Growth Metrics

Ionis Pharmaceuticals (IONS) Gross Profit (2018 - 2025)

Historic Gross Profit for Ionis Pharmaceuticals (IONS) over the last 8 years, with Q3 2025 value amounting to $154.4 million.

  • Ionis Pharmaceuticals' Gross Profit rose 1630.07% to $154.4 million in Q3 2025 from the same period last year, while for Sep 2025 it was $781.1 million, marking a year-over-year decrease of 144.99%. This contributed to the annual value of $693.9 million for FY2024, which is 1086.57% down from last year.
  • As of Q3 2025, Ionis Pharmaceuticals' Gross Profit stood at $154.4 million, which was up 1630.07% from $273.8 million recorded in Q2 2025.
  • In the past 5 years, Ionis Pharmaceuticals' Gross Profit registered a high of $437.8 million during Q4 2021, and its lowest value of $109.0 million during Q1 2021.
  • Over the past 5 years, Ionis Pharmaceuticals' median Gross Profit value was $142.0 million (recorded in 2023), while the average stood at $179.1 million.
  • Per our database at Business Quant, Ionis Pharmaceuticals' Gross Profit soared by 112939.53% in 2021 and then tumbled by 6614.65% in 2022.
  • Ionis Pharmaceuticals' Gross Profit (Quarter) stood at $437.8 million in 2021, then tumbled by 66.15% to $148.2 million in 2022, then skyrocketed by 116.89% to $321.4 million in 2023, then tumbled by 30.7% to $222.7 million in 2024, then plummeted by 30.69% to $154.4 million in 2025.
  • Its Gross Profit stands at $154.4 million for Q3 2025, versus $273.8 million for Q2 2025 and $130.1 million for Q1 2025.