ARGX vs BIIB vs BNTX Stock Comparison

Argenx Se, Biogen and BioNTech SE Prices as of Oct 27, 2026 Peers: Industry group
ARGX Argenx Se
$882.48 -8.0% 1M +6.3% 1Y
Market cap
$54.33B
P/E
28.9x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
6 wins
BIIB Biogen Inc.
$252.73 +11.0% 1M +68.0% 1Y
Market cap
$36.02B
P/E
43.2x
Revenue (TTM)
$10.03B
Div. yield
–
Biotechnology Healthcare
5 wins
BNTX BioNTech SE
$87.06 -11.6% 1M -17.9% 1Y
Market cap
$21.05B
P/E
–
Revenue (TTM)
$3.09B
Div. yield
–
Biotechnology Healthcare

Head to Head

11 decided of 12

Argenx Se leads on 6 of the 12 questions below (Argenx Se 6, Biogen 5). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionARGXBIIBBNTXLeader
Larger companyMarket capitalisation $54.33B $36.02B $21.05B ARGX
Cheaper on earningsLower P/E, profitable companies only 28.9x 43.2x -10.7x ARGX
Cheaper on forward earningsLower price / next fiscal year consensus EPS 28.8x 19.7x — BIIB
Faster revenue growthRevenue growth, trailing twelve months +61.5% +0.3% -1.1% ARGX
More profitableNet margin, trailing twelve months 32.3% 8.3% -63.5% ARGX
Better return on capitalReturn on invested capital — 3.3% -10.7% BIIB
Less leveragedLower net debt / EBITDA — 3.2x 8.7x BIIB
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +6.3% +68.0% -17.9% BIIB
Better 5-year returnAnnualised price return, 5 years +25.8%/yr -0.9%/yr -21.1%/yr ARGX
Less volatileAnnualised volatility, 1 year 36.9% 34.0% 46.6% BIIB
Higher overall scoreMean of the five percentile scores vs peers 92/100 63/100 64/100 ARGX

Percentile Scorecard

ARGXBIIBBNTX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisARGXBIIBBNTX
Valuation 84 #99 of 625 92 #52 of 625 91 #58 of 625
Growth 94 #35 of 602 35 #392 of 602 14 #520 of 602
Profitability 98 #11 of 551 89 #64 of 551 77 #129 of 551
Financial Health – 35 #425 of 656 89 #71 of 656
Shareholder Returns – – 51 #179 of 365
Overall 92 63 64
  • ARGX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • BIIB ranked among 672 companies in Pharmaceuticals and Biotechnology
  • BNTX ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodARGXBIIBBNTXSPY
1 month -8.0%+11.0%-11.6% -0.2%
3 months +1.2%+22.9%-5.8% +3.9%
6 months +13.9%+37.8%-14.7% +8.2%
Year to date +4.9%+43.6%-8.6% +12.9%
1 year +6.3%+68.0%-17.9% +12.3%
3 years +91.9%+7.8%-4.5% +87.4%
3 years, per year +24.3%+2.5%-1.5% +23.3%
5 years +214.2%-4.6%-69.3% +67.9%
5 years, per year +25.8%-0.9%-21.1% +10.9%
10 years —-13.1%— +261.1%
10 years, per year —-1.4%— +13.7%

Risk

MeasureARGXBIIBBNTXSPY
Volatility, 1Y 36.9%34.0%46.6% 12.7%
Downside volatility, 1Y 34.6%32.3%46.5% 12.7%
Beta vs S&P 500, 1Y 0.390.260.95 1.00
Return / volatility, 1Y 0.172.00-0.38 0.97
Max drawdown, 5Y -38.2%-64.4%-78.4% -25.4%
From 52-week high -16.7%-0.4%-27.0% -1.2%
52-week high $1,058.90$253.84$119.34 $779.14
52-week low $663.93$147.86$83.89 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleARGXBIIBBNTX
P/E now vs peer median 28.8xmedian 17.2x 44.7xmedian 17.2x -10.7xmedian 17.2x
P/S now vs peer median 9.4xmedian 9.0x 3.7xmedian 9.0x 7.1xmedian 9.0x
EV/EBITDA now vs peer median —median 16.3x 23.4xmedian 16.3x -5.7xmedian 16.3x
P/FCF now vs peer median —median 18.7x 13.8xmedian 18.7x 21.2xmedian 18.7x
P/B now vs peer median —median 2.2x 2.0xmedian 2.2x 1.1xmedian 2.2x
PEG now vs peer median 0.27median 0.33 -1.37median 0.33 0.31median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsARGXBIIBBNTX
Revenue $5.82B $10.03B $3.09B
Gross profit $5.24B $7.42B $2.34B
Operating income $1.74B $1.01B -$2.33B
Net income $1.88B $834.60M -$1.97B
Free cash flow – $2.70B $1.04B
R&D $1.80B $2.01B $2.54B
EPS (diluted) $28.43 $5.61 $-8.13
Cash & equivalents – $1.29B $11.13B
Total debt – $7.29B $102.80M
Shares (diluted) 66.03M 148.70M 241.70M
Enterprise value $54.33B $22.68B -$25.42B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricARGXBIIBBNTX
P/E 28.8x 44.7x -10.7x
P/FCF – 13.8x 21.2x
P/Operating cash flow – 13.0x 27.8x
P/S 9.4x 3.7x 7.1x
P/B – 2.0x 1.1x
P/Tangible book – 7.0x 1.1x
EV/EBITDA – 23.4x -5.7x
EV/EBIT 31.4x 42.9x -3.7x
EV/Revenue 9.4x 4.3x 2.8x
EV/FCF – 16.1x 8.4x
EV/Operating cash flow – 15.1x 11.0x
PEG (3Y EPS CAGR) 0.27 -1.37 0.31

