Growth Metrics

Keros Therapeutics (KROS) Change in Cash (2019 - 2025)

Keros Therapeutics posted quarterly Change in Cash of -$406.1 million for Q4 2025, down 1488.37% year-on-year from $29.2 million in Q4 2024, and down 12567.21% on a QoQ basis from $3.3 million in Q3 2025.

Keros Therapeutics (KROS) has 7 years of Change in Cash data on file, last reported at -$406.1 million in Q4 2025.

  • For the quarter ending Q4 2025, Change in Cash fell 1488.37% year-over-year to -$406.1 million; the trailing twelve-month figure through Dec 2025 stood at -$272.5 million (down 218.99% YoY), and the FY2025 full-year result was -$272.5 million, down 218.99% from the prior year.
  • Change in Cash for Q4 2025 stood at -$406.1 million, down from $3.3 million in the prior quarter.
  • Across five years, Change in Cash topped out at $160.6 million in Q1 2025 and bottomed at -$406.1 million in Q4 2025.
  • The 5-year median for Change in Cash is $900500.0 (2022), against an average of $1.1 million.
  • The widest annual swing landed in 2023, when Change in Cash jumped 5071.22%; it then plunged 1488.37% in 2025.
  • A 5-year view of Change in Cash shows it stood at $8.7 million in 2021, then soared by 355.84% to $39.6 million in 2022, then increased by 9.17% to $43.3 million in 2023, then tumbled by 32.38% to $29.2 million in 2024, then slumped by 1488.37% to -$406.1 million in 2025.
  • The last three Change in Cash figures came in at -$406.1 million (Q4 2025), $3.3 million (Q3 2025), and -$30.3 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.44 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 623.00 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 417.10 Mn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -153.10 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 53.61 Mn
10 Keros Therapeutics 403.85 Mn 116.45 Mn - -406.06 Mn

Historic Data

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DateValue
Dec 31, 2025 -406.06 Mn
Sep 30, 2025 3.26 Mn
Jun 30, 2025 -30.33 Mn
Mar 31, 2025 160.61 Mn
Dec 31, 2024 29.25 Mn
Sep 30, 2024 125.06 Mn
Jun 30, 2024 -36.58 Mn
Mar 31, 2024 111.30 Mn
Dec 31, 2023 43.25 Mn
Sep 30, 2023 -34.25 Mn
Jun 30, 2023 -29.40 Mn
Mar 31, 2023 72.38 Mn
Dec 31, 2022 39.62 Mn
Sep 30, 2022 23.81 Mn
Jun 30, 2022 -12.97 Mn
Mar 31, 2022 -1.46 Mn
Dec 31, 2021 8.69 Mn
Sep 30, 2021 -14.55 Mn
Jun 30, 2021 -18.09 Mn
Mar 31, 2021 -10.67 Mn
Dec 31, 2020 132.07 Mn
Sep 30, 2020 -10.88 Mn
Jun 30, 2020 90.17 Mn
Mar 31, 2020 47.50 Mn
Dec 31, 2019 -5.51 Mn
Sep 30, 2019 -3.03 Mn
Jun 30, 2019 -5.20 Mn
Mar 31, 2019 -2.51 Mn