Sionna Therapeutics (SION) Free Cash Flow (2024 - 2026)

Sionna Therapeutics (SION) posted Free Cash Flow of -$21.8 million for Q1 2026, down 29.77% sequentially from -$16.8 million in Q4 2025, and down 33.38% YoY from -$32.8 million in Q1 2025.

Sionna Therapeutics (SION) Free Cash Flow (2024 - 2026) Analysis & Trends

Sionna Therapeutics has reported Free Cash Flow for 3 years, with the latest figure at -$21.8 million in Q1 2026.

  • Quarterly Free Cash Flow fell 33.38% year-over-year to -$21.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$72.1 million (down 28.79% YoY) and the FY2025 annual result came in at -$66.7 million, down 26.24% from the prior year.
  • Free Cash Flow declined to -$21.8 million in Q1 2026 per SION's latest filing, from -$16.8 million in the prior quarter.
  • Over five years, Free Cash Flow peaked at -$10.1 million in Q2 2024 and troughed at -$21.8 million in Q1 2026.
  • A 3-year average of -$15.7 million and a median of -$16.4 million in 2025 frame the typical range for Free Cash Flow.
  • The widest YoY moves for Free Cash Flow: up 13.39% in 2025, down 78.94% in 2025.
  • Over 3 years, Free Cash Flow stood at -$11.8 million in 2024, then sank by 42.53% to -$16.8 million in 2025, then declined by 29.77% to -$21.8 million in 2026.
  • According to Business Quant data, Free Cash Flow over the past three periods registered -$21.8 million, -$16.8 million, and -$15.3 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.01 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 572.80 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -389.61 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 437.80 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -2.33 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 477.44 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 292.04 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -95.09 Mn
10 Sionna Therapeutics 291.76 Mn 291.76 Mn - -22.22 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -22.22 Mn
Jun 30, 2026 -22.22 Mn
Mar 31, 2026 -21.84 Mn
Mar 31, 2026 -21.84 Mn
Dec 31, 2025 -16.83 Mn
Dec 31, 2025 -16.83 Mn
Sep 30, 2025 -15.32 Mn
Sep 30, 2025 -15.32 Mn
Jun 30, 2025 -18.15 Mn
Jun 30, 2025 -18.15 Mn
Mar 31, 2025 -16.37 Mn
Mar 31, 2025 -16.37 Mn
Dec 31, 2024 -11.81 Mn
Dec 31, 2024 -11.81 Mn
Sep 30, 2024 -17.69 Mn
Sep 30, 2024 -17.69 Mn
Jun 30, 2024 -10.15 Mn
Jun 30, 2024 -10.15 Mn
Mar 31, 2024 -13.18 Mn
Mar 31, 2024 -13.18 Mn