Agios Pharmaceuticals (AGIO) EBIT Margin (2012 - 2026)

Agios Pharmaceuticals (AGIO) posted EBIT Margin of 530.34% for Q1 2026, up 12.9% on a QoQ basis from 608.89% in Q4 2025, and up 69163.0% year-over-year from N/an in Q1 2025.

Agios Pharmaceuticals (AGIO) EBIT Margin (2012 - 2026) Analysis & Trends

Agios Pharmaceuticals' EBIT Margin history runs 14 years deep, the most recent figure standing at 530.34% for Q1 2026.

  • Quarterly EBIT Margin rose 69163.0% year-over-year to 530.34% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 719.97% (up 46889.0% YoY) and the FY2025 annual result came in at 873.87%, up 29260.0% from the prior year.
  • EBIT Margin was 530.34% for Q1 2026 at Agios Pharmaceuticals, up from 608.89% in the prior quarter.
  • Across five years, EBIT Margin topped out at 530.34% in Q1 2026 and bottomed at 12156.85% in Q1 2022.
  • A 5-year average of 1977.81% and a median of 1228.29% in 2024 frame the typical range for EBIT Margin.
  • Annual changes were most pronounced in 2023 — EBIT Margin surged 1054136 bps — and 2025, when it tumbled 9763 bps.
  • Agios Pharmaceuticals' EBIT Margin stood at 2300.97% in 2022, then surged by 35 bps to 1496.23% in 2023, then grew by 22 bps to 1165.3% in 2024, then soared by 48 bps to 608.89% in 2025, then advanced by 13 bps to 530.34% in 2026.
  • Business Quant data shows AGIO's EBIT Margin at 530.34% in Q1 2026, 608.89% in Q4 2025, and 907.37% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 16.51%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 17.83%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 31.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Agios Pharmaceuticals 2.13 Bn 2.13 Bn 19.43 Mn -530.34%

Historic Data

Download Data
DateValue
Mar 31, 2026 -530.34%
Dec 31, 2025 -608.89%
Sep 30, 2025 -907.37%
Jun 30, 2025 -1,020.12%
Mar 31, 2025 -1,221.97%
Dec 31, 2024 -1,165.30%
Sep 30, 2024 -1,146.93%
Jun 30, 2024 -1,228.29%
Mar 31, 2024 -1,124.34%
Dec 31, 2023 -1,496.23%
Sep 30, 2023 -1,363.66%
Jun 30, 2023 -1,396.01%
Mar 31, 2023 -1,615.49%
Dec 31, 2022 -2,300.97%
Sep 30, 2022 -2,590.73%
Jun 30, 2022 -1,749.19%
Mar 31, 2022 -12,156.85%
Dec 31, 2020 -209.86%
Sep 30, 2020 -231.34%
Jun 30, 2020 -222.95%