Clene (CLNN) Return on Capital Employed (2021 - 2025)

Clene's Return on Capital Employed history runs 5 years deep, the most recent figure standing at 243.76% for Q4 2025.

• On a quarterly basis, Return on Capital Employed fell 7114.0% year-over-year to 243.76% in Q4 2025; TTM through Dec 2025 was 243.76%, a 7114.0% decrease from a year earlier, with the FY2025 full-year figure at 193.03%, down 8101.0% from the prior year.
• Return on Capital Employed eased to 243.76% in Q4 2025 per CLNN's latest filing, from 173.96% in the prior quarter.
• Across five years, Return on Capital Employed topped out at 47.04% in Q1 2021 and bottomed at 283.01% in Q3 2024.
• The 5-year median for Return on Capital Employed is 156.2% (2022), against an average of 146.25%.
• Across the five-year window, Return on Capital Employed plunged 19665 bps in 2024 and jumped 10904 bps in 2025, its largest moves.
• Year by year, Return on Capital Employed stood at 80.62% in 2021, then sank by 127 bps to 183.31% in 2022, then gained by 29 bps to 130.15% in 2023, then tumbled by 33 bps to 172.62% in 2024, then sank by 41 bps to 243.76% in 2025.
• Per Business Quant, the three latest CLNN Return on Capital Employed figures stand at 243.76% (Q4 2025), 173.96% (Q3 2025), and 163.62% (Q2 2025).