Silence Therapeutics (SLN) Enterprise Value (2018 - 2026)

Silence Therapeutics (SLN) posted Enterprise Value of -$134.5 million for Q1 2026, down 58.05% sequentially from -$85.1 million in Q4 2025, and up 35.37% YoY from -$99.4 million in Q1 2025.

Silence Therapeutics (SLN) Enterprise Value (2018 - 2026) Analysis & Trends

Silence Therapeutics has reported Enterprise Value for 9 years, with the latest figure at -$134.5 million in Q1 2026.

  • Quarterly Enterprise Value rose 35.37% year-over-year to -$134.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$134.5 million (up 35.37% YoY) and the FY2025 annual result came in at -$85.1 million, up 54.26% from the prior year.
  • Enterprise Value declined to -$134.5 million in Q1 2026 per SLN's latest filing, from -$85.1 million in the prior quarter.
  • Over five years, Enterprise Value peaked at -$64.3 million in Q4 2022 and troughed at -$208.1 million in Q1 2025.
  • A 5-year average of -$122.7 million and a median of -$118.3 million in 2025 frame the typical range for Enterprise Value.
  • The sharpest annual moves came in 2024 and 2025: Enterprise Value slumped 177.47% in 2024, then surged 54.26% in 2025.
  • Over 5 years, Enterprise Value stood at -$64.3 million in 2022, then decreased by 4.3% to -$67.1 million in 2023, then plunged by 177.47% to -$186.1 million in 2024, then soared by 54.26% to -$85.1 million in 2025, then slumped by 58.05% to -$134.5 million in 2026.
  • According to Business Quant data, Enterprise Value over the past three periods registered -$134.5 million, -$85.1 million, and -$122.4 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn -7.85 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -7.99 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -5.18 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -3.94 Bn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn -5.10 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -8.46 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 2.12 Bn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -3.31 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.16 Bn
10 Silence Therapeutics 648.22 Mn 576.12 Mn - -72.10 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -72.10 Mn
Mar 31, 2026 -134.52 Mn
Dec 31, 2025 -85.11 Mn
Sep 30, 2025 -122.36 Mn
Jun 30, 2025 -114.16 Mn
Mar 31, 2025 -208.15 Mn
Dec 31, 2024 -186.07 Mn
Dec 31, 2023 -67.06 Mn
Dec 31, 2022 -64.30 Mn
Dec 31, 2021 -99.13 Mn
Dec 31, 2020 -38.22 Mn
Dec 31, 2019 -17.38 Mn
Dec 31, 2018 -27.66 Mn