Protagonist Therapeutics (PTGX) Free Cash Flow (2015 - 2026)

Protagonist Therapeutics' (PTGX) quarterly Free Cash Flow came in at -$49.2 million in Q1 2026, down 139.22% year-on-year from $125.3 million in Q1 2025, and down 27.49% quarter-over-quarter from -$38.6 million in Q4 2025.

Protagonist Therapeutics (PTGX) Free Cash Flow (2015 - 2026) Analysis & Trends

Protagonist Therapeutics has disclosed Free Cash Flow across 12 years of filings, most recently posting -$49.2 million for Q1 2026.

  • Free Cash Flow for Q1 2026 came in at -$49.2 million, down 139.22% year-over-year; the trailing twelve-month figure through Mar 2026 was -$118.4 million (down 135.28% YoY), and the FY2025 annual result was $56.1 million, down 69.32% from the prior year.
  • Free Cash Flow came in at -$49.2 million for Q1 2026 at Protagonist Therapeutics, down from -$38.6 million in the prior quarter.
  • In the past five years, Free Cash Flow ranged from a high of $268.4 million in Q2 2024 to a low of -$49.2 million in Q1 2026.
  • The 5-year median for Free Cash Flow is -$27.5 million (2024), against an average of $584882.4.
  • Peak annual rise in Free Cash Flow reached 1116.1% in 2024, while the deepest fall reached 278.31% in 2024.
  • Protagonist Therapeutics' Free Cash Flow stood at -$31.7 million in 2022, then jumped by 153.43% to $16.9 million in 2023, then tumbled by 278.31% to -$30.2 million in 2024, then declined by 27.64% to -$38.6 million in 2025, then dropped by 27.49% to -$49.2 million in 2026.
  • The last three Free Cash Flow figures came in at -$49.2 million (Q1 2026), -$38.6 million (Q4 2025), and -$587000.0 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -1.67 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -12.20 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.49 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.29 Bn
9 Abivax 91.96 Bn 91.96 Bn - 63,220.27
10 Protagonist Therapeutics 7.35 Bn 7.35 Bn - -49.16 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -49.16 Mn
Mar 31, 2026 -49.16 Mn
Dec 31, 2025 -38.56 Mn
Dec 31, 2025 -38.56 Mn
Sep 30, 2025 -587,000.00
Sep 30, 2025 -587,000.00
Jun 30, 2025 -30.11 Mn
Jun 30, 2025 -30.11 Mn
Mar 31, 2025 125.33 Mn
Mar 31, 2025 125.33 Mn
Dec 31, 2024 -30.21 Mn
Dec 31, 2024 -30.21 Mn
Sep 30, 2024 -27.91 Mn
Sep 30, 2024 -27.91 Mn
Jun 30, 2024 268.39 Mn
Jun 30, 2024 268.39 Mn
Mar 31, 2024 -27.47 Mn
Mar 31, 2024 -27.47 Mn
Dec 31, 2023 16.94 Mn
Dec 31, 2023 16.94 Mn