BIO vs ILMN vs TMO Stock Comparison

Bio-Rad Laboratories, Illumina and Thermo Fisher Scientific Prices as of Oct 23, 2026 Peers: Industry group
ILMN Illumina, Inc.
$269.42 +5.5% 1M +169.5% 1Y
Market cap
$40.91B
P/E
49.6x
Revenue (TTM)
$4.49B
Div. yield
–
Life Sciences Tools Healthcare
5 wins

Head to Head

11 decided of 12

Thermo Fisher Scientific leads on 6 of the 12 questions below (Thermo Fisher Scientific 6, Illumina 5). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBIOILMNTMOLeader
Larger companyMarket capitalisation $9.97B $40.91B $254.18B TMO
Cheaper on earningsLower P/E, profitable companies only 44.8x 49.6x 36.5x TMO
Cheaper on forward earningsLower price / next fiscal year consensus EPS 37.2x 53.9x 26.1x TMO
Faster revenue growthRevenue growth, trailing twelve months +1.4% +4.9% +7.2% TMO
More profitableNet margin, trailing twelve months 8.6% 18.4% 15.0% ILMN
Better return on capitalReturn on invested capital 0.4% 15.1% 7.9% ILMN
Less leveragedLower net debt / EBITDA — 0.7x 3.5x ILMN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +9.3% +169.5% +17.8% ILMN
Better 5-year returnAnnualised price return, 5 years -13.3%/yr -7.5%/yr +1.9%/yr TMO
Less volatileAnnualised volatility, 1 year 37.0% 50.3% 29.8% TMO
Higher overall scoreMean of the five percentile scores vs peers 64/100 65/100 59/100 ILMN

Percentile Scorecard

BIOILMNTMO

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBIOILMNTMO
Valuation 79 #49 of 228 52 #111 of 228 60 #93 of 228
Growth 19 #180 of 222 43 #126 of 222 35 #144 of 222
Profitability 69 #65 of 210 97 #7 of 210 83 #37 of 210
Financial Health 69 #75 of 241 51 #118 of 241 28 #174 of 241
Shareholder Returns 83 #24 of 138 84 #23 of 138 88 #18 of 138
Overall 64 65 59
  • BIO ranked among 248 companies in Medical Devices and Diagnostics
  • ILMN ranked among 248 companies in Medical Devices and Diagnostics
  • TMO ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBIOILMNTMOSPY
1 month -2.3%+5.5%+1.2% -1.0%
3 months +17.6%+38.8%+18.6% +2.9%
6 months +28.6%+110.7%+43.5% +6.4%
Year to date +22.2%+105.4%+16.3% +11.4%
1 year +9.3%+169.5%+17.8% +13.1%
3 years +21.9%+138.6%+47.1% +79.4%
3 years, per year +6.8%+33.6%+13.7% +21.5%
5 years -50.9%-32.3%+10.1% +67.7%
5 years, per year -13.3%-7.5%+1.9% +10.9%
10 years +127.0%+95.3%+347.3% +255.2%
10 years, per year +8.5%+6.9%+16.2% +13.5%

Risk

MeasureBIOILMNTMOSPY
Volatility, 1Y 37.0%50.3%29.8% 12.7%
Downside volatility, 1Y 35.7%39.1%28.3% 12.7%
Beta vs S&P 500, 1Y 0.740.800.59 1.00
Return / volatility, 1Y 0.253.370.60 1.03
Max drawdown, 5Y -72.7%-82.9%-41.5% -25.4%
From 52-week high -5.2%-8.3%-3.3% -2.5%
52-week high $390.34$293.69$696.55 $779.14
52-week low $241.71$95.03$438.34 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBIOILMNTMO
P/E now vs peer median 44.5xmedian 30.7x 49.3xmedian 30.7x 35.9xmedian 30.7x
P/S now vs peer median 3.8xmedian 3.0x 9.1xmedian 3.0x 5.4xmedian 3.0x
EV/EBITDA now vs peer median —median 17.7x 36.0xmedian 17.7x 25.9xmedian 17.7x
P/FCF now vs peer median 28.0xmedian 23.7x 43.7xmedian 23.7x 34.0xmedian 23.7x
P/B now vs peer median 1.4xmedian 2.4x 14.3xmedian 2.4x 4.7xmedian 2.4x
PEG now vs peer median 1.20median 0.96 1.64median 0.96 4.27median 0.96

