Personalis (PSNL) Return on Equity [ROE] (2019 - 2026)
Personalis (PSNL) recorded Return on Equity [ROE] of -43.75% in Q2 2026, up 2.12 percentage points from -45.87% a year earlier but down 6.71 percentage points from the prior quarter.
Powered by 
Analysis
Personalis (PSNL) Return on Equity [ROE] (2019 - 2026) Analysis & Trends
For FY2025, Personalis reported Return on Equity [ROE] of -35.02%, up 13.89 percentage points from FY2024.
- Annual Return on Equity [ROE] has a five-year change of -7.65 percentage points (FY2020 to FY2025).
- Across earlier years, Return on Equity [ROE] came in at -48.91% in FY2024 (+13.41 pp), -62.31% in FY2023 (-19.43 pp), -42.89% in FY2022 (-17.07 pp) and -25.82% in FY2021 (+1.55 pp).
- Quarterly Return on Equity [ROE] has ranged from -77.18% in Q4 2023 to -17.58% in Q3 2021 over the past five years.
- On a year-over-year basis, Return on Equity [ROE] has increased for eight consecutive quarters, with an average year-over-year change of +16.36 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Equity [ROE] in the last five years was a gain of 33.21 percentage points in Q4 2024, against a drop of 28.69 percentage points in Q4 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at -37.04% (Q1 2026), -37.57% (Q4 2025) and -40.79% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | HCA Healthcare | 101.83 Bn | 101.28 Bn | - | - |
| 2 | Natera | 57.64 Bn | 53.32 Bn | 485.19 Mn | -10.70% |
| 3 | Quest Diagnostics | 26.88 Bn | 25.32 Bn | 1.03 Bn | 14.38% |
| 4 | Labcorp Holdings | 26.70 Bn | 24.47 Bn | 1.11 Bn | 11.58% |
| 5 | Tenet Healthcare | 21.80 Bn | 12.95 Bn | - | 47.84% |
| 6 | Guardant Health | 21.77 Bn | 17.83 Bn | 219.03 Mn | - |
| 7 | Encompass Health | 12.44 Bn | 12.90 Bn | - | 24.83% |
| 8 | Fresenius Medical Care AG | 12.41 Bn | 5.48 Bn | 1.52 Bn | 2.74% |
| 9 | BrightSpring Health Services | 12.02 Bn | 10.36 Bn | 492.75 Mn | 18.16% |
| 10 | Personalis | 1.68 Bn | 846.39 Mn | 4.74 Mn | -43.75% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -43.75% |
| Mar 31, 2026 | -37.04% |
| Dec 31, 2025 | -37.57% |
| Sep 30, 2025 | -40.79% |
| Jun 30, 2025 | -45.87% |
| Mar 31, 2025 | -40.98% |
| Dec 31, 2024 | -43.97% |
| Sep 30, 2024 | -65.54% |
| Jun 30, 2024 | -69.93% |
| Mar 31, 2024 | -74.04% |
| Dec 31, 2023 | -77.18% |
| Sep 30, 2023 | -68.92% |
| Jun 30, 2023 | -59.60% |
| Mar 31, 2023 | -55.26% |
| Dec 31, 2022 | -49.21% |
| Sep 30, 2022 | -40.41% |
| Jun 30, 2022 | -33.96% |
| Mar 31, 2022 | -27.15% |
| Dec 31, 2021 | -20.52% |
| Sep 30, 2021 | -17.58% |
API Access
Personalis Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=PSNL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "PSNL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=PSNL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();