Protagonist Therapeutics PTGX
NASDAQ PTGX
$145.65 -3.15 (-2.12%)
As of: Sep 4, 2026 · 3:59 PM EDT

Protagonist Therapeutics (PTGX) Free Cash Flow (2015 - 2026)

Protagonist Therapeutics (PTGX) posted Free Cash Flow of -$49.1 million for Q1 2026, down 27.22% sequentially from -$38.6 million in Q4 2025, and down 139.3% YoY from $124.8 million in Q1 2025.

Analysis

Protagonist Therapeutics (PTGX) Free Cash Flow (2015 - 2026) Analysis & Trends

Protagonist Therapeutics has reported Free Cash Flow for 12 years, with the latest figure at -$49.1 million in Q1 2026.

  • Quarterly Free Cash Flow fell 139.3% year-over-year to -$49.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$117.8 million (down 135.13% YoY) and the FY2025 annual result came in at $56.1 million, down 69.32% from the prior year.
  • Free Cash Flow declined to -$49.1 million in Q1 2026 per PTGX's latest filing, from -$38.6 million in the prior quarter.
  • Over five years, Free Cash Flow peaked at $268.6 million in Q2 2024 and troughed at -$49.1 million in Q1 2026.
  • A 5-year average of $636705.9 and a median of -$27.7 million in 2024 frame the typical range for Free Cash Flow.
  • The widest YoY moves for Free Cash Flow: up 1116.84% in 2024, down 274.06% in 2024.
  • Over 5 years, Free Cash Flow stood at -$31.6 million in 2022, then soared by 153.62% to $16.9 million in 2023, then plunged by 274.06% to -$29.5 million in 2024, then sank by 30.75% to -$38.6 million in 2025, then decreased by 27.22% to -$49.1 million in 2026.
  • According to Business Quant data, Free Cash Flow over the past three periods registered -$49.1 million, -$38.6 million, and -$1.8 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 1.01 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 572.80 Mn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -563.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - -389.61 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 437.80 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 292.04 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 477.44 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -95.09 Mn
10 Protagonist Therapeutics 9.61 Bn 9.61 Bn - 218.44 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 218.44 Mn
Mar 31, 2026 -49.16 Mn
Dec 31, 2025 -37.12 Mn
Sep 30, 2025 -2.03 Mn
Jun 30, 2025 -29.59 Mn
Mar 31, 2025 124.82 Mn
Dec 31, 2024 -29.49 Mn
Sep 30, 2024 -28.63 Mn
Jun 30, 2024 268.59 Mn
Mar 31, 2024 -27.67 Mn
Dec 31, 2023 16.94 Mn
Sep 30, 2023 -27.02 Mn
Jun 30, 2023 -26.41 Mn
Mar 31, 2023 -34.36 Mn
Dec 31, 2022 -31.71 Mn
Sep 30, 2022 -25.36 Mn
Jun 30, 2022 -13.93 Mn
Mar 31, 2022 -37.94 Mn
Dec 31, 2021 -27.14 Mn
Sep 30, 2021 -28.74 Mn