NuCana (NCNA) Net Income (2017 - 2025)

NuCana (NCNA) reported Net Income of -$3.3 million for Q4 2025, down 294.39% on a YoY basis from $1.7 million in Q4 2024, and up 95.42% sequentially from -$72.1 million in Q3 2025.

NuCana (NCNA) Net Income (2017 - 2025) Analysis & Trends

NuCana (NCNA) has 9 years of Net Income data on file, last reported at -$3.3 million in Q4 2025.

  • For the quarter ending Q4 2025, Net Income fell 294.39% year-over-year to -$3.3 million; the trailing twelve-month figure through Dec 2025 stood at -$112.5 million (down 345.86% YoY), and the FY2025 full-year result was -$38.7 million, down 59.38% from the prior year.
  • Net Income climbed to -$3.3 million in Q4 2025, from -$72.1 million in the prior quarter.
  • In the past five years, Net Income ranged from a high of $40.0 million in Q2 2021 to a low of -$90.9 million in Q4 2021.
  • A 5-year average of -$12.1 million and a median of -$9.1 million in 2022 frame the typical range for Net Income.
  • Across the five-year window, Net Income surged 431.33% in 2021 and plunged 381.87% in 2023, its largest moves.
  • Tracing NCNA's Net Income over 5 years: stood at -$90.9 million in 2021, then surged by 75.84% to -$22.0 million in 2022, then soared by 56.73% to -$9.5 million in 2023, then jumped by 91.18% to -$838126.7 in 2024, then sank by 294.39% to -$3.3 million in 2025.
  • Business Quant data shows NCNA's Net Income at -$3.3 million in Q4 2025, -$72.1 million in Q3 2025, and -$33.0 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -37.09 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 227.36 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.31 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.03 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 727.20 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -26.94 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 362.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -453.82 Mn
10 Alnylam Pharmaceuticals 35.71 Bn 32.70 Bn 959.66 Mn 205.99 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -3.31 Mn
Sep 30, 2025 -72.13 Mn
Jun 30, 2025 -33.04 Mn
Mar 31, 2025 -4.00 Mn
Dec 31, 2024 -838,126.70
Sep 30, 2024 -41.81 Mn
Jun 30, 2024 26.09 Mn
Mar 31, 2024 -8.67 Mn
Dec 31, 2023 -9.50 Mn
Sep 30, 2023 -42.13 Mn
Jun 30, 2023 26.46 Mn
Mar 31, 2023 -9.56 Mn
Dec 31, 2022 -21.96 Mn
Sep 30, 2022 -8.74 Mn
Jun 30, 2022 26.07 Mn
Mar 31, 2022 -11.28 Mn
Dec 31, 2021 -90.89 Mn
Sep 30, 2021 11.09 Mn
Jun 30, 2021 39.99 Mn
Mar 31, 2021 -13.46 Mn