Pliant Therapeutics (PLRX) EBITDA (2019 - 2026)
Pliant Therapeutics (PLRX) reported EBITDA of -$20.4 million for Q1 2026, up 63.84% year-over-year from -$12.4 million in Q1 2025, and up 13.8% quarter-over-quarter from -$23.6 million in Q4 2025.
Pliant Therapeutics (PLRX) EBITDA (2019 - 2026) Analysis & Trends
Pliant Therapeutics (PLRX) has 8 years of EBITDA data on file, last reported at -$20.4 million in Q1 2026.
- EBITDA for Q1 2026 came in at -$20.4 million, up 63.84% year-over-year; the trailing twelve-month figure through Mar 2026 was -$113.7 million (up 48.04% YoY), and the FY2025 annual result was -$149.7 million, up 28.83% from the prior year.
- EBITDA grew to -$20.4 million in Q1 2026 per PLRX's latest filing, from -$23.6 million in the prior quarter.
- Over five years, EBITDA peaked at -$20.4 million in Q1 2026 and troughed at -$56.3 million in Q1 2025.
- A 5-year average of -$39.1 million and a median of -$38.9 million in 2023 frame the typical range for EBITDA.
- The sharpest annual moves came in 2023 and 2026: EBITDA tumbled 41.02% in 2023, then jumped 63.84% in 2026.
- A 5-year view of EBITDA shows it stood at -$34.6 million in 2022, then declined by 12.42% to -$38.9 million in 2023, then retreated by 29.34% to -$50.3 million in 2024, then surged by 52.99% to -$23.6 million in 2025, then rose by 13.8% to -$20.4 million in 2026.
- Business Quant data shows PLRX's EBITDA at -$20.4 million in Q1 2026, -$23.6 million in Q4 2025, and -$26.3 million in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 719,706.53 Bn | 719,706.50 Bn | - | - |
| 2 | Belite Bio | 55,800.00 Bn | 55,800.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 18,182.30 Bn | 18,182.29 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 3,154.00 Bn | 3,153.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,844.30 Bn | 1,844.29 Bn | - | -14.44 Mn |
| 6 | Evaxion A | 1,567.96 Bn | 1,567.94 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 251.43 Bn | 251.42 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 112.56 Bn | 105.31 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 94.37 Bn | 94.37 Bn | - | -65.83 Mn |
| 10 | Pliant Therapeutics | 71.07 Mn | 71.07 Mn | - | -20.37 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -20.37 Mn |
| Dec 31, 2025 | -23.63 Mn |
| Sep 30, 2025 | -26.27 Mn |
| Jun 30, 2025 | -43.46 Mn |
| Mar 31, 2025 | -56.33 Mn |
| Dec 31, 2024 | -50.26 Mn |
| Sep 30, 2024 | -56.30 Mn |
| Jun 30, 2024 | -55.98 Mn |
| Mar 31, 2024 | -47.79 Mn |
| Dec 31, 2023 | -38.86 Mn |
| Sep 30, 2023 | -41.15 Mn |
| Jun 30, 2023 | -42.10 Mn |
| Mar 31, 2023 | -36.92 Mn |
| Dec 31, 2022 | -34.56 Mn |
| Sep 30, 2022 | -31.81 Mn |
| Jun 30, 2022 | -29.86 Mn |
| Mar 31, 2022 | -28.85 Mn |
| Dec 31, 2021 | -24.69 Mn |
| Sep 30, 2021 | -27.06 Mn |
| Jun 30, 2021 | -22.84 Mn |