Esperion Therapeutics (ESPR) Operating Expenses (2012 - 2026)

Esperion Therapeutics (ESPR) posted Operating Expenses of $86.7 million for Q1 2026, up 166.46% on a QoQ basis from -$130.4 million in Q4 2025, and little changed year-over-year from $87.1 million in Q1 2025.

Esperion Therapeutics (ESPR) Operating Expenses (2012 - 2026) Analysis & Trends

Esperion Therapeutics' Operating Expenses history runs 15 years deep, the most recent figure standing at $86.7 million for Q1 2026.

  • Quarterly Operating Expenses changed 0.47% year-over-year to $86.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $128.8 million (down 56.99% YoY) and the FY2025 annual result came in at $129.2 million, down 53.5% from the prior year.
  • Operating Expenses was $86.7 million for Q1 2026 at Esperion Therapeutics, up from -$130.4 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $97.3 million in Q3 2025 and bottomed at -$130.4 million in Q4 2025.
  • A 5-year average of $60.0 million and a median of $71.2 million in 2022 frame the typical range for Operating Expenses.
  • Peak annual rise in Operating Expenses reached 43.76% in 2025, while the deepest fall reached 277.37% in 2025.
  • Esperion Therapeutics' Operating Expenses stood at $61.3 million in 2022, then climbed by 21.66% to $74.6 million in 2023, then dropped by 1.45% to $73.5 million in 2024, then sank by 277.37% to -$130.4 million in 2025, then jumped by 166.46% to $86.7 million in 2026.
  • Business Quant data shows ESPR's Operating Expenses at $86.7 million in Q1 2026, -$130.4 million in Q4 2025, and $97.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Haleon 87.22 Bn 85.35 Bn - -
2 Teva Pharmaceutical Industries 39.60 Bn 35.87 Bn 1.97 Bn 1.00 Bn
3 Zoetis 31.46 Bn 29.52 Bn 1.62 Bn 788.00 Mn
4 Takeda Pharmaceutical 26.49 Bn 22.44 Bn 4.39 Bn 12.58 Bn
5 United Therapeutics 23.03 Bn 20.88 Bn 648.10 Mn 455.70 Mn
6 Universe Pharmaceuticals 23.03 Bn -10.56 Bn - -
7 Viatris 20.90 Bn 19.09 Bn 1.16 Bn 1.24 Bn
8 Neurocrine Biosciences 17.50 Bn 16.19 Bn 800.70 Mn 621.10 Mn
9 Elanco Animal Health 12.33 Bn 11.91 Bn 785.00 Mn 494.00 Mn
10 Esperion Therapeutics 799.30 Mn 643.14 Mn 45.53 Mn 86.69 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 86.69 Mn
Dec 31, 2025 -130.43 Mn
Sep 30, 2025 97.27 Mn
Jun 30, 2025 75.29 Mn
Mar 31, 2025 87.09 Mn
Dec 31, 2024 73.53 Mn
Sep 30, 2024 67.66 Mn
Jun 30, 2024 71.26 Mn
Mar 31, 2024 65.47 Mn
Dec 31, 2023 74.62 Mn
Sep 30, 2023 61.50 Mn
Jun 30, 2023 62.84 Mn
Mar 31, 2023 72.93 Mn
Dec 31, 2022 61.33 Mn
Sep 30, 2022 60.60 Mn
Jun 30, 2022 71.22 Mn
Mar 31, 2022 61.83 Mn
Dec 31, 2021 71.03 Mn
Sep 30, 2021 70.15 Mn
Jun 30, 2021 73.19 Mn