BIIB vs MRNA vs REGN Stock Comparison

Biogen, Moderna and Regeneron Pharmaceuticals Prices as of Oct 27, 2026 Peers: Industry group
BIIB Biogen Inc.
$252.73 +11.0% 1M +68.0% 1Y
Market cap
$37.36B
P/E
44.8x
Revenue (TTM)
$10.03B
Div. yield
–
Biotechnology Healthcare
MRNA Moderna, Inc.
$207.97 +4.6% 1M +680.1% 1Y
Market cap
$86.49B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
2 wins

Head to Head

11 decided of 12

Regeneron Pharmaceuticals leads on 9 of the 12 questions below (Regeneron Pharmaceuticals 9, Moderna 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBIIBMRNAREGNLeader
Larger companyMarket capitalisation $37.36B $86.49B $84.26B MRNA
Cheaper on earningsLower P/E, profitable companies only 44.8x -27.4x 19.5x REGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 19.7x — 14.3x REGN
Faster revenue growthRevenue growth, trailing twelve months +0.3% -27.6% +9.3% REGN
More profitableNet margin, trailing twelve months 8.3% -141.4% 27.9% REGN
Better return on capitalReturn on invested capital 3.3% -43.3% 9.6% REGN
Less leveragedLower net debt / EBITDA 3.2x 1.5x -1.4x REGN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +68.0% +680.1% +39.4% MRNA
Better 5-year returnAnnualised price return, 5 years -0.9%/yr -9.8%/yr +5.5%/yr REGN
Less volatileAnnualised volatility, 1 year 34.0% 130.8% 32.8% REGN
Higher overall scoreMean of the five percentile scores vs peers 63/100 57/100 72/100 REGN

Percentile Scorecard

BIIBMRNAREGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBIIBMRNAREGN
Valuation 92 #52 of 625 69 #193 of 625 89 #71 of 625
Growth 35 #392 of 602 18 #493 of 602 42 #351 of 602
Profitability 89 #64 of 551 57 #239 of 551 90 #54 of 551
Financial Health 35 #425 of 656 55 #298 of 656 74 #172 of 656
Shareholder Returns – 85 #57 of 365 65 #129 of 365
Overall 63 57 72
  • BIIB ranked among 672 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • REGN ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBIIBMRNAREGNSPY
1 month +11.0%+4.6%+3.6% -0.2%
3 months +22.9%+272.6%+17.4% +3.9%
6 months +37.8%+341.2%+11.5% +8.2%
Year to date +43.6%+605.2%+5.7% +12.9%
1 year +68.0%+680.1%+39.4% +12.3%
3 years +7.8%+189.2%+5.3% +87.4%
3 years, per year +2.5%+42.5%+1.7% +23.3%
5 years -4.6%-40.2%+30.5% +67.9%
5 years, per year -0.9%-9.8%+5.5% +10.9%
10 years -13.1%—+123.4% +261.1%
10 years, per year -1.4%—+8.4% +13.7%

