Annovis Bio (ANVS) Return on Equity [ROE] (2020 - 2026)
Annovis Bio (ANVS) reported Return on Equity [ROE] of -408.27% for Q1 2026, down 226.11 percentage points from -182.15% a year earlier and down 214.86 percentage points from the prior quarter.
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Analysis
Annovis Bio (ANVS) Return on Equity [ROE] (2020 - 2026) Analysis & Trends
For FY2025, Annovis Bio posted Return on Equity [ROE] of -221.73%, up 3165.75 percentage points from FY2024.
- Return on Equity [ROE] has a four-year change of -166.05 percentage points (FY2021 to FY2025).
- By year, Return on Equity [ROE] came in at -3387.48% in FY2024 (-2841.08 pp), -546.40% in FY2023 (-476.83 pp), -69.57% in FY2022 (-13.89 pp) and -55.68% in FY2021.
- The Q1 2026 figure ranks as the lowest quarterly Return on Equity [ROE] since Q3 2024.
- Year over year, Return on Equity [ROE] gained in two of the last four quarters, with an average year-over-year change of +7.21 percentage points.
- The high point for year-over-year Return on Equity [ROE] in five years was Q3 2025 (a gain of 1375.43 percentage points); the low point was Q3 2024 (a drop of 1236.65 percentage points).
- Per Business Quant data, the three quarters before Q1 2026 came in at -193.41% (Q4 2025), -165.71% (Q3 2025) and -148.38% (Q2 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | 82.09% |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | 25.32% |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | - |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | 7.21% |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | 84.40% |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | 21.39% |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | 83.75% |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -18.38% |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 4.97% |
| 10 | Annovis Bio | 49.85 Mn | 49.85 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Mar 31, 2026 | -408.27% |
| Dec 31, 2025 | -193.41% |
| Sep 30, 2025 | -165.71% |
| Jun 30, 2025 | -148.38% |
| Mar 31, 2025 | -182.15% |
| Dec 31, 2024 | -309.56% |
| Sep 30, 2024 | -1,541.15% |
| Sep 30, 2023 | -304.49% |
| Jun 30, 2023 | -163.57% |
| Mar 31, 2023 | -123.12% |
| Dec 31, 2022 | -80.52% |
| Sep 30, 2022 | -64.20% |
| Jun 30, 2022 | -49.00% |
| Mar 31, 2022 | -37.90% |
| Dec 31, 2021 | -31.83% |
| Sep 30, 2021 | -21.60% |
| Jun 30, 2021 | -31.84% |
| Mar 31, 2021 | -138.05% |
| Dec 31, 2020 | -65.56% |
| Sep 30, 2020 | -42.52% |
API Access
Annovis Bio Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=ANVS&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "ANVS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=ANVS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();