CASI Pharmaceuticals (CASIF) Net Margin (2022 - 2025)
CASI Pharmaceuticals' Net Margin was -665439421.42% in Q4 2025, down 371504297.79 percentage points from -293935123.63% a year earlier and down 665439066.49 percentage points from the prior quarter.
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Analysis
CASI Pharmaceuticals (CASIF) Net Margin (2022 - 2025) Analysis & Trends
For FY2025, Net Margin at CASI Pharmaceuticals came in at -232029741.21%, down 94460970.84 percentage points from FY2024.
- Net Margin shows a five-year change of -232029416.23 percentage points (FY2020 to FY2025).
- In earlier years, Net Margin was -137568770.37% in FY2024 (-60060569.77 pp), -77508200.60% in FY2023 (+15880366.22 pp), -93388566.82% in FY2022 (-93388443.00 pp) and -123.82% in FY2021 (+201.16 pp).
- The Q4 2025 figure marks the lowest quarterly Net Margin in data going back to Q1 2022.
- Compared with a year earlier, Net Margin has declined for three straight quarters, with an average year-over-year change of -35429456.43 percentage points over the last eight quarters.
- The best year-over-year quarter for Net Margin over five years was Q4 2024 (a gain of 88069248.47 percentage points); the worst was Q4 2025 (a drop of 371504297.79 percentage points).
- Per Business Quant data, CASIF's Net Margin in the three quarters before Q4 2025 was -354.93% (Q3 2025), -320.65% (Q2 2025) and -172.28% (Q1 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | CASI Pharmaceuticals | 2.67 Mn | -18.15 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -665,439,421.42% |
| Sep 30, 2025 | -354.93% |
| Jun 30, 2025 | -320.65% |
| Mar 31, 2025 | -172.28% |
| Dec 31, 2024 | -293,935,123.63% |
| Sep 30, 2024 | -108.34% |
| Jun 30, 2024 | -182.99% |
| Mar 31, 2024 | -276.68% |
| Dec 31, 2023 | -382,004,372.10% |
| Sep 30, 2023 | -59.23% |
| Jun 30, 2023 | -106.50% |
| Mar 31, 2023 | -79.98% |
| Dec 31, 2022 | -263,824,538.42% |
| Sep 30, 2022 | -59.49% |
| Jun 30, 2022 | -107.71% |
| Mar 31, 2022 | -99.46% |
API Access
CASI Pharmaceuticals Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=CASIF&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "CASIF", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=CASIF&period=max&api_key=YOUR_API_KEY");
const data = await res.json();