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBIOILMNTMO
Revenue $2.59B $4.49B $46.34B
Gross profit $1.34B $2.98B $18.91B
Operating income $53.10M $882.00M $8.15B
Net income $222.40M $825.00M $6.99B
Free cash flow $353.10M $931.00M $7.32B
R&D $265.70M $960.00M $1.40B
EPS (diluted) $8.29 $5.39 $18.78
Cash & equivalents $517.00M $1.04B $4.06B
Total debt $1.20B $6.97B $42.55B
Shares (diluted) 26.81M 153.00M 371.00M
Enterprise value $3.83B $35.68B $233.20B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBIOILMNTMO
P/E 44.5x 49.3x 35.9x
P/FCF 28.0x 43.7x 34.0x
P/Operating cash flow 20.1x 37.2x 27.6x
P/S 3.8x 9.1x 5.4x
P/B 1.4x 14.3x 4.7x
P/Tangible book 1.4x 16.8x 7.3x
EV/EBITDA – 36.0x 25.9x
EV/EBIT 178.6x 47.1x 35.3x
EV/Revenue 3.7x 9.2x 6.2x
EV/FCF 26.9x 44.6x 39.3x
EV/Operating cash flow 19.2x 37.9x 31.9x
PEG (3Y EPS CAGR) 1.20 1.64 4.27

Growth

14 metrics
MetricBIOILMNTMO
Revenue growth (1Y) 1.4% 4.9% 7.2%
Revenue CAGR (3Y) -2.2% -1.0% 2.1%
Gross profit growth (1Y) -0.4% 4.6% 6.2%
Gross profit CAGR (3Y) -3.5% 2.9% 3.0%
Operating income growth (1Y) -76.3% -31.8% 10.0%
Operating income CAGR (3Y) -47.4% 28.3% 6.7%
Net income growth (1Y) -30.3% -34.4% 6.2%
Net income CAGR (3Y) 36.1% 30.0% 6.9%
EPS growth (1Y) -29.3% -32.7% 7.8%
EPS CAGR (3Y) 36.9% 30.1% 8.4%
Operating cash flow growth (1Y) -7.8% -5.1% 18.9%
Operating cash flow CAGR (3Y) 19.8% 38.1% 5.4%
Free cash flow growth (1Y) -4.8% -9.7% 18.6%
Free cash flow CAGR (3Y) 31.9% 105.0% 7.7%

Profitability

14 metrics
MetricBIOILMNTMO
Gross margin 51.9% 66.4% 40.8%
EBITDA margin – 25.7% 23.9%
Operating margin 2.1% 19.6% 17.6%
Pretax margin 13.5% 22.6% 16.5%
Net margin 8.6% 18.4% 15.0%
FCF margin 13.6% 20.7% 15.8%
Operating cash flow margin 19.0% 24.4% 19.5%
Return on equity 3.2% 29.9% 13.4%
Return on assets 2.2% 12.5% 6.2%
Return on invested capital 0.4% 15.1% 7.9%
Return on capital employed 0.6% 17.5% 8.3%
Asset turnover 0.3x 0.7x 0.4x
Cash conversion (OCF / net income) 2.2x 1.3x 1.3x
Stock comp / revenue – 5.9% 0.7%

Financial Health

11 metrics
MetricBIOILMNTMO
Debt / assets 11.7% 29.9% 37.6%
Debt / equity 0.2x 0.7x 0.8x
Net debt / EBITDA – 0.7x 3.5x
Debt / FCF 3.4x 2.1x 5.8x
Liabilities / assets 30.0% 57.3% 53.4%
Equity / assets 70.0% 42.7% 46.6%
Interest coverage 1.1x 8.9x 5.6x
Current ratio 3.1x 1.8x 1.6x
Quick ratio 2.1x 1.2x 1.0x
Cash ratio 1.7x 0.7x 0.3x
Altman Z-score 3.54 7.73 3.98

