Agios Pharmaceuticals (AGIO) Free Cash Flow (2012 - 2026)

Agios Pharmaceuticals (AGIO) posted Free Cash Flow of -$119.7 million for Q1 2026, down 24.47% on a QoQ basis from -$96.2 million in Q4 2025, and down 6.62% year-over-year from -$128.2 million in Q1 2025.

Agios Pharmaceuticals (AGIO) Free Cash Flow (2012 - 2026) Analysis & Trends

Agios Pharmaceuticals' Free Cash Flow history runs 15 years deep, the most recent figure standing at -$119.7 million for Q1 2026.

  • Quarterly Free Cash Flow fell 6.62% year-over-year to -$119.7 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$380.7 million (up 5.75% YoY) and the FY2025 annual result came in at -$373.3 million, up 4.67% from the prior year.
  • Free Cash Flow was -$119.7 million for Q1 2026 at Agios Pharmaceuticals, down from -$96.2 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$61.6 million in Q4 2022 and bottomed at -$134.8 million in Q4 2024.
  • A 5-year average of -$87.7 million and a median of -$84.2 million in 2024 frame the typical range for Free Cash Flow.
  • Annual changes were most pronounced in 2022 — Free Cash Flow jumped 53.92% — and 2024, when it plunged 83.46%.
  • Agios Pharmaceuticals' Free Cash Flow stood at -$61.6 million in 2022, then dropped by 19.37% to -$73.5 million in 2023, then plunged by 83.46% to -$134.8 million in 2024, then rose by 28.66% to -$96.2 million in 2025, then dropped by 24.47% to -$119.7 million in 2026.
  • Business Quant data shows AGIO's Free Cash Flow at -$119.7 million in Q1 2026, -$96.2 million in Q4 2025, and -$86.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -19.58 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 158.09 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.53 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -354.95 Mn
10 Agios Pharmaceuticals 2.13 Bn 2.13 Bn 19.43 Mn -119.69 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -119.69 Mn
Mar 31, 2026 -119.69 Mn
Dec 31, 2025 -96.16 Mn
Dec 31, 2025 -96.16 Mn
Sep 30, 2025 -86.85 Mn
Sep 30, 2025 -86.85 Mn
Jun 30, 2025 -78.00 Mn
Jun 30, 2025 -78.00 Mn
Mar 31, 2025 -112.26 Mn
Mar 31, 2025 -112.26 Mn
Dec 31, 2024 -134.79 Mn
Dec 31, 2024 -134.79 Mn
Sep 30, 2024 -84.24 Mn
Sep 30, 2024 -84.24 Mn
Jun 30, 2024 -72.63 Mn
Jun 30, 2024 -72.63 Mn
Mar 31, 2024 -99.87 Mn
Mar 31, 2024 -99.87 Mn
Dec 31, 2023 -73.47 Mn
Dec 31, 2023 -73.47 Mn