SOPHiA GENETICS (SOPH) Return on Capital Employed (2021 - 2026)

SOPHiA GENETICS (SOPH) posted Return on Capital Employed of 62.91% for Q4 2025, down 20.36% sequentially from 52.27% in Q3 2025, and down 1524.0% YoY from 4.42% in Q4 2024.

SOPHiA GENETICS (SOPH) Return on Capital Employed (2021 - 2026) Analysis & Trends

SOPHiA GENETICS has reported Return on Capital Employed for 5 years, with the latest figure at 62.91% in Q4 2025.

  • Quarterly Return on Capital Employed fell 1524.0% year-over-year to 62.91% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 62.91% (down 1524.0% YoY) and the FY2025 annual result came in at 65.27%, down 2202.0% from the prior year.
  • Return on Capital Employed slipped to 62.91% in Q4 2025 per SOPH's latest filing, from 52.27% in the prior quarter.
  • Over five years, Return on Capital Employed peaked at 35.34% in Q2 2022 and troughed at 8305778.32% in Q3 2021.
  • A 5-year average of 1074779.84% and a median of 45.71% in 2024 frame the typical range for Return on Capital Employed.
  • The sharpest annual moves came in 2022 and 2025: Return on Capital Employed jumped 830573857 bps in 2022, then plunged 1524 bps in 2025.
  • Over 5 years, Return on Capital Employed stood at 5326795.48% in 2021, then jumped by 100 bps to 39.85% in 2022, then decreased by 10 bps to 43.92% in 2023, then retreated by 9 bps to 47.67% in 2024, then tumbled by 32 bps to 62.91% in 2025.
  • According to Business Quant data, Return on Capital Employed over the past three periods registered 62.91%, 52.27%, and 52.74% for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Veeva Systems 39.72 Bn 32.40 Bn 662.02 Mn 13.00%
2 BrightSpring Health Services 12.19 Bn 11.64 Bn 492.75 Mn 9.85%
3 Healthequity 8.79 Bn 8.52 Bn 256.31 Mn 10.67%
4 10x Genomics 7.31 Bn 6.76 Bn 112.50 Mn -9.77%
5 Hinge Health 7.10 Bn 6.71 Bn 183.95 Mn 31.58%
6 MiniMed 5.66 Bn 5.36 Bn 480.00 Mn -8.46%
7 Waystar Holding 4.76 Bn 4.56 Bn 221.99 Mn 4.91%
8 Doximity 4.46 Bn 3.77 Bn 132.93 Mn 20.35%
9 Heartflow 3.66 Bn 3.28 Bn 53.19 Mn -20.94%
10 SOPHiA GENETICS 553.79 Mn 446.12 Mn - -58.15%

Historic Data

Download Data
DateValue
Jun 30, 2026 -58.15%
Dec 31, 2025 -62.91%
Sep 30, 2025 -52.27%
Jun 30, 2025 -52.74%
Mar 31, 2025 -52.30%
Dec 31, 2024 -47.67%
Sep 30, 2024 -45.84%
Jun 30, 2024 -45.54%
Mar 31, 2024 -45.57%
Dec 31, 2023 -43.92%
Sep 30, 2023 -38.22%
Jun 30, 2023 -39.81%
Mar 31, 2023 -39.35%
Dec 31, 2022 -39.85%
Sep 30, 2022 -39.75%
Jun 30, 2022 -35.34%
Mar 31, 2022 -5,712,782.33%
Dec 31, 2021 -5,326,795.48%
Sep 30, 2021 -8,305,778.32%