AMPH vs AMRX vs HSIC Stock Comparison

Amphastar Pharmaceuticals, Amneal Pharmaceuticals and Henry Schein Prices as of Oct 29, 2026 Peers: Industry group
HSIC Henry Schein Inc
$86.44 +1.7% 1M +38.7% 1Y
Market cap
$9.62B
P/E
23.9x
Revenue (TTM)
$13.60B
Div. yield
–
Drug Distribution Healthcare
2 wins

Head to Head

11 decided of 12

Amphastar Pharmaceuticals leads on 5 of the 12 questions below (Amphastar Pharmaceuticals 5, Amneal Pharmaceuticals 4, Henry Schein 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAMPHAMRXHSICLeader
Larger companyMarket capitalisation $1.20B $6.85B $9.62B HSIC
Cheaper on earningsLower P/E, profitable companies only 15.3x 43.5x 23.9x AMPH
Cheaper on forward earningsLower price / next fiscal year consensus EPS 8.7x 22.0x 15.0x AMPH
Faster revenue growthRevenue growth, trailing twelve months +1.0% +9.3% +6.5% AMRX
More profitableNet margin, trailing twelve months 10.8% 5.0% 3.0% AMPH
Better return on capitalReturn on invested capital 6.4% 17.4% 7.1% AMRX
Less leveragedLower net debt / EBITDA 1.8x 3.8x 3.3x AMPH
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +11.1% +104.7% +38.7% AMRX
Better 5-year returnAnnualised price return, 5 years +7.6%/yr +31.2%/yr +2.5%/yr AMRX
Less volatileAnnualised volatility, 1 year 54.3% 35.1% 25.6% HSIC
Higher overall scoreMean of the five percentile scores vs peers 73/100 70/100 55/100 AMPH

Percentile Scorecard

AMPHAMRXHSIC

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAMPHAMRXHSIC
Valuation 99 #9 of 624 92 #54 of 624 33 #17 of 25
Growth 43 #341 of 601 74 #158 of 601 39 #15 of 24
Profitability 88 #67 of 541 84 #87 of 541 83 #5 of 24
Financial Health 38 #405 of 647 12 #573 of 647 20 #21 of 26
Shareholder Returns 99 #4 of 359 87 #46 of 359 100 #1 of 16
Overall 73 70 55
  • AMPH ranked among 671 companies in Pharmaceuticals and Biotechnology
  • AMRX ranked among 671 companies in Pharmaceuticals and Biotechnology
  • HSIC ranked among 27 companies in Healthcare Payers and Distributors

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAMPHAMRXHSICSPY
1 month +0.9%+5.7%+1.7% +0.7%
3 months +32.1%+15.4%+1.5% +3.7%
6 months +22.6%+65.9%+15.9% +7.1%
Year to date +0.6%+69.4%+14.4% +12.8%
1 year +11.1%+104.7%+38.7% +11.9%
3 years -40.4%+450.3%+30.7% +85.2%
3 years, per year -15.9%+76.6%+9.3% +22.8%
5 years +44.2%+288.9%+13.2% +67.6%
5 years, per year +7.6%+31.2%+2.5% +10.9%
10 years +50.5%—+47.6% +262.0%
10 years, per year +4.2%—+4.0% +13.7%

Risk

MeasureAMPHAMRXHSICSPY
Volatility, 1Y 54.3%35.1%25.6% 12.7%
Downside volatility, 1Y 66.4%30.9%24.1% 12.6%
Beta vs S&P 500, 1Y 0.580.700.46 1.00
Return / volatility, 1Y 0.202.991.51 0.94
Max drawdown, 5Y -74.0%-78.2%-32.7% -25.4%
From 52-week high -8.4%-0.4%-4.9% -1.2%
52-week high $29.40$21.44$90.86 $779.14
52-week low $16.87$10.00$62.32 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAMPHAMRXHSIC
P/E now vs peer median 15.0xmedian 17.8x 43.3xmedian 17.8x 24.3xmedian 24.3x
P/S now vs peer median 1.6xmedian 9.1x 2.2xmedian 9.1x 0.7xmedian 0.3x
EV/EBITDA now vs peer median 8.4xmedian 15.0x 14.1xmedian 15.0x 12.9xmedian 12.9x
P/FCF now vs peer median 7.5xmedian 21.7x 82.0xmedian 21.7x 17.0xmedian 16.4x
P/B now vs peer median 1.5xmedian 2.2x 206.5xmedian 2.2x 2.5xmedian 2.5x
PEG now vs peer median -5.85median 0.35 0.18median 0.35 50.96median 1.36

