NuCana (NCNA) Operating Expenses (2017 - 2025)

NuCana (NCNA) reported Operating Expenses of -$3.8 million for Q4 2025, down 132.18% on a YoY basis from $11.8 million in Q4 2024, and up 21.52% sequentially from -$4.8 million in Q3 2025.

NuCana (NCNA) Operating Expenses (2017 - 2025) Analysis & Trends

NuCana (NCNA) has 9 years of Operating Expenses data on file, last reported at -$3.8 million in Q4 2025.

  • For the quarter ending Q4 2025, Operating Expenses fell 132.18% year-over-year to -$3.8 million; the trailing twelve-month figure through Dec 2025 stood at -$27.6 million (up 5.73% YoY), and the FY2025 full-year result was -$27.5 million, up 6.59% from the prior year.
  • Operating Expenses grew to -$3.8 million in Q4 2025, from -$4.8 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $9.0 million in Q2 2021 to a low of -$17.3 million in Q4 2022.
  • A 5-year average of -$8.6 million and a median of -$10.4 million in 2023 frame the typical range for Operating Expenses.
  • Peak annual rise in Operating Expenses reached 196.88% in 2021, while the deepest fall reached 368.62% in 2021.
  • Tracing NCNA's Operating Expenses over 5 years: stood at -$17.1 million in 2021, then slipped by 0.82% to -$17.3 million in 2022, then surged by 41.46% to -$10.1 million in 2023, then surged by 83.89% to -$1.6 million in 2024, then tumbled by 132.18% to -$3.8 million in 2025.
  • Business Quant data shows NCNA's Operating Expenses at -$3.8 million in Q4 2025, -$4.8 million in Q3 2025, and -$15.5 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 NuCana 14.60 Bn 14.60 Bn - -3.78 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -3.78 Mn
Sep 30, 2025 -4.82 Mn
Jun 30, 2025 -15.51 Mn
Mar 31, 2025 -3.52 Mn
Dec 31, 2024 -1.63 Mn
Sep 30, 2024 -6.62 Mn
Jun 30, 2024 -10.45 Mn
Mar 31, 2024 -10.61 Mn
Dec 31, 2023 -10.11 Mn
Sep 30, 2023 -11.16 Mn
Jun 30, 2023 -7.15 Mn
Mar 31, 2023 -10.27 Mn
Dec 31, 2022 -17.27 Mn
Sep 30, 2022 -10.73 Mn
Jun 30, 2022 5.69 Mn
Mar 31, 2022 -15.56 Mn
Dec 31, 2021 -17.13 Mn
Sep 30, 2021 -15.51 Mn
Jun 30, 2021 9.01 Mn
Mar 31, 2021 -14.91 Mn