Growth

14 metrics
MetricARGXBIIBBNTX
Revenue growth (1Y) 61.5% 0.3% -1.1%
Revenue CAGR (3Y) 80.5% 0.2% -31.0%
Gross profit growth (1Y) 62.2% -1.6% -6.4%
Gross profit CAGR (3Y) 80.0% -1.1% -34.2%
Operating income growth (1Y) 120.6% -43.7% -142.6%
Operating income CAGR (3Y) 85.1% -31.3% -33.8%
Net income growth (1Y) 22.5% -45.5% -417.0%
Net income CAGR (3Y) 115.5% -32.1% -34.6%
EPS growth (1Y) 20.9% -46.2% -393.7%
EPS CAGR (3Y) 104.8% -32.6% -34.9%
Operating cash flow growth (1Y) – 36.0% 142.8%
Operating cash flow CAGR (3Y) – 26.3% -56.6%
Free cash flow growth (1Y) – 36.3% 164.1%
Free cash flow CAGR (3Y) – 33.0% -53.1%

Profitability

14 metrics
MetricARGXBIIBBNTX
Gross margin 90.0% 74.0% 75.5%
EBITDA margin – 18.5% -49.7%
Operating margin 29.9% 10.1% -75.2%
Pretax margin 32.6% 10.1% -61.4%
Net margin 32.3% 8.3% -63.5%
FCF margin – 26.9% 33.6%
Operating cash flow margin – 28.7% 25.6%
Return on equity – 4.5% -10.3%
Return on assets – 2.7% -9.0%
Return on invested capital – 3.3% -10.7%
Return on capital employed – 3.8% -9.9%
Asset turnover – 0.3x 0.1x
Cash conversion (OCF / net income) – 3.4x -0.4x
Stock comp / revenue – 3.0% 3.6%

Financial Health

11 metrics
MetricARGXBIIBBNTX
Debt / assets – 22.7% 0.4%
Debt / equity – 0.4x 0.0x
Net debt / EBITDA – 3.2x 8.7x
Debt / FCF – 2.7x 0.1x
Liabilities / assets – 41.3% 12.7%
Equity / assets – 58.7% 87.3%
Interest coverage 10,120x – -41.1x
Current ratio – 1.9x 65.1x
Quick ratio – 1.1x 50.7x
Cash ratio – 0.3x 50.0x
Altman Z-score – 3.15 6.31

Shareholder Returns

7 metrics
MetricARGXBIIBBNTX
Dividend yield – – –
Net buyback yield – – -2.9%
Shareholder yield – – -2.9%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusARGXBIIBBNTX
Forward P/E 28.8xFY2026 19.7xFY2026 –
EPS, next fiscal year $30.63FY2026 $12.81FY2026 $-6.21FY2026
EPS growth, next FY +56.5%FY2026 -16.2%FY2026 –
EPS growth, the year after +26.9% +36.5% –
Revenue, next fiscal year $6.08BFY2026 $9.96BFY2026 $1.90BFY2026
Revenue growth, next FY +43.1%FY2026 +0.7%FY2026 -43.7%FY2026
Revenue growth, the year after +22.9% +11.9% +11.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersARGXBIIBBNTX
Held by institutions 46.1% 96.4% 19.4%
Institutions holding 504 1,036 281
Change in shares held, QoQ -2.0% +6.0% -1.2%
Institutions buying 264 548 136
Institutions selling 160 294 73
Buyers to sellers 1.65 1.86 1.86

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ARGXBIIBBNTX
ARGX 1.00 0.21 0.23
BIIB 0.21 1.00 0.21
BNTX 0.23 0.21 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ARGX, BIIB and BNTX?

Argenx Se (ARGX) is the largest by market capitalisation: Argenx Se (ARGX) $54.33B, Biogen (BIIB) $36.02B, BioNTech SE (BNTX) $21.05B.

Which stock is cheaper, ARGX, BIIB and BNTX?

Argenx Se (ARGX) trades on the lowest price-to-earnings ratio (Argenx Se (ARGX) 28.9x, Biogen (BIIB) 43.2x, BioNTech SE (BNTX) -10.7x). On next year's consensus earnings, Biogen (BIIB) is cheapest (Argenx Se (ARGX) 28.8x, Biogen (BIIB) 19.7x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Argenx Se (ARGX) +61.5%, Biogen (BIIB) +0.3%, BioNTech SE (BNTX) -1.1%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Argenx Se (ARGX) 32.3%, Biogen (BIIB) 8.3%, BioNTech SE (BNTX) -63.5%). On return on invested capital, Biogen (BIIB) leads (Biogen (BIIB) 3.3%, BioNTech SE (BNTX) -10.7%).

Which stock has performed better?

Over the past year Biogen (BIIB) returned the most: Argenx Se (ARGX) +6.3%, Biogen (BIIB) +68.0%, BioNTech SE (BNTX) -17.9%. Over five years, Argenx Se (ARGX) compounded fastest (Argenx Se (ARGX) +25.8%/yr, Biogen (BIIB) -0.9%/yr, BioNTech SE (BNTX) -21.1%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Biogen (BIIB) has been the steadiest (Argenx Se (ARGX) 36.9%, Biogen (BIIB) 34.0%, BioNTech SE (BNTX) 46.6%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ARGX, BIIB and BNTX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Argenx Se (ARGX) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.