SOPHiA GENETICS (SOPH) Return on Capital Employed (2021 - 2025)
SOPHiA GENETICS (SOPH) reported Return on Capital Employed of 62.91% for Q4 2025, down 1524.0% on a YoY basis from 4.42% in Q4 2024, and down 20.36% sequentially from 52.27% in Q3 2025.
SOPHiA GENETICS (SOPH) Return on Capital Employed (2021 - 2025) Analysis & Trends
SOPHiA GENETICS (SOPH) has 5 years of Return on Capital Employed data on file, last reported at 62.91% in Q4 2025.
- For the quarter ending Q4 2025, Return on Capital Employed fell 1524.0% year-over-year to 62.91%; the trailing twelve-month figure through Dec 2025 stood at 62.91% (down 1524.0% YoY), and the FY2025 full-year result was 65.27%, down 2202.0% from the prior year.
- Return on Capital Employed slipped to 62.91% in Q4 2025, from 52.27% in the prior quarter.
- In the past five years, Return on Capital Employed ranged from a high of 23.91% in Q4 2021 to a low of 62.91% in Q4 2025.
- A 5-year average of 42.6% and a median of 41.88% in 2022 frame the typical range for Return on Capital Employed.
- Across the five-year window, Return on Capital Employed slumped 1593 bps in 2022 and surged 153 bps in 2023, its largest moves.
- Tracing SOPH's Return on Capital Employed over 5 years: stood at 23.91% in 2021, then slumped by 67 bps to 39.85% in 2022, then declined by 10 bps to 43.92% in 2023, then dropped by 9 bps to 47.67% in 2024, then plunged by 32 bps to 62.91% in 2025.
- Business Quant data shows SOPH's Return on Capital Employed at 62.91% in Q4 2025, 52.27% in Q3 2025, and 52.74% in Q2 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Veeva Systems | 29.34 Bn | 22.03 Bn | 662.02 Mn | 13.00% |
| 2 | BrightSpring Health Services | 13.49 Bn | 12.59 Bn | 482.22 Mn | 7.68% |
| 3 | Healthequity | 7.96 Bn | 7.70 Bn | 256.31 Mn | 10.67% |
| 4 | 10x Genomics | 6.17 Bn | 5.63 Bn | 106.18 Mn | -4.23% |
| 5 | Hinge Health | 6.02 Bn | 5.70 Bn | 154.23 Mn | -163.65% |
| 6 | MiniMed | 4.19 Bn | 3.89 Bn | 480.00 Mn | -8.46% |
| 7 | Waystar Holding | 4.14 Bn | 4.07 Bn | 216.84 Mn | 4.73% |
| 8 | Doximity | 3.82 Bn | 3.08 Bn | 125.97 Mn | 21.81% |
| 9 | Privia Health | 3.10 Bn | 2.73 Bn | - | 4.60% |
| 10 | SOPHiA GENETICS | 408.62 Mn | 338.33 Mn | 14.69 Mn | -62.91% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -62.91% |
| Sep 30, 2025 | -52.27% |
| Jun 30, 2025 | -52.74% |
| Mar 31, 2025 | -52.30% |
| Dec 31, 2024 | -47.67% |
| Sep 30, 2024 | -45.84% |
| Jun 30, 2024 | -45.54% |
| Mar 31, 2024 | -45.57% |
| Dec 31, 2023 | -43.92% |
| Sep 30, 2023 | -38.22% |
| Jun 30, 2023 | -39.81% |
| Mar 31, 2023 | -39.35% |
| Dec 31, 2022 | -39.85% |
| Sep 30, 2022 | -39.75% |
| Jun 30, 2022 | -35.34% |
| Mar 31, 2022 | -29.58% |
| Dec 31, 2021 | -23.91% |
| Sep 30, 2021 | -32.22% |