LLY vs PFE vs TAK Stock Comparison

Eli Lilly, Pfizer and Takeda Pharmaceutical Prices as of Oct 27, 2026 Peers: Industry group
LLY ELI LILLY & Co
$1,281.52 +8.2% 1M +55.1% 1Y
Market cap
$1.16T
P/E
43.3x
Revenue (TTM)
$79.67B
Div. yield
–
Pharmaceuticals Healthcare
8 wins
PFE Pfizer Inc
$29.80 +3.9% 1M +20.3% 1Y
Market cap
$167.64B
P/E
38.7x
Revenue (TTM)
$63.70B
Div. yield
0.06%
Pharmaceuticals Healthcare
2 wins

Head to Head

11 decided of 12

Eli Lilly leads on 8 of the 12 questions below (Eli Lilly 8, Pfizer 2, Takeda Pharmaceutical 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionLLYPFETAKLeader
Larger companyMarket capitalisation $1.16T $167.64B $63.46B LLY
Cheaper on earningsLower P/E, profitable companies only 43.3x 38.7x 110.5x PFE
Cheaper on forward earningsLower price / next fiscal year consensus EPS 39.6x 10.5x 50.7x PFE
Faster revenue growthRevenue growth, trailing twelve months +49.6% -0.2% +0.7% LLY
More profitableNet margin, trailing twelve months 33.5% 6.8% 1.2% LLY
Better return on capitalReturn on invested capital 37.2% 13.4% 3.5% LLY
Less leveragedLower net debt / EBITDA 1.1x 1.9x 3.5x LLY
Higher dividend yieldTrailing dividend yield 0.00% 0.06% 0.00% –
Better 1-year returnPrice return, last 12 months +55.1% +20.3% +43.2% LLY
Better 5-year returnAnnualised price return, 5 years +38.3%/yr -7.2%/yr +7.5%/yr LLY
Less volatileAnnualised volatility, 1 year 34.8% 21.6% 21.5% TAK
Higher overall scoreMean of the five percentile scores vs peers 72/100 65/100 62/100 LLY

Percentile Scorecard

LLYPFETAK

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisLLYPFETAK
Valuation 75 #156 of 625 95 #35 of 625 97 #17 of 625
Growth 98 #16 of 602 24 #461 of 602 21 #478 of 602
Profitability 98 #12 of 551 92 #45 of 551 85 #82 of 551
Financial Health 26 #484 of 656 24 #502 of 656 34 #431 of 656
Shareholder Returns 63 #137 of 365 91 #35 of 365 73 #98 of 365
Overall 72 65 62
  • LLY ranked among 672 companies in Pharmaceuticals and Biotechnology
  • PFE ranked among 672 companies in Pharmaceuticals and Biotechnology
  • TAK ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodLLYPFETAKSPY
1 month +8.2%+3.9%+7.6% -0.2%
3 months +4.8%+18.0%+15.6% +3.9%
6 months +46.6%+12.5%+23.6% +8.2%
Year to date +19.2%+19.7%+30.1% +12.9%
1 year +55.1%+20.3%+43.2% +12.3%
3 years +128.7%-1.0%+50.6% +87.4%
3 years, per year +31.8%-0.3%+14.6% +23.3%
5 years +405.8%-31.0%+43.8% +67.9%
5 years, per year +38.3%-7.2%+7.5% +10.9%
10 years +1,582.7%-8.3%-10.9% +261.1%
10 years, per year +32.6%-0.9%-1.2% +13.7%

