Capital Employed ranged from a high of 38.22% in Q3 2023 to a low of 10693602.09% in Q3 2021.
- A 5-year average of 1827938.96% and a median of 46.75% in 2024 frame the typical range for Return on Capital Employed.
- Across the five-year window, Return on Capital Employed jumped 1069356234 bps in 2022 and tumbled 1524 bps in 2025, its largest moves.
- SOPHiA GENETICS's Return on Capital Employed stood at 6858192.12% in 2021, then surged by 100 bps to 39.85% in 2022, then retreated by 10 bps to 43.92% in 2023, then fell by 9 bps to 47.67% in 2024, then slumped by 32 bps to 62.91% in 2025.
- According to Business Quant data, Return on Capital Employed over the past three periods registered 62.91%, 52.27%, and 52.74% for Q4 2025, Q3 2025, and Q2 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Veeva Systems | 30.85 Bn | 24.28 Bn | 622.47 Mn | 13.28% |
| 2 | BrightSpring Health Services | 12.29 Bn | 11.41 Bn | 482.22 Mn | 2.09% |
| 3 | Healthequity | 7.80 Bn | 7.48 Bn | 256.31 Mn | 10.67% |
| 4 | Hinge Health | 4.82 Bn | 4.51 Bn | 154.23 Mn | -163.65% |
| 5 | Doximity | 4.21 Bn | 3.46 Bn | 125.97 Mn | 21.81% |
| 6 | Waystar Holding | 4.18 Bn | 4.03 Bn | 268.04 Mn | 4.73% |
| 7 | 10x Genomics | 3.78 Bn | 3.24 Bn | 106.18 Mn | -4.23% |
| 8 | Privia Health | 2.65 Bn | 2.28 Bn | 595.71 Mn | 4.60% |
| 9 | Omnicell | 1.95 Bn | 1.78 Bn | 140.36 Mn | 2.23% |
| 10 | SOPHiA GENETICS | 24.12 Mn | -46.17 Mn | 14.69 Mn | -62.91% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -62.91% |
| Sep 30, 2025 | -52.27% |
| Jun 30, 2025 | -52.74% |
| Mar 31, 2025 | -52.30% |
| Dec 31, 2024 | -47.67% |
| Sep 30, 2024 | -45.84% |
| Jun 30, 2024 | -45.54% |
| Mar 31, 2024 | -45.57% |
| Dec 31, 2023 | -43.92% |
| Sep 30, 2023 | -38.22% |
| Jun 30, 2023 | -39.81% |
| Mar 31, 2023 | -39.35% |
| Dec 31, 2022 | -39.85% |
| Sep 30, 2022 | -39.75% |
| Jun 30, 2022 | -35.34% |
| Mar 31, 2022 | -5,712,782.33% |
| Dec 31, 2021 | -5,326,795.48% |
| Sep 30, 2021 | -8,305,778.32% |