Relay Therapeutics (RLAY) Free Cash Flow (2019 - 2026)

Relay Therapeutics (RLAY) reported Free Cash Flow of -$51.1 million for Q1 2026, up 30.55% year-over-year from -$39.2 million in Q1 2025, and down 13.92% on a QoQ basis from -$44.9 million in Q4 2025.

Relay Therapeutics (RLAY) has 8 years of Free Cash Flow data on file, last reported at -$51.1 million in Q1 2026.

  • Quarterly Free Cash Flow rose 30.55% year-over-year to -$51.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$213.4 million (up 21.73% YoY) and the FY2025 annual result came in at -$235.9 million, up 6.08% from the prior year.
  • Free Cash Flow retreated to -$51.1 million in Q1 2026 per RLAY's latest filing, from -$44.9 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$44.9 million in Q4 2025 and bottomed at -$89.3 million in Q4 2023.
  • The 5-year median for Free Cash Flow is -$62.1 million (2025), against an average of -$63.6 million.
  • The widest annual swing landed in 2022, when Free Cash Flow sank 211.66%; it then jumped 35.2% in 2024.
  • Tracing RLAY's Free Cash Flow over 5 years: stood at -$59.4 million in 2022, then plunged by 50.36% to -$89.3 million in 2023, then jumped by 35.2% to -$57.9 million in 2024, then increased by 22.47% to -$44.9 million in 2025, then dropped by 13.92% to -$51.1 million in 2026.
  • Per Business Quant, the three latest RLAY Free Cash Flow figures stand at -$51.1 million (Q1 2026), -$44.9 million (Q4 2025), and -$62.1 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -1.67 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -12.20 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -2.49 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.29 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 848.30 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 48.67 Mn
10 Relay Therapeutics 2.53 Bn 2.53 Bn - -51.11 Mn

Historic Data

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DateValue
Mar 31, 2026 -51.11 Mn
Mar 31, 2026 -51.11 Mn
Dec 31, 2025 -44.87 Mn
Dec 31, 2025 -44.87 Mn
Sep 30, 2025 -62.12 Mn
Sep 30, 2025 -62.12 Mn
Jun 30, 2025 -55.29 Mn
Jun 30, 2025 -55.29 Mn
Mar 31, 2025 -73.59 Mn
Mar 31, 2025 -73.59 Mn
Dec 31, 2024 -57.87 Mn
Dec 31, 2024 -57.87 Mn
Sep 30, 2024 -75.31 Mn
Sep 30, 2024 -75.31 Mn
Jun 30, 2024 -65.84 Mn
Jun 30, 2024 -65.84 Mn
Mar 31, 2024 -52.10 Mn
Mar 31, 2024 -52.10 Mn
Dec 31, 2023 -89.31 Mn
Dec 31, 2023 -89.31 Mn
Sep 30, 2023 -75.99 Mn
Sep 30, 2023 -75.99 Mn
Jun 30, 2023 -70.10 Mn
Jun 30, 2023 -70.10 Mn
Mar 31, 2023 -69.05 Mn
Mar 31, 2023 -69.05 Mn
Dec 31, 2022 -59.40 Mn
Dec 31, 2022 -59.40 Mn
Sep 30, 2022 -68.24 Mn
Sep 30, 2022 -68.24 Mn
Jun 30, 2022 -58.95 Mn
Jun 30, 2022 -58.95 Mn
Mar 31, 2022 -51.97 Mn
Mar 31, 2022 -51.97 Mn
Dec 31, 2021 -40.59 Mn
Dec 31, 2021 -40.59 Mn
Sep 30, 2021 -54.71 Mn
Sep 30, 2021 -54.71 Mn
Jun 30, 2021 -29.12 Mn
Jun 30, 2021 -29.12 Mn
Mar 31, 2021 46.54 Mn
Mar 31, 2021 46.54 Mn
Dec 31, 2020 -35.34 Mn
Dec 31, 2020 -35.34 Mn
Sep 30, 2020 -25.58 Mn
Sep 30, 2020 -25.58 Mn
Jun 30, 2020 -21.12 Mn
Jun 30, 2020 -21.12 Mn
Mar 31, 2020 -22.39 Mn
Mar 31, 2020 -22.39 Mn
Dec 31, 2019 -30.74 Mn
Dec 31, 2019 -30.74 Mn
Sep 30, 2019 -16.37 Mn
Sep 30, 2019 -16.37 Mn