ISRG vs MCK vs MDT Stock Comparison

Intuitive Surgical, Mckesson and Medtronic Prices as of Oct 23, 2026 Peers: Industry group
ISRG Intuitive Surgical Inc
$452.29 +13.6% 1M -18.0% 1Y
Market cap
$157.75B
P/E
53.3x
Revenue (TTM)
$11.58B
Div. yield
–
Medical Devices Healthcare
4 wins
MCK Mckesson Corp
$1,001.01 +13.6% 1M +26.2% 1Y
Market cap
$117.56B
P/E
25.6x
Revenue (TTM)
$410.98B
Div. yield
0.00%
Drug Distribution Healthcare
4 wins
MDT Medtronic plc
$95.41 +6.8% 1M +1.3% 1Y
Market cap
$121.22B
P/E
23.2x
Revenue (TTM)
$37.54B
Div. yield
0.03%
Medical Devices Healthcare
4 wins

Head to Head

12 decided of 12

Intuitive Surgical leads on 4 of the 12 questions below (Intuitive Surgical 4, Medtronic 4, Mckesson 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionISRGMCKMDTLeader
Larger companyMarket capitalisation $157.75B $117.56B $121.22B ISRG
Cheaper on earningsLower P/E, profitable companies only 53.3x 25.6x 23.2x MDT
Cheaper on forward earningsLower price / next fiscal year consensus EPS 40.9x 21.2x 17.1x MDT
Faster revenue growthRevenue growth, trailing twelve months +20.5% +8.8% +9.8% ISRG
More profitableNet margin, trailing twelve months 25.5% 1.1% 13.9% ISRG
Better return on capitalReturn on invested capital — 107.9% 6.9% MCK
Less leveragedLower net debt / EBITDA — 0.6x 2.0x MCK
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.03% MDT
Better 1-year returnPrice return, last 12 months -18.0% +26.2% +1.3% MCK
Better 5-year returnAnnualised price return, 5 years +5.8%/yr +36.8%/yr -5.0%/yr MCK
Less volatileAnnualised volatility, 1 year 34.6% 30.6% 24.7% MDT
Higher overall scoreMean of the five percentile scores vs peers 80/100 60/100 66/100 ISRG

Percentile Scorecard

ISRGMCKMDT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisISRGMCKMDT
Valuation 52 #110 of 228 54 #12 of 25 85 #36 of 228
Growth 80 #46 of 222 65 #9 of 24 50 #111 of 222
Profitability 98 #6 of 210 65 #9 of 24 88 #26 of 210
Financial Health 78 #53 of 241 52 #13 of 26 50 #122 of 241
Shareholder Returns 92 #12 of 138 63 #7 of 17 56 #62 of 138
Overall 80 60 66
  • ISRG ranked among 248 companies in Medical Devices and Diagnostics
  • MCK ranked among 27 companies in Healthcare Payers and Distributors
  • MDT ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodISRGMCKMDTSPY
1 month +13.6%+13.6%+6.8% -1.0%
3 months +34.0%+19.1%+14.7% +2.9%
6 months -6.2%+20.9%+14.5% +6.4%
Year to date -20.1%+22.0%-0.7% +11.4%
1 year -18.0%+26.2%+1.3% +13.1%
3 years +63.1%+121.4%+32.6% +79.4%
3 years, per year +17.7%+30.4%+9.9% +21.5%
5 years +32.4%+378.7%-22.5% +67.7%
5 years, per year +5.8%+36.8%-5.0% +10.9%
10 years +500.3%+521.6%+13.7% +255.2%
10 years, per year +19.6%+20.1%+1.3% +13.5%

