NuCana (NCNA) Operating Expenses (2017 - 2025)
NuCana (NCNA) reported Operating Expenses of -$3.8 million for Q4 2025, down 132.18% on a YoY basis from $11.8 million in Q4 2024, and up 21.52% sequentially from -$4.8 million in Q3 2025.
NuCana (NCNA) Operating Expenses (2017 - 2025) Analysis & Trends
NuCana (NCNA) has 9 years of Operating Expenses data on file, last reported at -$3.8 million in Q4 2025.
- For the quarter ending Q4 2025, Operating Expenses fell 132.18% year-over-year to -$3.8 million; the trailing twelve-month figure through Dec 2025 stood at -$27.6 million (up 5.73% YoY), and the FY2025 full-year result was -$27.5 million, up 6.59% from the prior year.
- Operating Expenses grew to -$3.8 million in Q4 2025, from -$4.8 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $9.0 million in Q2 2021 to a low of -$17.3 million in Q4 2022.
- A 5-year average of -$8.6 million and a median of -$10.4 million in 2023 frame the typical range for Operating Expenses.
- Peak annual rise in Operating Expenses reached 196.88% in 2021, while the deepest fall reached 368.62% in 2021.
- Tracing NCNA's Operating Expenses over 5 years: stood at -$17.1 million in 2021, then slipped by 0.82% to -$17.3 million in 2022, then surged by 41.46% to -$10.1 million in 2023, then surged by 83.89% to -$1.6 million in 2024, then tumbled by 132.18% to -$3.8 million in 2025.
- Business Quant data shows NCNA's Operating Expenses at -$3.8 million in Q4 2025, -$4.8 million in Q3 2025, and -$15.5 million in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -28.01 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 1.10 Bn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.85 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 2.96 Bn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | 32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | -919.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 445.22 Mn |
| 10 | NuCana | 14.60 Bn | 14.60 Bn | - | -3.78 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -3.78 Mn |
| Sep 30, 2025 | -4.82 Mn |
| Jun 30, 2025 | -15.51 Mn |
| Mar 31, 2025 | -3.52 Mn |
| Dec 31, 2024 | -1.63 Mn |
| Sep 30, 2024 | -6.62 Mn |
| Jun 30, 2024 | -10.45 Mn |
| Mar 31, 2024 | -10.61 Mn |
| Dec 31, 2023 | -10.11 Mn |
| Sep 30, 2023 | -11.16 Mn |
| Jun 30, 2023 | -7.15 Mn |
| Mar 31, 2023 | -10.27 Mn |
| Dec 31, 2022 | -17.27 Mn |
| Sep 30, 2022 | -10.73 Mn |
| Jun 30, 2022 | 5.69 Mn |
| Mar 31, 2022 | -15.56 Mn |
| Dec 31, 2021 | -17.13 Mn |
| Sep 30, 2021 | -15.51 Mn |
| Jun 30, 2021 | 9.01 Mn |
| Mar 31, 2021 | -14.91 Mn |