Esperion Therapeutics, Inc. (ESPR) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

6,085,537Shares held by institutions

$16,004,962Value of institutional holdings

49.14%Institutional ownership %

0.01%Shares Changed QoQ

162No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Esperion Therapeutics, Inc. (NASDAQ:ESPR) appears in 195 institutional 13F filings for the quarter ending December 2025.

They owned 75.3% of outstanding stock in December 2025, up from 54.4% the prior quarter.
They increased total shares held in ESPR by 44.43% quarter over quarter, and investors in Esperion Therapeutics increased 4.28% from a year ago.
Among the 195 funds, 122 bought more Esperion Therapeutics shares, 35 sold down, and 38 held their ground.
In total, institutional investors held 151.08Mn shares in Esperion Therapeutics as of December 2025, up by 46.47Mn shares quarter on quarter, and up 11.46Mn shares year over year.
BlackRock, Inc. is the top holder of Esperion Therapeutics as of December 31, 2025, with 17.68Mn shares representing 8.81% of outstanding stock.
The biggest buyers of Esperion Therapeutics for the quarter ending December 2025 included D. E. Shaw & Co., Inc. (6.69Mn), ORBIMED ADVISORS LLC (5.97Mn), Eversept Partners, LP (3.85Mn), MILLENNIUM MANAGEMENT LLC (2.96Mn), MARSHALL WACE, LLP (2.95Mn).
Leading sellers of Esperion Therapeutics shares for the quarter ending December 2025 were PenderFund Capital Management Ltd. (2.28Mn), UBS Group AG (932.96K), Jpmorgan Chase & Co (925.92K), Royal Bank Of Canada (900.66K), JANE STREET GROUP, LLC (872.32K).
Per Business Quant, the top 10 investors in ESPR for the quarter ending December 2025 include BlackRock, Inc. (17.68Mn), VANGUARD GROUP INC (14.95Mn), Two Seas Capital LP (11.9Mn), WASATCH ADVISORS LP (9.45Mn), D. E. Shaw & Co., Inc. (6.9Mn), ORBIMED ADVISORS LLC (5.97Mn), State Street Corp (5.93Mn), GEODE CAPITAL MANAGEMENT, LLC (5.74Mn), MARSHALL WACE, LLP (5.47Mn), TWO SIGMA INVESTMENTS, LP (4.74Mn).

195 Institutional Holders

6,085,537 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	2,848,410	19.20%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	2,853,005	23.59%	$0.00
Two Seas Capital LP	31 Dec, 2025	2,152,797	22.08%	$0.00
Barclays Plc	31 Dec, 2025	-201,941	-31.30%	$0.00
WASATCH ADVISORS LP	31 Dec, 2025	2,383,902	33.76%	$0.00
PenderFund Capital Management Ltd.	31 Dec, 2025	-2,284,593	-34.22%	$0.00
HSBC HOLDINGS PLC	31 Dec, 2025	37,020	0.00%	$0.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	6,694,850	3,208.91%	$0.00
AIGH Capital Management LLC	31 Dec, 2025	1,000,000	33.33%	$0.00
Rockefeller Capital Management L.P.	31 Dec, 2025	1,440	0.00%	$0.00
ORBIMED ADVISORS LLC	31 Dec, 2025	5,965,498	0.00%	$0.00
Eversept Partners, LP	31 Dec, 2025	3,851,133	0.00%	$0.00
State Street Corp	31 Dec, 2025	1,451,462	32.41%	$0.00
Nuveen, LLC	31 Dec, 2025	-98,956	-2.67%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	986,255	20.76%	$0.00
Walleye Capital LLC	31 Dec, 2025	1,250,025	391.62%	$0.00
MARSHALL WACE, LLP	31 Dec, 2025	2,950,172	117.00%	$0.00
Velan Capital Investment Management LP	31 Dec, 2025	1,210,000	0.00%	$0.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	2,503,464	111.83%	$0.00
Burkehill Global Management, LP	31 Dec, 2025	400,000	0.00%	$0.00

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