Protagonist Therapeutics (PTGX) Free Cash Flow (2015 - 2026)
Protagonist Therapeutics (PTGX) posted Free Cash Flow of -$49.1 million for Q1 2026, down 27.22% sequentially from -$38.6 million in Q4 2025, and down 139.3% YoY from $124.8 million in Q1 2025.
Analysis
Protagonist Therapeutics (PTGX) Free Cash Flow (2015 - 2026) Analysis & Trends
Protagonist Therapeutics has reported Free Cash Flow for 12 years, with the latest figure at -$49.1 million in Q1 2026.
- Quarterly Free Cash Flow fell 139.3% year-over-year to -$49.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$117.8 million (down 135.13% YoY) and the FY2025 annual result came in at $56.1 million, down 69.32% from the prior year.
- Free Cash Flow declined to -$49.1 million in Q1 2026 per PTGX's latest filing, from -$38.6 million in the prior quarter.
- Over five years, Free Cash Flow peaked at $268.6 million in Q2 2024 and troughed at -$49.1 million in Q1 2026.
- A 5-year average of $636705.9 and a median of -$27.7 million in 2024 frame the typical range for Free Cash Flow.
- The widest YoY moves for Free Cash Flow: up 1116.84% in 2024, down 274.06% in 2024.
- Over 5 years, Free Cash Flow stood at -$31.6 million in 2022, then soared by 153.62% to $16.9 million in 2023, then plunged by 274.06% to -$29.5 million in 2024, then sank by 30.75% to -$38.6 million in 2025, then decreased by 27.22% to -$49.1 million in 2026.
- According to Business Quant data, Free Cash Flow over the past three periods registered -$49.1 million, -$38.6 million, and -$1.8 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Free Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 1.01 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 572.80 Mn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | - |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -563.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | -389.61 Mn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 437.80 Mn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 292.04 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 477.44 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -95.09 Mn |
| 10 | Protagonist Therapeutics | 9.61 Bn | 9.61 Bn | - | 218.44 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 218.44 Mn |
| Mar 31, 2026 | -49.16 Mn |
| Dec 31, 2025 | -37.12 Mn |
| Sep 30, 2025 | -2.03 Mn |
| Jun 30, 2025 | -29.59 Mn |
| Mar 31, 2025 | 124.82 Mn |
| Dec 31, 2024 | -29.49 Mn |
| Sep 30, 2024 | -28.63 Mn |
| Jun 30, 2024 | 268.59 Mn |
| Mar 31, 2024 | -27.67 Mn |
| Dec 31, 2023 | 16.94 Mn |
| Sep 30, 2023 | -27.02 Mn |
| Jun 30, 2023 | -26.41 Mn |
| Mar 31, 2023 | -34.36 Mn |
| Dec 31, 2022 | -31.71 Mn |
| Sep 30, 2022 | -25.36 Mn |
| Jun 30, 2022 | -13.93 Mn |
| Mar 31, 2022 | -37.94 Mn |
| Dec 31, 2021 | -27.14 Mn |
| Sep 30, 2021 | -28.74 Mn |