Shareholder Returns

7 metrics
MetricBIOILMNTMO
Dividend yield – – 0.3%
Net buyback yield 1.2% 1.2% 2.0%
Shareholder yield 1.2% 1.2% 2.3%
Payout ratio (earnings) – – 9.5%
Payout ratio (FCF) – – 9.0%
Dividend growth (1Y) – – 8.5%
Dividend CAGR (3Y) – – 10.8%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBIOILMNTMO
Forward P/E 37.2xFY2026 53.9xFY2026 26.1xFY2026
EPS, next fiscal year $9.95FY2026 $5.00FY2026 $25.77FY2026
EPS growth, next FY +0.3%FY2026 +3.3%FY2026 +12.7%FY2026
EPS growth, the year after -0.3% +25.4% +1.8%
Revenue, next fiscal year $2.69BFY2026 $4.52BFY2026 $49.99BFY2026
Revenue growth, next FY +4.2%FY2026 +4.1%FY2026 +12.2%FY2026
Revenue growth, the year after -6.3% +12.0% -2.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBIOILMNTMO
Held by institutions 89.5% 100.0% 90.2%
Institutions holding 403 933 2,621
Change in shares held, QoQ -2.9% +0.0% +0.8%
Institutions buying 177 463 1,141
Institutions selling 155 330 1,144
Buyers to sellers 1.14 1.40 1.00

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BIOILMNTMO
BIO 1.00 0.34 0.57
ILMN 0.34 1.00 0.50
TMO 0.57 0.50 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, BIO, ILMN and TMO?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: Bio-Rad Laboratories (BIO) $9.97B, Illumina (ILMN) $40.91B, Thermo Fisher Scientific (TMO) $254.18B.

Which stock is cheaper, BIO, ILMN and TMO?

Thermo Fisher Scientific (TMO) trades on the lowest price-to-earnings ratio (Bio-Rad Laboratories (BIO) 44.8x, Illumina (ILMN) 49.6x, Thermo Fisher Scientific (TMO) 36.5x). On next year's consensus earnings, Thermo Fisher Scientific (TMO) is cheapest (Bio-Rad Laboratories (BIO) 37.2x, Illumina (ILMN) 53.9x, Thermo Fisher Scientific (TMO) 26.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Thermo Fisher Scientific (TMO) grew revenue fastest over the trailing twelve months: Bio-Rad Laboratories (BIO) +1.4%, Illumina (ILMN) +4.9%, Thermo Fisher Scientific (TMO) +7.2%.

Which company is more profitable?

Illumina (ILMN) has the highest net margin (Bio-Rad Laboratories (BIO) 8.6%, Illumina (ILMN) 18.4%, Thermo Fisher Scientific (TMO) 15.0%). On return on invested capital, Illumina (ILMN) leads (Bio-Rad Laboratories (BIO) 0.4%, Illumina (ILMN) 15.1%, Thermo Fisher Scientific (TMO) 7.9%).

Which stock has performed better?

Over the past year Illumina (ILMN) returned the most: Bio-Rad Laboratories (BIO) +9.3%, Illumina (ILMN) +169.5%, Thermo Fisher Scientific (TMO) +17.8%. Over five years, Thermo Fisher Scientific (TMO) compounded fastest (Bio-Rad Laboratories (BIO) -13.3%/yr, Illumina (ILMN) -7.5%/yr, Thermo Fisher Scientific (TMO) +1.9%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Bio-Rad Laboratories (BIO) 0.00%, Illumina (ILMN) 0.00%, Thermo Fisher Scientific (TMO) 0.00%. Bio-Rad Laboratories (BIO) and Illumina (ILMN) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Thermo Fisher Scientific (TMO) has been the steadiest (Bio-Rad Laboratories (BIO) 37.0%, Illumina (ILMN) 50.3%, Thermo Fisher Scientific (TMO) 29.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BIO, ILMN and TMO?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Thermo Fisher Scientific (TMO) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.