Actuate Therapeutics ACTU
NASDAQ ACTU
$1.27 +0.04 (+3.25%)
At close: Aug 21, 2026 · 4:00 PM EDT

Actuate Therapeutics (ACTU) Profit After Tax (2023 - 2025)

Actuate Therapeutics (ACTU) posted quarterly Profit After Tax of -$4.6 million for Q4 2025, up 29.35% year-over-year from -$3.5 million in Q4 2024, and up 15.78% quarter-over-quarter from -$5.4 million in Q3 2025.

Actuate Therapeutics (ACTU) Profit After Tax (2023 - 2025) Analysis & Trends

Actuate Therapeutics (ACTU) has reported Profit After Tax for 3 consecutive years, with -$4.6 million the latest figure, recorded in Q4 2025.

  • In Q4 2025, Profit After Tax rose 29.35% year-over-year to -$4.6 million; the TTM figure through Dec 2025 stood at -$22.2 million (up 18.54% YoY), while the FY2025 annual figure was -$22.2 million, up 18.54% from the prior year.
  • Profit After Tax advanced to -$4.6 million in Q4 2025 per ACTU's latest filing, from -$5.4 million in the prior quarter.
  • Across five years, Profit After Tax topped out at -$4.6 million in Q4 2025 and bottomed at -$8.3 million in Q1 2024.
  • Historically, Profit After Tax has averaged -$6.3 million across 3 years, with a median of -$6.3 million in 2025.
  • Annual changes were most pronounced in 2024 — Profit After Tax decreased 18.97% — and 2025, when it grew 29.35%.
  • Actuate Therapeutics' Profit After Tax stood at -$7.6 million in 2023, then increased by 15.32% to -$6.4 million in 2024, then advanced by 29.35% to -$4.6 million in 2025.
  • Business Quant data shows ACTU's Profit After Tax at -$4.6 million in Q4 2025, -$5.4 million in Q3 2025, and -$5.9 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn 472.00 Mn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -782.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 237.01 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 164.49 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn -355.03 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -16.62 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 81.49 Mn
10 Actuate Therapeutics 30.08 Mn 30.08 Mn - -4.87 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -4.55 Mn
Sep 30, 2025 -5.41 Mn
Jun 30, 2025 -5.95 Mn
Mar 31, 2025 -6.32 Mn
Dec 31, 2024 -6.45 Mn
Sep 30, 2024 -5.97 Mn
Jun 30, 2024 -6.57 Mn
Mar 31, 2024 -8.30 Mn
Dec 31, 2023 -7.61 Mn
Sep 30, 2023 -6.34 Mn
Jun 30, 2023 -5.52 Mn