Risk

MeasureLLYPFETAKSPY
Volatility, 1Y 34.8%21.6%21.5% 12.7%
Downside volatility, 1Y 29.9%21.1%20.2% 12.7%
Beta vs S&P 500, 1Y 0.230.230.11 1.00
Return / volatility, 1Y 1.580.942.01 0.97
Max drawdown, 5Y -34.8%-64.8%-26.4% -25.4%
From 52-week high -1.9%-2.0%-0.7% -1.2%
52-week high $1,306.74$30.41$20.43 $779.14
52-week low $813.53$23.67$13.23 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleLLYPFETAK
P/E now vs peer median 42.8xmedian 17.2x 39.2xmedian 17.2x 111.3xmedian 17.2x
P/S now vs peer median 15.1xmedian 9.0x 2.7xmedian 9.0x 1.4xmedian 9.0x
EV/EBITDA now vs peer median 31.1xmedian 16.3x 8.2xmedian 16.3x 12.4xmedian 16.3x
P/FCF now vs peer median 66.3xmedian 18.7x 15.5xmedian 18.7x 12.4xmedian 18.7x
P/B now vs peer median 35.6xmedian 2.2x 2.0xmedian 2.2x 1.4xmedian 2.2x
PEG now vs peer median 0.70median 0.33 -0.95median 0.33 -2.74median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsLLYPFETAK
Revenue $79.67B $63.70B $46.49B
Gross profit $66.44B $46.61B $30.58B
Operating income $38.18B $20.39B $2.71B
Net income $26.71B $4.36B -$1.04B
Free cash flow $18.19B $10.99B $5.20B
R&D $14.60B $11.05B $4.53B
EPS (diluted) $29.89 $0.76 $0.18
Cash & equivalents $8.95B $976.00M $2.85B
Total debt $54.91B $63.19B $126.30B
Shares (diluted) 893.70M 5.70B 3.15B
Enterprise value $1.12T $114.28B $39.82B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricLLYPFETAK
P/E 42.8x 39.2x 111.3x
P/FCF 66.3x 15.5x 12.4x
P/Operating cash flow 43.0x 12.7x 10.3x
P/S 15.1x 2.7x 1.4x
P/B 35.6x 2.0x 1.4x
P/Tangible book 76.5x 4.4x 2.5x
EV/EBITDA 31.1x 8.2x 12.4x
EV/EBIT 32.8x 10.9x 33.2x
EV/Revenue 15.7x 3.5x 1.9x
EV/FCF 68.8x 20.1x 17.3x
EV/Operating cash flow 44.6x 16.5x 14.3x
PEG (3Y EPS CAGR) 0.70 -0.95 -2.74

Growth

14 metrics
MetricLLYPFETAK
Revenue growth (1Y) 49.6% -0.2% 0.7%
Revenue CAGR (3Y) 39.2% -7.0% 14.8%
Gross profit growth (1Y) 51.0% 1.2% -0.8%
Gross profit CAGR (3Y) 42.5% -5.6% -0.2%
Operating income growth (1Y) 73.7% 1.5% -43.4%
Operating income CAGR (3Y) 71.0% -9.9% -14.3%
Net income growth (1Y) 93.6% -59.6% -209.1%
Net income CAGR (3Y) 60.2% -41.3% -35.3%
EPS growth (1Y) 94.9% -59.7% -75.7%
EPS CAGR (3Y) 60.7% -41.3% -40.6%
Operating cash flow growth (1Y) 156.7% -11.8% -14.8%
Operating cash flow CAGR (3Y) 65.1% -2.7% -4.4%
Free cash flow growth (1Y) 272.4% -11.7% -13.3%
Free cash flow CAGR (3Y) 69.8% 1.0% -5.2%

Profitability

14 metrics
MetricLLYPFETAK
Gross margin 83.4% 73.2% 65.8%
EBITDA margin 50.6% 42.4% 15.6%
Operating margin 47.9% 32.0% 5.8%
Pretax margin 42.2% 6.6% 2.6%
Net margin 33.5% 6.8% 1.2%
FCF margin 22.8% 17.2% 11.2%
Operating cash flow margin 35.3% 21.0% 13.5%
Return on equity 82.1% 5.0% 1.2%
Return on assets 20.6% 2.1% 0.6%
Return on invested capital 37.2% 13.4% 3.5%
Return on capital employed 46.7% 11.9% 3.0%
Asset turnover 0.6x 0.3x 0.5x
Cash conversion (OCF / net income) 1.1x 3.1x -6.0x
Stock comp / revenue 0.8% 1.5% 1.0%

