Ionis Pharmaceuticals IONS
NASDAQ IONS
$43.54 -0.46 (-1.05%)
At close: Oct 2, 2026 · 4:00 PM EDT

Ionis Pharmaceuticals (IONS) Return on Assets [ROA] (2010 - 2026)

Updated

Ionis Pharmaceuticals (IONS) reported Return on Assets [ROA] of -17.54% for Q2 2026, down 8.29 percentage points from -9.25% a year earlier and down 8.16 percentage points from the prior quarter.

Analysis

Ionis Pharmaceuticals (IONS) Return on Assets [ROA] (2010 - 2026) Analysis & Trends

For FY2025, Ionis Pharmaceuticals posted Return on Assets [ROA] of -11.69%, up 3.46 percentage points from FY2024.

  • Return on Assets [ROA] has a five-year change of +5.38 percentage points (FY2020 to FY2025).
  • By year, Return on Assets [ROA] came in at -15.15% in FY2024 (-1.88 pp), -13.26% in FY2023 (-2.78 pp), -10.48% in FY2022 (-9.34 pp) and -1.14% in FY2021 (+15.92 pp).
  • The Q2 2026 figure ranks as the lowest quarterly Return on Assets [ROA] since Q3 2021.
  • Year over year, Return on Assets [ROA] gained in five of the last eight quarters, with an average year-over-year change of +0.74 percentage points.
  • The high point for year-over-year Return on Assets [ROA] in five years was Q3 2022 (a gain of 25.09 percentage points); the low point was Q3 2021 (a drop of 27.38 percentage points).
  • Per Business Quant data, the three quarters before Q2 2026 came in at -9.38% (Q1 2026), -11.63% (Q4 2025) and -8.52% (Q3 2025).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROA (Qtr)
1 Eli Lilly 1,076.25 Bn 1,044.84 Bn 19.71 Bn 20.64%
2 Johnson & Johnson 617.18 Bn 535.70 Bn 17.26 Bn 10.47%
3 AbbVie 464.58 Bn 437.73 Bn 12.70 Bn 4.65%
4 Merck 356.04 Bn 310.47 Bn 12.21 Bn 2.45%
5 Novartis Ag 269.07 Bn 224.94 Bn 11.24 Bn 28.37%
6 Astrazeneca 243.21 Bn 216.77 Bn 12.86 Bn 9.10%
7 Amgen 217.88 Bn 173.28 Bn 7.24 Bn 9.29%
8 Gilead Sciences 179.62 Bn 153.74 Bn 6.22 Bn -6.13%
9 Pfizer 158.45 Bn 105.40 Bn 10.94 Bn 2.14%
10 Ionis Pharmaceuticals 7.21 Bn -1.68 Bn 265.21 Mn -17.54%
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -17.54%
Mar 31, 2026 -9.38%
Dec 31, 2025 -11.63%
Sep 30, 2025 -8.52%
Jun 30, 2025 -9.25%
Mar 31, 2025 -15.75%
Dec 31, 2024 -14.92%
Sep 30, 2024 -12.43%
Jun 30, 2024 -13.41%
Mar 31, 2024 -13.37%
Dec 31, 2023 -12.37%
Sep 30, 2023 -13.87%
Jun 30, 2023 -10.56%
Mar 31, 2023 -12.14%
Dec 31, 2022 -10.89%
Sep 30, 2022 0.30%
Jun 30, 2022 -1.13%
Mar 31, 2022 -0.15%
Dec 31, 2021 -1.14%
Sep 30, 2021 -24.79%
API Access

Ionis Pharmaceuticals Return on Assets [ROA] API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=IONS&period=max&api_key=YOUR_API_KEY