Avidity Biosciences, Inc. (RNA) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

137,355,906Shares Outstanding

9,475,343Shares held by institutions

$690,373,491Value of institutional holdings

103.02%Institutional ownership %

15.26%Shares Changed QoQ

327No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Avidity Biosciences, Inc. (NASDAQ:RNA) includes 327 filers as of the latest reporting cycle ending December 2025.

Institutional ownership in Avidity Biosciences edged down to 103.0% in December 2025, compared to 117.8% in September 2025.
Institutional share ownership changed by 15.26% QoQ, while the number of institutional owners saw an increase of 39.74% YoY.
The latest 13F cycle for Avidity Biosciences reveals that of 327 total investors, 217 funds grew their exposure, whereas 81 reduced theirs and 29 made no changes.
The aggregate institutional position in Avidity Biosciences now stands at 141.51Mn shares as of December 2025, after investors increased their holdings (up by 18.74Mn shares quarter on quarter which is up 14.01Mn shares year over year).
VANGUARD GROUP INC continues to be the largest institutional holder of Avidity Biosciences as of December 31, 2025, with a position of 13.65Mn shares, representing 9.94% of the company's outstanding stock.
Among the most significant buyers of Avidity Biosciences during December 2025 were BALYASNY ASSET MANAGEMENT L.P. (6.04Mn), Pentwater Capital Management LP (6.03Mn), HBK INVESTMENTS L P (4.37Mn), BlackRock, Inc. (3.65Mn), NORGES BANK (3.05Mn).
Leading sellers of Avidity Biosciences stock in December 2025 included FMR LLC (21.40Mn), WELLINGTON MANAGEMENT GROUP LLP (9.34Mn), JANUS HENDERSON GROUP PLC (7.58Mn), Avoro Capital Advisors LLC (2.19Mn), Pictet Asset Management Holding SA (1.25Mn).
The top 10 institutional holders of Avidity Biosciences for the quarter ending December 2025 included VANGUARD GROUP INC (13.65Mn), BlackRock, Inc. (12.85Mn), RA CAPITAL MANAGEMENT, L.P. (8.64Mn), JANUS HENDERSON GROUP PLC (6.94Mn), BALYASNY ASSET MANAGEMENT L.P. (6.04Mn), Pentwater Capital Management LP (6.03Mn), Avoro Capital Advisors LLC (5.46Mn), HBK INVESTMENTS L P (4.37Mn), STATE STREET CORP (4.10Mn), GOLDMAN SACHS GROUP INC (3.78Mn).

327 Institutional Holders

9,475,343 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
VANGUARD GROUP INC	31 Dec, 2025	13,649,250	429,491	3.25%	$984,520,403.00
BlackRock, Inc.	31 Dec, 2025	12,850,801	3,648,222	39.64%	$926,928,275.00
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	8,641,031	0	0.00%	$623,277,566.00
JANUS HENDERSON GROUP PLC	31 Dec, 2025	6,939,503	-7,583,412	-52.22%	$500,560,229.00
BALYASNY ASSET MANAGEMENT L.P.	31 Dec, 2025	6,040,590	6,040,590	0.00%	$435,707,757.00
Pentwater Capital Management LP	31 Dec, 2025	6,026,500	6,026,500	0.00%	$434,691,445.00
Avoro Capital Advisors LLC	31 Dec, 2025	5,455,000	-2,190,000	-28.65%	$393,469,150.00
HBK INVESTMENTS L P	31 Dec, 2025	4,365,000	4,365,000	0.00%	$314,847,450.00
STATE STREET CORP	31 Dec, 2025	4,097,885	-790,747	-16.18%	$295,580,445.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	3,776,785	2,044,316	118.00%	$272,419,502.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	3,120,780	262,731	9.19%	$225,144,631.00
NORGES BANK	31 Dec, 2025	3,046,388	3,046,388	0.00%	$219,735,966.00
Bellevue Group AG	31 Dec, 2025	2,630,969	478,107	22.21%	$189,771,794.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	2,630,966	1,430,966	119.25%	$189,771,578.00
GLAZER CAPITAL, LLC	31 Dec, 2025	2,467,139	2,467,139	0.00%	$177,955.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	2,415,270	2,377,747	6,336.77%	$174,213,425.00
UBS Group AG	31 Dec, 2025	2,376,112	1,060,253	80.57%	$171,388,958.00
TIG Advisors, LLC	31 Dec, 2025	1,801,683	1,801,683	0.00%	$129,955,395.00
CITADEL ADVISORS LLC	31 Dec, 2025	1,592,429	692,665	76.98%	$114,861,904.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	1,181,661	57,884	5.15%	$85,233,208.00

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