Avidity Biosciences, Inc. (RNA) Return on Sales (2019 - 2025)

Avidity Biosciences' Return on Sales history spans 7 years, with the latest figure at 275.14% for Q4 2025.

  • For Q4 2025, Return on Sales fell 24068.0% year-over-year to 275.14%; the TTM value through Dec 2025 reached 36.4%, down 685.0%, while the annual FY2025 figure was 36.4%, 685.0% down from the prior year.
  • Return on Sales reached 275.14% in Q4 2025 per RNA's latest filing, down from 13.95% in the prior quarter.
  • In the past five years, Return on Sales ranged from a high of 8.82% in Q1 2021 to a low of 275.14% in Q4 2025.
  • Average Return on Sales over 5 years is 37.23%, with a median of 20.51% recorded in 2023.
  • The largest YoY upside for Return on Sales was 2036bps in 2025 against a maximum downside of -24068bps in 2025.
  • A 5-year view of Return on Sales shows it stood at 20.78% in 2021, then grew by 12bps to 18.22% in 2022, then crashed by -51bps to 27.51% in 2023, then dropped by -25bps to 34.46% in 2024, then tumbled by -698bps to 275.14% in 2025.
  • Per Business Quant, the three most recent readings for RNA's Return on Sales are 275.14% (Q4 2025), 13.95% (Q3 2025), and 40.72% (Q2 2025).