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAMPHAMRXHSIC
Revenue $730.02M $3.12B $13.60B
Gross profit $348.11M $1.23B $4.26B
Operating income $114.29M $453.92M $680.00M
Net income $78.55M $215.32M $426.00M
Free cash flow $152.89M $83.11M $569.00M
R&D $94.57M $175.57M –
EPS (diluted) $1.78 $0.48 $3.52
Cash & equivalents $223.61M $127.64M –
Total debt $612.05M $2.67B $3.46B
Shares (diluted) 44.23M 328.10M 114.39M
Enterprise value $58.68M $6.04B $9.46B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAMPHAMRXHSIC
P/E 15.0x 43.3x 24.3x
P/FCF 7.5x 82.0x 17.0x
P/Operating cash flow 6.2x 34.0x 13.8x
P/S 1.6x 2.2x 0.7x
P/B 1.5x 206.5x 2.5x
P/Tangible book 1.6x -12.3x 3.4x
EV/EBITDA 8.4x 14.1x 12.9x
EV/EBIT 12.8x 20.6x 19.1x
EV/Revenue 2.0x 3.0x 1.0x
EV/FCF 9.6x 112.6x 22.8x
EV/Operating cash flow 7.9x 46.6x 18.5x
PEG (3Y EPS CAGR) -5.85 0.18 50.96

Growth

14 metrics
MetricAMPHAMRXHSIC
Revenue growth (1Y) 1.0% 9.3% 6.5%
Revenue CAGR (3Y) 10.5% 10.5% 2.6%
Gross profit growth (1Y) -3.4% 14.1% 6.4%
Gross profit CAGR (3Y) 8.0% 14.9% 3.4%
Operating income growth (1Y) -37.1% 20.6% 6.6%
Operating income CAGR (3Y) -4.5% 32.5% 1.1%
Net income growth (1Y) -41.7% 426.4% 6.0%
Net income CAGR (3Y) -8.3% 139.1% -4.5%
EPS growth (1Y) -36.5% 4,481% 11.1%
EPS CAGR (3Y) -2.6% 237.0% 0.5%
Operating cash flow growth (1Y) 15.6% -42.8% 36.7%
Operating cash flow CAGR (3Y) 12.1% 0.4% 2.3%
Free cash flow growth (1Y) 36.3% -69.3% 50.1%
Free cash flow CAGR (3Y) 15.0% -17.3% 2.3%

Profitability

14 metrics
MetricAMPHAMRXHSIC
Gross margin 47.7% 39.3% 31.3%
EBITDA margin 23.9% 21.3% 7.4%
Operating margin 15.7% 14.6% 5.0%
Pretax margin 14.0% 6.5% 4.1%
Net margin 10.8% 5.0% 3.0%
FCF margin 20.9% 2.7% 4.2%
Operating cash flow margin 25.3% 6.4% 5.1%
Return on equity 10.2% – 11.0%
Return on assets 4.6% 5.9% 3.8%
Return on invested capital 6.4% 17.4% 7.1%
Return on capital employed 8.0% 16.4% 8.7%
Asset turnover 0.4x 0.9x 1.2x
Cash conversion (OCF / net income) 2.4x 0.9x 1.6x
Stock comp / revenue 4.0% 1.1% 0.3%

Financial Health

11 metrics
MetricAMPHAMRXHSIC
Debt / assets 35.1% 70.7% 30.4%
Debt / equity 0.8x 80.9x 0.9x
Net debt / EBITDA 1.8x 3.8x 3.3x
Debt / FCF 4.0x 32.1x 6.1x
Liabilities / assets 55.9% 99.1% 66.5%
Equity / assets 44.1% 0.9% 33.5%
Interest coverage 4.4x – 4.3x
Current ratio 2.4x 2.2x 1.3x
Quick ratio 1.7x 1.3x 0.6x
Cash ratio 1.1x 0.1x 0.0x
Altman Z-score 2.16 2.50 2.67

