Sionna Therapeutics (SION) Free Cash Flow (2024 - 2026)

Quarterly results put Free Cash Flow at -$21.8 million for Q1 2026, down 33.38% from a year ago — trailing twelve months through Mar 2026 was -$72.1 million (down 28.79% YoY), and the annual figure for FY2025 was -$66.7 million, down 26.24%.

Sionna Therapeutics has reported Free Cash Flow over the past 3 years, most recently at -$21.8 million for Q1 2026.

  • Free Cash Flow reached -$21.8 million in Q1 2026 per SION's latest filing, down from -$16.8 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$10.1 million in Q2 2024 and bottomed at -$21.8 million in Q1 2026.
  • Median Free Cash Flow over the past 3 years was -$16.4 million (2025), compared with a mean of -$15.7 million.
  • Peak annual rise in Free Cash Flow hit 13.39% in 2025, while the deepest fall reached 78.94% in 2025.
  • Over 3 years, Free Cash Flow stood at -$11.8 million in 2024, then plummeted by 42.53% to -$16.8 million in 2025, then fell by 29.77% to -$21.8 million in 2026.
  • Business Quant data shows Free Cash Flow for SION at -$21.8 million in Q1 2026, -$16.8 million in Q4 2025, and -$15.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - -1.67 Mn
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn -12.20 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -2.49 Mn
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 1.29 Bn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn 848.30 Mn
8 Evaxion A 65.12 Bn 65.10 Bn - -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 48.67 Mn
10 Sionna Therapeutics 1.87 Bn 1.87 Bn - -21.84 Mn

Historic Data

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DateValue
Mar 31, 2026 -21.84 Mn
Mar 31, 2026 -21.84 Mn
Dec 31, 2025 -16.83 Mn
Dec 31, 2025 -16.83 Mn
Sep 30, 2025 -15.32 Mn
Sep 30, 2025 -15.32 Mn
Jun 30, 2025 -18.15 Mn
Jun 30, 2025 -18.15 Mn
Mar 31, 2025 -16.37 Mn
Mar 31, 2025 -16.37 Mn
Dec 31, 2024 -11.81 Mn
Dec 31, 2024 -11.81 Mn
Sep 30, 2024 -17.69 Mn
Sep 30, 2024 -17.69 Mn
Jun 30, 2024 -10.15 Mn
Jun 30, 2024 -10.15 Mn
Mar 31, 2024 -13.18 Mn
Mar 31, 2024 -13.18 Mn