NXTS vs ROIV vs VRTX Stock Comparison

Nexentis Technologies, Roivant Sciences and Vertex Pharmaceuticals Prices as of Oct 26, 2026 Peers: Industry group
ROIV Roivant Sciences Ltd.
$36.05 +0.7% 1M +97.9% 1Y
Market cap
$25.99B
P/E
–
Revenue (TTM)
$7.53M
Div. yield
–
Biotechnology Healthcare
2 wins

Head to Head

7 decided of 12

Vertex Pharmaceuticals leads on 5 of the 12 questions below (Vertex Pharmaceuticals 5, Roivant Sciences 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionNXTSROIVVRTXLeader
Larger companyMarket capitalisation $433.53K $25.99B $130.22B VRTX
Cheaper on earningsLower P/E, profitable companies only 0.0x -97.6x 29.6x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 28.4x –
Faster revenue growthRevenue growth, trailing twelve months — -67.6% +10.2% VRTX
More profitableNet margin, trailing twelve months — -3,535.0% 35.0% VRTX
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA 1.6x — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -97.9% +97.9% +22.8% ROIV
Better 5-year returnAnnualised price return, 5 years -86.1%/yr +36.1%/yr +23.4%/yr ROIV
Less volatileAnnualised volatility, 1 year 169.1% 45.3% 29.0% VRTX
Higher overall scoreMean of the five percentile scores vs peers 32/100 65/100 76/100 VRTX

Percentile Scorecard

NXTSROIVVRTX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisNXTSROIVVRTX
Valuation – 64 #229 of 626 80 #124 of 626
Growth 13 #526 of 604 49 #308 of 604 60 #245 of 604
Profitability 40 #333 of 555 30 #387 of 555 95 #31 of 555
Financial Health 44 #372 of 658 93 #47 of 658 53 #308 of 658
Shareholder Returns – 91 #36 of 368 93 #27 of 368
Overall 32 65 76
  • NXTS ranked among 673 companies in Pharmaceuticals and Biotechnology
  • ROIV ranked among 673 companies in Pharmaceuticals and Biotechnology
  • VRTX ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodNXTSROIVVRTXSPY
1 month -61.9%+0.7%-1.7% -0.8%
3 months -66.5%+3.8%+8.0% +3.5%
6 months -88.4%+29.4%+21.5% +7.0%
Year to date -95.2%+66.1%+14.1% +12.2%
1 year -97.9%+97.9%+22.8% +13.0%
3 years -99.9%+330.2%+45.7% +86.3%
3 years, per year -89.6%+62.7%+13.4% +23.1%
5 years -100.0%+365.8%+186.0% +68.6%
5 years, per year -86.1%+36.1%+23.4% +11.0%
10 years -100.0%—+557.5% +258.0%
10 years, per year -66.6%—+20.7% +13.6%

Risk

MeasureNXTSROIVVRTXSPY
Volatility, 1Y 169.1%45.3%29.0% 12.7%
Downside volatility, 1Y 153.3%32.6%25.8% 12.7%
Beta vs S&P 500, 1Y 2.310.970.49 1.00
Return / volatility, 1Y -0.582.160.79 1.02
Max drawdown, 5Y -100.0%-79.2%-29.1% -25.4%
From 52-week high -97.8%-13.8%-7.3% -1.8%
52-week high $26.04$41.81$557.96 $779.14
52-week low $0.53$18.41$409.47 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleNXTSROIVVRTX
P/E now vs peer median 0.0xmedian 17.1x -97.6xmedian 17.1x 29.8xmedian 17.1x
P/S now vs peer median —median 8.8x 3,459xmedian 8.8x 10.4xmedian 8.8x
EV/EBITDA now vs peer median 1.5xmedian 17.1x -37.4xmedian 17.1x 24.7xmedian 17.1x
P/FCF now vs peer median —median 18.0x -31.7xmedian 18.0x 34.5xmedian 18.0x
P/B now vs peer median 0.2xmedian 2.1x 5.3xmedian 2.1x 6.5xmedian 2.1x
PEG now vs peer median 0.00median 0.31 -2.88median 0.31 2.94median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsNXTSROIVVRTX
Revenue – $7.53M $12.59B
Gross profit – $6.12M $10.82B
Operating income -$5.28M -$596.14M $4.78B
Net income -$14.06M -$414.60M $4.41B
Free cash flow – -$821.06M $3.80B
R&D $532.00K $730.91M $3.91B
EPS (diluted) $-17.10 $-0.37 $17.26
Cash & equivalents $7.62M $1.25B $6.14B
Total debt $3.22M – –
Shares (diluted) 816.14K 720.78M 255.20M
Enterprise value -$22.21M $8.94B $102.22B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricNXTSROIVVRTX
P/E 0.0x -97.6x 29.8x
P/FCF – -31.7x 34.5x
P/Operating cash flow – -31.9x 30.5x
P/S – 3,459x 10.4x
P/B 0.2x 5.3x 6.5x
P/Tangible book -0.2x 5.3x 6.6x
EV/EBITDA 1.5x -37.4x 24.7x
EV/EBIT 1.5x -37.3x 25.8x
EV/Revenue – 2,949x 9.8x
EV/FCF – -27.1x 32.5x
EV/Operating cash flow – -27.2x 28.7x
PEG (3Y EPS CAGR) 0.00 -2.88 2.94

