Protagonist Therapeutics (PTGX) Free Cash Flow (2015 - 2026)

Protagonist Therapeutics (PTGX) reported Free Cash Flow of -$49.1 million for Q1 2026, down 139.3% on a YoY basis from $124.8 million in Q1 2025, and down 27.22% sequentially from -$38.6 million in Q4 2025.

Protagonist Therapeutics (PTGX) Free Cash Flow (2015 - 2026) Analysis & Trends

Protagonist Therapeutics (PTGX) has 12 years of Free Cash Flow data on file, last reported at -$49.1 million in Q1 2026.

  • For the quarter ending Q1 2026, Free Cash Flow fell 139.3% year-over-year to -$49.1 million; the trailing twelve-month figure through Mar 2026 stood at -$117.8 million (down 135.13% YoY), and the FY2025 full-year result was $56.1 million, down 69.32% from the prior year.
  • Free Cash Flow declined to -$49.1 million in Q1 2026, from -$38.6 million in the prior quarter.
  • In the past five years, Free Cash Flow ranged from a high of $268.6 million in Q2 2024 to a low of -$49.1 million in Q1 2026.
  • A 5-year average of $636705.9 and a median of -$27.7 million in 2024 frame the typical range for Free Cash Flow.
  • Peak annual rise in Free Cash Flow reached 1116.84% in 2024, while the deepest fall reached 274.06% in 2024.
  • Tracing PTGX's Free Cash Flow over 5 years: stood at -$31.6 million in 2022, then soared by 153.62% to $16.9 million in 2023, then sank by 274.06% to -$29.5 million in 2024, then slumped by 30.75% to -$38.6 million in 2025, then declined by 27.22% to -$49.1 million in 2026.
  • Business Quant data shows PTGX's Free Cash Flow at -$49.1 million in Q1 2026, -$38.6 million in Q4 2025, and -$1.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -19.58 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 158.09 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.53 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -354.95 Mn
10 Protagonist Therapeutics 8.81 Bn 8.81 Bn - -49.05 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -49.05 Mn
Mar 31, 2026 -49.05 Mn
Dec 31, 2025 -38.56 Mn
Dec 31, 2025 -38.56 Mn
Sep 30, 2025 -1.84 Mn
Sep 30, 2025 -1.84 Mn
Jun 30, 2025 -28.34 Mn
Jun 30, 2025 -28.34 Mn
Mar 31, 2025 124.82 Mn
Mar 31, 2025 124.82 Mn
Dec 31, 2024 -29.49 Mn
Dec 31, 2024 -29.49 Mn
Sep 30, 2024 -28.63 Mn
Sep 30, 2024 -28.63 Mn
Jun 30, 2024 268.59 Mn
Jun 30, 2024 268.59 Mn
Mar 31, 2024 -27.67 Mn
Mar 31, 2024 -27.67 Mn
Dec 31, 2023 16.94 Mn
Dec 31, 2023 16.94 Mn