Risk

MeasureBIIBMRNAREGNSPY
Volatility, 1Y 34.0%130.8%32.8% 12.7%
Downside volatility, 1Y 32.3%79.5%30.0% 12.7%
Beta vs S&P 500, 1Y 0.262.150.47 1.00
Return / volatility, 1Y 2.005.201.20 0.97
Max drawdown, 5Y -64.4%-93.9%-59.8% -25.4%
From 52-week high -0.4%-15.4%-4.2% -1.2%
52-week high $253.84$245.81$852.03 $779.14
52-week low $147.86$22.36$585.31 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBIIBMRNAREGN
P/E now vs peer median 44.7xmedian 17.2x -26.3xmedian 17.2x 19.4xmedian 17.2x
P/S now vs peer median 3.7xmedian 9.0x 37.2xmedian 9.0x 5.4xmedian 9.0x
EV/EBITDA now vs peer median 23.4xmedian 16.3x -25.5xmedian 16.3x 17.8xmedian 16.3x
P/FCF now vs peer median 13.8xmedian 18.7x -66.7xmedian 18.7x 22.3xmedian 18.7x
P/B now vs peer median 2.0xmedian 2.2x 12.3xmedian 2.2x 2.6xmedian 2.2x
PEG now vs peer median -1.37median 0.33 0.40median 0.33 7.29median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBIIBMRNAREGN
Revenue $10.03B $2.23B $15.53B
Gross profit $7.42B $521.00M $13.18B
Operating income $1.01B -$3.32B $3.84B
Net income $834.60M -$3.15B $4.33B
Free cash flow $2.70B -$1.24B $3.76B
R&D $2.01B $2.88B $6.28B
EPS (diluted) $5.61 $-7.92 $40.84
Cash & equivalents $1.29B $1.72B $2.46B
Total debt $7.29B $591.00M $1.99B
Shares (diluted) 148.70M 398.00M 106.00M
Enterprise value $24.02B $65.84B $50.47B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBIIBMRNAREGN
P/E 44.7x -26.3x 19.4x
P/FCF 13.8x -66.7x 22.3x
P/Operating cash flow 13.0x -77.3x 17.9x
P/S 3.7x 37.2x 5.4x
P/B 2.0x 12.3x 2.6x
P/Tangible book 7.0x 12.3x 2.8x
EV/EBITDA 23.4x -25.5x 17.8x
EV/EBIT 42.9x -23.6x 20.3x
EV/Revenue 4.3x 35.2x 5.0x
EV/FCF 16.1x -63.0x 20.7x
EV/Operating cash flow 15.1x -73.1x 16.6x
PEG (3Y EPS CAGR) -1.37 0.40 7.29

Growth

14 metrics
MetricBIIBMRNAREGN
Revenue growth (1Y) 0.3% -27.6% 9.3%
Revenue CAGR (3Y) 0.2% -40.6% 7.0%
Gross profit growth (1Y) -1.6% -67.8% 8.4%
Gross profit CAGR (3Y) -1.1% -56.0% 6.4%
Operating income growth (1Y) -43.7% -1.4% 0.1%
Operating income CAGR (3Y) -31.3% -103.9% -3.9%
Net income growth (1Y) -45.5% -8.5% -2.9%
Net income CAGR (3Y) -32.1% -66.4% 0.2%
EPS growth (1Y) -46.2% -5.8% -0.5%
EPS CAGR (3Y) -32.6% -65.1% 2.7%
Operating cash flow growth (1Y) 36.0% 60.2% -1.3%
Operating cash flow CAGR (3Y) 26.3% -68.1% -0.4%
Free cash flow growth (1Y) 36.3% 64.4% -2.4%
Free cash flow CAGR (3Y) 33.0% -18.2% -3.3%

Profitability

14 metrics
MetricBIIBMRNAREGN
Gross margin 74.0% 23.4% 84.9%
EBITDA margin 18.5% -138.2% 28.1%
Operating margin 10.1% -149.0% 24.7%
Pretax margin 10.1% -138.6% 33.3%
Net margin 8.3% -141.4% 27.9%
FCF margin 26.9% -55.8% 24.2%
Operating cash flow margin 28.7% -48.2% 30.1%
Return on equity 4.5% -44.5% 13.7%
Return on assets 2.7% -28.1% 10.5%
Return on invested capital 3.3% -43.3% 9.6%
Return on capital employed 3.8% -38.2% 10.7%
Asset turnover 0.3x 0.2x 0.4x
Cash conversion (OCF / net income) 3.4x 0.3x 1.1x
Stock comp / revenue 3.0% 20.7% 6.4%