Shareholder Returns

7 metrics
MetricAMPHAMRXHSIC
Dividend yield – – –
Net buyback yield 8.5% 0.0% 7.5%
Shareholder yield 8.5% 0.0% 7.5%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAMPHAMRXHSIC
Forward P/E 8.7xFY2026 22.0xFY2026 15.0xFY2026
EPS, next fiscal year $3.09FY2026 $0.97FY2026 $5.75FY2026
EPS growth, next FY -4.9%FY2026 +16.9%FY2026 +15.7%FY2026
EPS growth, the year after +9.4% +26.8% +8.2%
Revenue, next fiscal year $790.23MFY2026 $3.24BFY2026 $13.38BFY2026
Revenue growth, next FY +9.8%FY2026 +7.4%FY2026 +1.5%FY2026
Revenue growth, the year after -5.4% +12.4% +4.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAMPHAMRXHSIC
Held by institutions 64.8% 51.1% 100.0%
Institutions holding 209 310 565
Change in shares held, QoQ -11.7% +1.3% +2.1%
Institutions buying 96 182 245
Institutions selling 74 86 216
Buyers to sellers 1.30 2.12 1.13

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AMPHAMRXHSIC
AMPH 1.00 0.45 0.12
AMRX 0.45 1.00 0.17
HSIC 0.12 0.17 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, AMPH, AMRX and HSIC?

Henry Schein (HSIC) is the largest by market capitalisation: Amphastar Pharmaceuticals (AMPH) $1.20B, Amneal Pharmaceuticals (AMRX) $6.85B, Henry Schein (HSIC) $9.62B.

Which stock is cheaper, AMPH, AMRX and HSIC?

Amphastar Pharmaceuticals (AMPH) trades on the lowest price-to-earnings ratio (Amphastar Pharmaceuticals (AMPH) 15.3x, Amneal Pharmaceuticals (AMRX) 43.5x, Henry Schein (HSIC) 23.9x). On next year's consensus earnings, Amphastar Pharmaceuticals (AMPH) is cheapest (Amphastar Pharmaceuticals (AMPH) 8.7x, Amneal Pharmaceuticals (AMRX) 22.0x, Henry Schein (HSIC) 15.0x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Amneal Pharmaceuticals (AMRX) grew revenue fastest over the trailing twelve months: Amphastar Pharmaceuticals (AMPH) +1.0%, Amneal Pharmaceuticals (AMRX) +9.3%, Henry Schein (HSIC) +6.5%.

Which company is more profitable?

Amphastar Pharmaceuticals (AMPH) has the highest net margin (Amphastar Pharmaceuticals (AMPH) 10.8%, Amneal Pharmaceuticals (AMRX) 5.0%, Henry Schein (HSIC) 3.0%). On return on invested capital, Amneal Pharmaceuticals (AMRX) leads (Amphastar Pharmaceuticals (AMPH) 6.4%, Amneal Pharmaceuticals (AMRX) 17.4%, Henry Schein (HSIC) 7.1%).

Which stock has performed better?

Over the past year Amneal Pharmaceuticals (AMRX) returned the most: Amphastar Pharmaceuticals (AMPH) +11.1%, Amneal Pharmaceuticals (AMRX) +104.7%, Henry Schein (HSIC) +38.7%. Over five years, Amneal Pharmaceuticals (AMRX) compounded fastest (Amphastar Pharmaceuticals (AMPH) +7.6%/yr, Amneal Pharmaceuticals (AMRX) +31.2%/yr, Henry Schein (HSIC) +2.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Henry Schein (HSIC) has been the steadiest (Amphastar Pharmaceuticals (AMPH) 54.3%, Amneal Pharmaceuticals (AMRX) 35.1%, Henry Schein (HSIC) 25.6%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, AMPH, AMRX and HSIC?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amphastar Pharmaceuticals (AMPH) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.