Mesoblast (MESO) Enterprise Value (2015 - 2025)

Mesoblast (MESO) reported Enterprise Value of -$130.0 million for Q4 2025, down 241.78% on a YoY basis from $91.7 million in Q4 2024, and up 19.55% sequentially from -$161.6 million in Q2 2025.

Mesoblast (MESO) Enterprise Value (2015 - 2025) Analysis & Trends

Mesoblast (MESO) has 11 years of Enterprise Value data on file, last reported at -$130.0 million in Q4 2025.

  • For the quarter ending Q4 2025, Enterprise Value fell 241.78% year-over-year to -$130.0 million; the trailing twelve-month figure through Dec 2025 stood at -$130.0 million (down 241.78% YoY), and the FY2025 full-year result was -$161.6 million, down 156.59% from the prior year.
  • Enterprise Value grew to -$130.0 million in Q4 2025, from -$161.6 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$38.0 million in Q4 2024 to a low of -$161.6 million in Q2 2025.
  • A 5-year average of -$92.4 million and a median of -$77.6 million in 2023 frame the typical range for Enterprise Value.
  • Across the five-year window, Enterprise Value jumped 55.84% in 2022 and plunged 241.78% in 2025, its largest moves.
  • Tracing MESO's Enterprise Value over 5 years: stood at -$94.8 million in 2021, then climbed by 28.71% to -$67.6 million in 2022, then fell by 14.69% to -$77.6 million in 2023, then surged by 50.96% to -$38.0 million in 2024, then sank by 241.78% to -$130.0 million in 2025.
  • Business Quant data shows MESO's Enterprise Value at -$130.0 million in Q4 2025, -$161.6 million in Q2 2025, and -$38.0 million in Q4 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -283.54 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - -32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -1.91 Bn
10 Mesoblast 2.08 Bn 1.95 Bn - -129.98 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -129.98 Mn
Jun 30, 2025 -161.16 Mn
Dec 31, 2024 -38.03 Mn
Jun 30, 2024 -62.96 Mn
Dec 31, 2023 -77.55 Mn
Jun 30, 2023 -71.32 Mn
Mar 31, 2023 -48.80 Mn
Dec 31, 2022 -67.62 Mn
Sep 30, 2022 -85.50 Mn
Jun 30, 2022 -60.45 Mn
Mar 31, 2022 -76.76 Mn
Dec 31, 2021 -94.85 Mn
Sep 30, 2021 -115.96 Mn
Jun 30, 2021 -136.88 Mn
Mar 31, 2021 -158.26 Mn
Dec 31, 2020 -77.53 Mn
Sep 30, 2020 -108.12 Mn
Jun 30, 2020 -129.33 Mn
Mar 31, 2020 -60.08 Mn
Dec 31, 2019 -81.35 Mn