Growth Metrics

Alx Oncology Holdings (ALXO) Operating Income (2019 - 2026)

Alx Oncology Holdings recorded quarterly Operating Income of -$19.0 million in Q1 2026, up 17.61% quarter-over-quarter from -$23.0 million in Q4 2025, and up 40.4% year-over-year from -$13.5 million in Q1 2025.

Alx Oncology Holdings' Operating Income history runs 8 years deep, the most recent figure standing at -$19.0 million for Q1 2026.

  • In Q1 2026, Operating Income rose 40.4% year-over-year to -$19.0 million; the TTM figure through Mar 2026 stood at -$91.2 million (up 33.22% YoY), while the FY2025 annual figure was -$104.0 million, up 26.99% from the prior year.
  • Operating Income came in at -$19.0 million for Q1 2026 at Alx Oncology Holdings, up from -$23.0 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $88.5 million in Q4 2023 to a low of -$53.3 million in Q3 2023.
  • A 5-year average of -$25.1 million and a median of -$32.2 million in 2023 frame the typical range for Operating Income.
  • Across the five-year window, Operating Income soared 374.64% in 2023 and plunged 134.6% in 2024, its largest moves.
  • Alx Oncology Holdings' Operating Income stood at -$32.2 million in 2022, then soared by 374.64% to $88.5 million in 2023, then slumped by 134.6% to -$30.6 million in 2024, then gained by 24.8% to -$23.0 million in 2025, then gained by 17.61% to -$19.0 million in 2026.
  • According to Business Quant data, Operating Income over the past three periods registered -$19.0 million, -$23.0 million, and -$22.5 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 268.64 Mn
10 Alx Oncology Holdings 189.80 Mn 49.48 Mn - -18.97 Mn

Historic Data

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DateValue
Mar 31, 2026 -18.97 Mn
Dec 31, 2025 -23.02 Mn
Sep 30, 2025 -22.53 Mn
Jun 30, 2025 -26.65 Mn
Mar 31, 2025 -31.82 Mn
Dec 31, 2024 -30.61 Mn
Sep 30, 2024 -32.57 Mn
Jun 30, 2024 -41.53 Mn
Mar 31, 2024 -37.76 Mn
Dec 31, 2023 88.49 Mn
Sep 30, 2023 -53.28 Mn
Jun 30, 2023 -36.78 Mn
Mar 31, 2023 -32.20 Mn
Dec 31, 2022 -32.22 Mn
Sep 30, 2022 -36.68 Mn
Jun 30, 2022 -33.79 Mn
Mar 31, 2022 -24.75 Mn
Dec 31, 2021 -28.47 Mn
Sep 30, 2021 -24.58 Mn
Jun 30, 2021 -16.30 Mn
Mar 31, 2021 -14.21 Mn
Dec 31, 2020 16.28 Mn
Sep 30, 2020 -9.81 Mn
Jun 30, 2020 -10.79 Mn
Mar 31, 2020 -5.24 Mn
Dec 31, 2019 -7.73 Mn
Sep 30, 2019 -3.03 Mn
Jun 30, 2019 -4.19 Mn