NuCana (NCNA) Operating Expenses (2017 - 2025)
NuCana's (NCNA) quarterly Operating Expenses came in at -$3.8 million in Q4 2025, down 132.18% year-on-year from $11.8 million in Q4 2024, and up 21.52% quarter-over-quarter from -$4.8 million in Q3 2025.
NuCana (NCNA) Operating Expenses (2017 - 2025) Analysis & Trends
NuCana has disclosed Operating Expenses across 9 years of filings, most recently posting -$3.8 million for Q4 2025.
- Operating Expenses for Q4 2025 came in at -$3.8 million, down 132.18% year-over-year; the trailing twelve-month figure through Dec 2025 was -$8.7 million (up 29.01% YoY), and the FY2025 annual result was -$27.5 million, up 6.59% from the prior year.
- Operating Expenses came in at -$3.8 million for Q4 2025 at NuCana, up from -$4.8 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $9.0 million in Q2 2021 to a low of -$17.3 million in Q4 2022.
- The 5-year median for Operating Expenses is -$8.4 million (2024), against an average of -$6.3 million.
- Peak annual rise in Operating Expenses reached 196.88% in 2021, while the deepest fall reached 385.34% in 2021.
- NuCana's Operating Expenses stood at -$17.1 million in 2021, then dropped by 0.82% to -$17.3 million in 2022, then soared by 41.46% to -$10.1 million in 2023, then soared by 83.89% to -$1.6 million in 2024, then slumped by 132.18% to -$3.8 million in 2025.
- The last three Operating Expenses figures came in at -$3.8 million (Q4 2025), -$4.8 million (Q3 2025), and $3.4 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 723,416.35 Bn | 723,416.32 Bn | - | 4.33 Mn |
| 2 | Belite Bio | 57,340.00 Bn | 57,340.00 Bn | - | 32.68 Mn |
| 3 | Quantum Biopharma | 19,125.08 Bn | 19,125.08 Bn | - | 2.97 Mn |
| 4 | Legend Biotech | 3,262.00 Bn | 3,261.71 Bn | 242.10 Mn | -138.30 Mn |
| 5 | Akari Therapeutics | 1,789.67 Bn | 1,789.67 Bn | - | 15.76 Mn |
| 6 | Evaxion A | 1,480.39 Bn | 1,480.37 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 241.78 Bn | 241.78 Bn | - | 574,669.00 |
| 8 | Vertex Pharmaceuticals | 113.54 Bn | 106.29 Bn | 2.59 Bn | 1.85 Bn |
| 9 | Abivax | 94.26 Bn | 94.26 Bn | - | -67.40 Mn |
| 10 | NuCana | 29.13 Bn | 29.13 Bn | - | -3.78 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -3.78 Mn |
| Sep 30, 2025 | -4.82 Mn |
| Jun 30, 2025 | 3.44 Mn |
| Mar 31, 2025 | -3.52 Mn |
| Dec 31, 2024 | -1.63 Mn |
| Sep 30, 2024 | -6.62 Mn |
| Jun 30, 2024 | 6.64 Mn |
| Mar 31, 2024 | -10.61 Mn |
| Dec 31, 2023 | -10.11 Mn |
| Sep 30, 2023 | -11.16 Mn |
| Jun 30, 2023 | 2.76 Mn |
| Mar 31, 2023 | -10.27 Mn |
| Dec 31, 2022 | -17.27 Mn |
| Sep 30, 2022 | -10.73 Mn |
| Jun 30, 2022 | 5.69 Mn |
| Mar 31, 2022 | -15.56 Mn |
| Dec 31, 2021 | -17.13 Mn |
| Sep 30, 2021 | -15.51 Mn |
| Jun 30, 2021 | 9.01 Mn |
| Mar 31, 2021 | -14.91 Mn |