EXACT SCIENCES CORP (EXAS) Operating Margin (2010 - 2025)

Exact Sciences (EXAS) has reported Operating Margin for 16 consecutive years, with 9.4% the latest figure, recorded in Q4 2025.

• On a quarterly basis, Operating Margin rose 11343.0% year-over-year to 9.4% in Q4 2025; TTM through Dec 2025 was 6.35%, a 3166.0% increase from a year earlier, with the FY2025 full-year figure at 6.35%, up 3166.0% from the prior year.
• Operating Margin was 9.4% for Q4 2025 at Exact Sciences, down from 3.0% in the prior quarter.
• Over five years, Operating Margin peaked at 1.09% in Q3 2023 and troughed at 122.84% in Q4 2024.
• A 5-year average of 26.05% and a median of 15.16% in 2024 frame the typical range for Operating Margin.
• Across the five-year window, Operating Margin plunged 11235 bps in 2024 and surged 11343 bps in 2025, its largest moves.
• Over 5 years, Operating Margin stood at 46.74% in 2021, then soared by 54 bps to 21.5% in 2022, then soared by 51 bps to 10.49% in 2023, then tumbled by 1071 bps to 122.84% in 2024, then soared by 92 bps to 9.4% in 2025.
• The last three Operating Margin figures came in at 9.4% (Q4 2025), 3.0% (Q3 2025), and 0.26% (Q2 2025), per Business Quant data.