CASI Pharmaceuticals (CASIF) Net Margin (2022 - 2025)
CASI Pharmaceuticals' Net Margin was -1157.31% in Q4 2025, down 1047.43 percentage points from -109.88% a year earlier and down 802.38 percentage points from the prior quarter.
CASI Pharmaceuticals (CASIF) Net Margin (2022 - 2025) Analysis & Trends
For FY2025, Net Margin at CASI Pharmaceuticals came in at -232.08%, down 92.50 percentage points from FY2024.
- Net Margin shows a five-year change of +98.02 percentage points (FY2020 to FY2025).
- In earlier years, Net Margin was -139.58% in FY2024 (-50.32 pp), -89.26% in FY2023 (+27.91 pp), -117.18% in FY2022 (+9.34 pp) and -126.51% in FY2021 (+203.59 pp).
- The Q4 2025 figure marks the lowest quarterly Net Margin in data going back to Q1 2022.
- Compared with a year earlier, Net Margin has declined for three straight quarters, with an average year-over-year change of -206.30 percentage points over the last eight quarters.
- The best year-over-year quarter for Net Margin over five years was Q1 2025 (a gain of 104.40 percentage points); the worst was Q4 2025 (a drop of 1047.43 percentage points).
- Per Business Quant data, CASIF's Net Margin in the three quarters before Q4 2025 was -354.93% (Q3 2025), -320.65% (Q2 2025) and -172.28% (Q1 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 26.44% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 0.83% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 24.24% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 28.01% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 20.69% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 37.28% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 29.27% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 19.55% |
| 10 | CASI Pharmaceuticals | 2.06 Mn | -18.77 Mn | - | - |
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -173.87% |
| Sep 30, 2025 | -354.93% |
| Jun 30, 2025 | -320.65% |
| Mar 31, 2025 | -172.28% |
| Dec 31, 2024 | -109.88% |
| Sep 30, 2024 | -108.34% |
| Jun 30, 2024 | -182.99% |
| Mar 31, 2024 | -276.68% |
| Dec 31, 2023 | -109.08% |
| Sep 30, 2023 | -59.23% |
| Jun 30, 2023 | -106.50% |
| Mar 31, 2023 | -79.98% |
| Dec 31, 2022 | -179.11% |
| Sep 30, 2022 | -59.49% |
| Jun 30, 2022 | -107.71% |
| Mar 31, 2022 | -99.46% |
CASI Pharmaceuticals Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=CASIF&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "CASIF", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=CASIF&period=max&api_key=YOUR_API_KEY");
const data = await res.json();