Clene (CLNN) Return on Sales (2020 - 2025)

Clene's Return on Sales history runs 6 years deep, the most recent figure standing at 1.21% for Q4 2025.

• In Q4 2025, Return on Sales fell 402.0% year-over-year to 1.21%; the TTM figure through Dec 2025 stood at 1.28% (down 182.0% YoY), while the FY2025 annual figure was 1.31%, down 130.0% from the prior year.
• Return on Sales was 1.21% for Q4 2025 at Clene, up from 5.84% in the prior quarter.
• In the past five years, Return on Sales ranged from a high of 2.81% in Q4 2024 to a low of 5.84% in Q3 2025.
• Historically, Return on Sales has averaged 0.8% across 5 years, with a median of 0.26% in 2022.
• Biggest YoY gain for Return on Sales was 630 bps in 2021; the steepest drop was 668 bps in 2021.
• A 5-year view of Return on Sales shows it stood at 0.27% in 2021, then surged by 260 bps to 0.97% in 2022, then plunged by 101 bps to 0.01% in 2023, then soared by 23622 bps to 2.81% in 2024, then plunged by 143 bps to 1.21% in 2025.
• The last three Return on Sales figures came in at 1.21% (Q4 2025), 5.84% (Q3 2025), and 2.75% (Q2 2025), per Business Quant data.