Financial Health

11 metrics
MetricBIIBMRNAREGN
Debt / assets 22.7% 5.4% 4.8%
Debt / equity 0.4x 0.1x 0.1x
Net debt / EBITDA 3.2x 1.5x -1.4x
Debt / FCF 2.7x -0.5x 0.5x
Liabilities / assets 41.3% 38.3% 24.0%
Equity / assets 58.7% 61.7% 76.0%
Interest coverage – – 69.4x
Current ratio 1.9x 2.3x 3.3x
Quick ratio 1.1x 2.0x 2.6x
Cash ratio 0.3x 2.0x 1.4x
Altman Z-score 3.15 12.07 7.33

Shareholder Returns

7 metrics
MetricBIIBMRNAREGN
Dividend yield – – 0.5%
Net buyback yield – -0.1% 3.0%
Shareholder yield – -0.1% 3.5%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBIIBMRNAREGN
Forward P/E 19.7xFY2026 – 14.3xFY2026
EPS, next fiscal year $12.81FY2026 $-8.02FY2026 $57.08FY2026
EPS growth, next FY -16.2%FY2026 – +28.8%FY2026
EPS growth, the year after +36.5% – +15.5%
Revenue, next fiscal year $9.96BFY2026 $2.04BFY2026 $17.05BFY2026
Revenue growth, next FY +0.7%FY2026 +5.1%FY2026 +18.9%FY2026
Revenue growth, the year after +11.9% +26.8% +13.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBIIBMRNAREGN
Held by institutions 96.4% 80.2% 66.2%
Institutions holding 1,036 784 1,325
Change in shares held, QoQ +6.0% +3.4% +3.8%
Institutions buying 548 402 604
Institutions selling 294 238 534
Buyers to sellers 1.86 1.69 1.13

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BIIBMRNAREGN
BIIB 1.00 0.23 0.36
MRNA 0.23 1.00 0.26
REGN 0.36 0.26 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, BIIB, MRNA and REGN?

Moderna (MRNA) is the largest by market capitalisation: Biogen (BIIB) $37.36B, Moderna (MRNA) $86.49B, Regeneron Pharmaceuticals (REGN) $84.26B.

Which stock is cheaper, BIIB, MRNA and REGN?

Regeneron Pharmaceuticals (REGN) trades on the lowest price-to-earnings ratio (Biogen (BIIB) 44.8x, Moderna (MRNA) -27.4x, Regeneron Pharmaceuticals (REGN) 19.5x). On next year's consensus earnings, Regeneron Pharmaceuticals (REGN) is cheapest (Biogen (BIIB) 19.7x, Regeneron Pharmaceuticals (REGN) 14.3x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Regeneron Pharmaceuticals (REGN) grew revenue fastest over the trailing twelve months: Biogen (BIIB) +0.3%, Moderna (MRNA) -27.6%, Regeneron Pharmaceuticals (REGN) +9.3%.

Which company is more profitable?

Regeneron Pharmaceuticals (REGN) has the highest net margin (Biogen (BIIB) 8.3%, Moderna (MRNA) -141.4%, Regeneron Pharmaceuticals (REGN) 27.9%). On return on invested capital, Regeneron Pharmaceuticals (REGN) leads (Biogen (BIIB) 3.3%, Moderna (MRNA) -43.3%, Regeneron Pharmaceuticals (REGN) 9.6%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: Biogen (BIIB) +68.0%, Moderna (MRNA) +680.1%, Regeneron Pharmaceuticals (REGN) +39.4%. Over five years, Regeneron Pharmaceuticals (REGN) compounded fastest (Biogen (BIIB) -0.9%/yr, Moderna (MRNA) -9.8%/yr, Regeneron Pharmaceuticals (REGN) +5.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Regeneron Pharmaceuticals (REGN) has been the steadiest (Biogen (BIIB) 34.0%, Moderna (MRNA) 130.8%, Regeneron Pharmaceuticals (REGN) 32.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BIIB, MRNA and REGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Regeneron Pharmaceuticals (REGN) leads on 9. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.