Risk

MeasureISRGMCKMDTSPY
Volatility, 1Y 34.6%30.6%24.7% 12.7%
Downside volatility, 1Y 37.5%27.4%22.0% 12.7%
Beta vs S&P 500, 1Y 0.89-0.250.11 1.00
Return / volatility, 1Y -0.520.860.05 1.03
Max drawdown, 5Y -49.9%-27.2%-44.0% -25.4%
From 52-week high -23.7%-2.8%-9.4% -2.5%
52-week high $592.85$1,030.18$105.35 $779.14
52-week low $332.02$725.17$73.75 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleISRGMCKMDT
P/E now vs peer median 53.4xmedian 30.7x 25.9xmedian 24.5x 23.3xmedian 30.7x
P/S now vs peer median 13.5xmedian 3.0x 0.3xmedian 0.3x 3.3xmedian 3.0x
EV/EBITDA now vs peer median 37.3xmedian 17.7x 16.7xmedian 14.4x 14.5xmedian 17.7x
P/FCF now vs peer median 43.6xmedian 23.7x 18.2xmedian 15.8x 19.9xmedian 23.7x
P/B now vs peer median 9.7xmedian 2.4x -27.5xmedian 2.5x 2.4xmedian 2.4x
PEG now vs peer median 2.08median 0.96 2.16median 1.35 1.61median 0.96

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsISRGMCKMDT
Revenue $11.58B $410.98B $37.54B
Gross profit $7.78B $14.96B $24.41B
Operating income $3.28B $6.50B $6.79B
Net income $2.97B $5.30B $5.27B
Free cash flow $3.60B $6.42B $6.13B
R&D $1.49B – $2.92B
EPS (diluted) $8.41 $38.52 $4.07
Cash & equivalents $2.98B $5.16B $1.69B
Total debt – $9.73B $113.29B
Shares (diluted) 351.60M 119.20M 1.29B
Enterprise value $138.04B $101.45B $86.47B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricISRGMCKMDT
P/E 53.4x 25.9x 23.3x
P/FCF 43.6x 18.2x 19.9x
P/Operating cash flow 38.3x 17.0x 15.2x
P/S 13.5x 0.3x 3.3x
P/B 9.7x -27.5x 2.4x
P/Tangible book 10.5x -14.1x 3.0x
EV/EBITDA 37.3x 16.7x 14.5x
EV/EBIT 46.5x 18.7x 20.8x
EV/Revenue 13.2x 0.3x 3.8x
EV/FCF 42.4x 18.9x 23.1x
EV/Operating cash flow 37.3x 17.7x 17.6x
PEG (3Y EPS CAGR) 2.08 2.16 1.61

Growth

14 metrics
MetricISRGMCKMDT
Revenue growth (1Y) 20.5% 8.8% 9.8%
Revenue CAGR (3Y) 19.1% 13.1% 6.0%
Gross profit growth (1Y) 21.9% 11.2% 9.3%
Gross profit CAGR (3Y) 19.5% 6.6% 5.6%
Operating income growth (1Y) 16.6% 46.6% 10.9%
Operating income CAGR (3Y) 24.8% 13.5% 6.4%
Net income growth (1Y) 7.5% 58.1% 12.4%
Net income CAGR (3Y) 24.4% 10.7% 13.0%
EPS growth (1Y) 10.8% 52.8% 12.4%
EPS CAGR (3Y) 25.7% 12.0% 14.5%
Operating cash flow growth (1Y) 38.1% 4.7% 12.4%
Operating cash flow CAGR (3Y) 26.4% 10.7% 11.3%
Free cash flow growth (1Y) 58.4% 6.8% 15.6%
Free cash flow CAGR (3Y) 42.0% 11.3% 11.3%

Profitability

14 metrics
MetricISRGMCKMDT
Gross margin 67.2% 3.6% 65.0%
EBITDA margin 35.3% 1.8% 25.9%
Operating margin 28.4% 1.6% 18.1%
Pretax margin 31.3% 1.6% 17.6%
Net margin 25.5% 1.1% 13.9%
FCF margin 31.1% 1.6% 16.3%
Operating cash flow margin 35.3% 1.7% 21.4%
Return on equity 17.3% – 10.4%
Return on assets 14.8% 6.2% 5.7%
Return on invested capital – 107.9% 6.9%
Return on capital employed 18.7% 43.4% 8.3%
Asset turnover 0.6x 4.8x 0.4x
Cash conversion (OCF / net income) 1.4x 1.3x 1.5x
Stock comp / revenue 7.2% – 1.3%