Growth

14 metrics
MetricNXTSROIVVRTX
Revenue growth (1Y) – -67.6% 10.2%
Revenue CAGR (3Y) – -46.4% 9.8%
Gross profit growth (1Y) – -72.7% 10.1%
Gross profit CAGR (3Y) – -47.9% 9.0%
Operating income growth (1Y) -7.7% 49.7% 21.8%
Operating income CAGR (3Y) 3.0% 12.9% 6.4%
Net income growth (1Y) -48.2% 34.9% 21.1%
Net income CAGR (3Y) -35.8% 26.5% 9.4%
EPS growth (1Y) -567.8% 48.8% 22.9%
EPS CAGR (3Y) -45.2% 33.9% 10.1%
Operating cash flow growth (1Y) – 4.1% 11.6%
Operating cash flow CAGR (3Y) – 1.0% 1.8%
Free cash flow growth (1Y) – 4.4% 8.5%
Free cash flow CAGR (3Y) – 1.0% -0.7%

Profitability

14 metrics
MetricNXTSROIVVRTX
Gross margin – 81.2% 86.0%
EBITDA margin – -7,877% 39.7%
Operating margin – -7,915% 38.0%
Pretax margin – -3,849% 41.9%
Net margin – -3,535% 35.0%
FCF margin – -10,901% 30.2%
Operating cash flow margin – -10,840% 34.1%
Return on equity -157.0% -8.1% 22.2%
Return on assets -71.9% -7.5% 16.3%
Return on invested capital – – –
Return on capital employed -31.5% -11.4% 20.8%
Asset turnover – 0.0x 0.5x
Cash conversion (OCF / net income) – 2.0x 1.0x
Stock comp / revenue – 4,611% 5.5%

Financial Health

11 metrics
MetricNXTSROIVVRTX
Debt / assets 2.3% – –
Debt / equity 0.2x – –
Net debt / EBITDA 1.6x – –
Debt / FCF – – –
Liabilities / assets 89.8% 7.2% 26.2%
Equity / assets 10.2% 92.8% 73.8%
Interest coverage – – –
Current ratio 3.7x 16.7x 3.2x
Quick ratio 3.2x 13.5x 2.5x
Cash ratio 3.2x 13.5x 2.0x
Altman Z-score – 41.04 13.17

Shareholder Returns

7 metrics
MetricNXTSROIVVRTX
Dividend yield – – –
Net buyback yield – 0.0% 1.4%
Shareholder yield – 0.0% 1.4%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusNXTSROIVVRTX
Forward P/E – – 28.4xFY2026
EPS, next fiscal year – $-1.43FY2026 $18.22FY2026
EPS growth, next FY – – -1.0%FY2026
EPS growth, the year after – – +23.1%
Revenue, next fiscal year – $55.64MFY2026 $12.67BFY2026
Revenue growth, next FY – +573.6%FY2026 +5.8%FY2026
Revenue growth, the year after – +680.0% +18.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersNXTSROIVVRTX
Held by institutions – 77.0% 95.1%
Institutions holding – 498 1,745
Change in shares held, QoQ – +5.1% +3.9%
Institutions buying – 303 902
Institutions selling – 138 605
Buyers to sellers – 2.20 1.49

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

NXTSROIVVRTX
NXTS 1.00 0.02 0.06
ROIV 0.02 1.00 0.22
VRTX 0.06 0.22 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, NXTS, ROIV and VRTX?

Vertex Pharmaceuticals (VRTX) is the largest by market capitalisation: Nexentis Technologies (NXTS) $433.53K, Roivant Sciences (ROIV) $25.99B, Vertex Pharmaceuticals (VRTX) $130.22B.

Which company is growing faster?

Vertex Pharmaceuticals (VRTX) grew revenue fastest over the trailing twelve months: Roivant Sciences (ROIV) -67.6%, Vertex Pharmaceuticals (VRTX) +10.2%.

Which company is more profitable?

Vertex Pharmaceuticals (VRTX) has the highest net margin (Roivant Sciences (ROIV) -3,535.0%, Vertex Pharmaceuticals (VRTX) 35.0%).

Which stock has performed better?

Over the past year Roivant Sciences (ROIV) returned the most: Nexentis Technologies (NXTS) -97.9%, Roivant Sciences (ROIV) +97.9%, Vertex Pharmaceuticals (VRTX) +22.8%. Over five years, Roivant Sciences (ROIV) compounded fastest (Nexentis Technologies (NXTS) -86.1%/yr, Roivant Sciences (ROIV) +36.1%/yr, Vertex Pharmaceuticals (VRTX) +23.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Vertex Pharmaceuticals (VRTX) has been the steadiest (Nexentis Technologies (NXTS) 169.1%, Roivant Sciences (ROIV) 45.3%, Vertex Pharmaceuticals (VRTX) 29.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, NXTS, ROIV and VRTX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Vertex Pharmaceuticals (VRTX) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.