Financial Health

11 metrics
MetricLLYPFETAK
Debt / assets 38.6% 31.4% 32.0%
Debt / equity 1.6x 0.7x 0.7x
Net debt / EBITDA 1.1x 1.9x 3.5x
Debt / FCF 3.0x 5.8x 6.0x
Liabilities / assets 76.2% 57.5% 51.7%
Equity / assets 23.8% 42.5% 48.3%
Interest coverage – – 0.8x
Current ratio 1.4x 1.3x 3.2x
Quick ratio 0.7x 0.7x 1.9x
Cash ratio 0.2x 0.4x 0.9x
Altman Z-score 8.58 2.36 1.57

Shareholder Returns

7 metrics
MetricLLYPFETAK
Dividend yield 0.5% 5.8% 1.5%
Net buyback yield 0.5% – 1.0%
Shareholder yield 1.0% 5.8% 2.5%
Payout ratio (earnings) – 224.5% –
Payout ratio (FCF) – 89.1% –
Dividend growth (1Y) – 1.5% –
Dividend CAGR (3Y) – 2.4% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusLLYPFETAK
Forward P/E 39.6xFY2026 10.5xFY2026 50.7xFY2026
EPS, next fiscal year $32.40FY2026 $2.85FY2026 $0.40FY2026
EPS growth, next FY +33.8%FY2026 -11.5%FY2026 +5.3%FY2026
EPS growth, the year after +42.2% -4.6% +62.5%
Revenue, next fiscal year $85.28BFY2026 $60.59BFY2026 $28.27BFY2026
Revenue growth, next FY +30.8%FY2026 -3.2%FY2026 -0.8%FY2026
Revenue growth, the year after +17.4% +3.9% +11.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersLLYPFETAK
Held by institutions 83.7% 66.9% 3.3%
Institutions holding 4,627 2,835 378
Change in shares held, QoQ +1.5% +2.0% +6.2%
Institutions buying 2,631 1,324 212
Institutions selling 1,469 1,204 98
Buyers to sellers 1.79 1.10 2.16

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

LLYPFETAK
LLY 1.00 0.43 0.38
PFE 0.43 1.00 0.43
TAK 0.38 0.43 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, LLY, PFE and TAK?

Eli Lilly (LLY) is the largest by market capitalisation: Eli Lilly (LLY) $1.16T, Pfizer (PFE) $167.64B, Takeda Pharmaceutical (TAK) $63.46B.

Which stock is cheaper, LLY, PFE and TAK?

Pfizer (PFE) trades on the lowest price-to-earnings ratio (Eli Lilly (LLY) 43.3x, Pfizer (PFE) 38.7x, Takeda Pharmaceutical (TAK) 110.5x). On next year's consensus earnings, Pfizer (PFE) is cheapest (Eli Lilly (LLY) 39.6x, Pfizer (PFE) 10.5x, Takeda Pharmaceutical (TAK) 50.7x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Eli Lilly (LLY) grew revenue fastest over the trailing twelve months: Eli Lilly (LLY) +49.6%, Pfizer (PFE) -0.2%, Takeda Pharmaceutical (TAK) +0.7%.

Which company is more profitable?

Eli Lilly (LLY) has the highest net margin (Eli Lilly (LLY) 33.5%, Pfizer (PFE) 6.8%, Takeda Pharmaceutical (TAK) 1.2%). On return on invested capital, Eli Lilly (LLY) leads (Eli Lilly (LLY) 37.2%, Pfizer (PFE) 13.4%, Takeda Pharmaceutical (TAK) 3.5%).

Which stock has performed better?

Over the past year Eli Lilly (LLY) returned the most: Eli Lilly (LLY) +55.1%, Pfizer (PFE) +20.3%, Takeda Pharmaceutical (TAK) +43.2%. Over five years, Eli Lilly (LLY) compounded fastest (Eli Lilly (LLY) +38.3%/yr, Pfizer (PFE) -7.2%/yr, Takeda Pharmaceutical (TAK) +7.5%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Eli Lilly (LLY) 0.00%, Pfizer (PFE) 0.06%, Takeda Pharmaceutical (TAK) 0.00%. Eli Lilly (LLY) and Takeda Pharmaceutical (TAK) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Takeda Pharmaceutical (TAK) has been the steadiest (Eli Lilly (LLY) 34.8%, Pfizer (PFE) 21.6%, Takeda Pharmaceutical (TAK) 21.5%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, LLY, PFE and TAK?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Eli Lilly (LLY) leads on 8. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.