Financial Health

11 metrics
MetricISRGMCKMDT
Debt / assets – 11.0% 30.2%
Debt / equity – -2.3x 0.6x
Net debt / EBITDA – 0.6x 2.0x
Debt / FCF – 1.5x 4.6x
Liabilities / assets 16.7% 104.8% 45.5%
Equity / assets 83.3% -4.8% 54.5%
Interest coverage – 23.6x 9.4x
Current ratio 3.3x 0.9x 2.1x
Quick ratio 2.3x 0.5x 1.3x
Cash ratio 1.6x 0.1x 0.7x
Altman Z-score 30.96 5.91 3.03

Shareholder Returns

7 metrics
MetricISRGMCKMDT
Dividend yield – 0.3% 3.0%
Net buyback yield 2.7% 5.7% 0.2%
Shareholder yield 2.7% 6.0% 3.2%
Payout ratio (earnings) – 7.4% 69.3%
Payout ratio (FCF) – 6.1% 59.5%
Dividend growth (1Y) – 11.3% 1.4%
Dividend CAGR (3Y) – 10.0% 0.2%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusISRGMCKMDT
Forward P/E 40.9xFY2026 21.2xFY2026 17.1xFY2026
EPS, next fiscal year $11.05FY2026 $47.14FY2026 $5.57FY2026
EPS growth, next FY +23.7%FY2026 +20.5%FY2026 +0.7%FY2026
EPS growth, the year after +5.5% +11.1% +7.4%
Revenue, next fiscal year $11.45BFY2026 $444.51BFY2026 $39.92BFY2026
Revenue growth, next FY +13.9%FY2026 +10.2%FY2026 +9.8%FY2026
Revenue growth, the year after +12.2% +1.4% -4.7%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersISRGMCKMDT
Held by institutions 86.2% 89.1% 85.1%
Institutions holding 2,235 2,007 2,124
Change in shares held, QoQ +4.6% -0.7% -0.2%
Institutions buying 1,070 879 1,013
Institutions selling 877 791 913
Buyers to sellers 1.22 1.11 1.11

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ISRGMCKMDT
ISRG 1.00 0.11 0.44
MCK 0.11 1.00 0.30
MDT 0.44 0.30 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ISRG, MCK and MDT?

Intuitive Surgical (ISRG) is the largest by market capitalisation: Intuitive Surgical (ISRG) $157.75B, Mckesson (MCK) $117.56B, Medtronic (MDT) $121.22B.

Which stock is cheaper, ISRG, MCK and MDT?

Medtronic (MDT) trades on the lowest price-to-earnings ratio (Intuitive Surgical (ISRG) 53.3x, Mckesson (MCK) 25.6x, Medtronic (MDT) 23.2x). On next year's consensus earnings, Medtronic (MDT) is cheapest (Intuitive Surgical (ISRG) 40.9x, Mckesson (MCK) 21.2x, Medtronic (MDT) 17.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Intuitive Surgical (ISRG) grew revenue fastest over the trailing twelve months: Intuitive Surgical (ISRG) +20.5%, Mckesson (MCK) +8.8%, Medtronic (MDT) +9.8%.

Which company is more profitable?

Intuitive Surgical (ISRG) has the highest net margin (Intuitive Surgical (ISRG) 25.5%, Mckesson (MCK) 1.1%, Medtronic (MDT) 13.9%). On return on invested capital, Mckesson (MCK) leads (Mckesson (MCK) 107.9%, Medtronic (MDT) 6.9%).

Which stock has performed better?

Over the past year Mckesson (MCK) returned the most: Intuitive Surgical (ISRG) -18.0%, Mckesson (MCK) +26.2%, Medtronic (MDT) +1.3%. Over five years, Mckesson (MCK) compounded fastest (Intuitive Surgical (ISRG) +5.8%/yr, Mckesson (MCK) +36.8%/yr, Medtronic (MDT) -5.0%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Medtronic (MDT) has the highest dividend yield: Intuitive Surgical (ISRG) 0.00%, Mckesson (MCK) 0.00%, Medtronic (MDT) 0.03%. Intuitive Surgical (ISRG) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Medtronic (MDT) has been the steadiest (Intuitive Surgical (ISRG) 34.6%, Mckesson (MCK) 30.6%, Medtronic (MDT) 24.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ISRG, MCK and MDT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Intuitive Surgical (ISRG) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.