AMGN vs REGN vs ROIV Stock Comparison

Amgen, Regeneron Pharmaceuticals and Roivant Sciences Prices as of Oct 23, 2026 Peers: Industry group
AMGN Amgen Inc
$439.26 +8.2% 1M +50.0% 1Y
Market cap
$240.04B
P/E
27.5x
Revenue (TTM)
$38.10B
Div. yield
0.02%
Biotechnology Healthcare
3 wins
ROIV Roivant Sciences Ltd.
$36.49 -0.9% 1M +101.4% 1Y
Market cap
$25.97B
P/E
–
Revenue (TTM)
$7.53M
Div. yield
–
Biotechnology Healthcare
2 wins

Head to Head

11 decided of 12

Regeneron Pharmaceuticals leads on 6 of the 12 questions below (Regeneron Pharmaceuticals 6, Amgen 3, Roivant Sciences 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAMGNREGNROIVLeader
Larger companyMarket capitalisation $240.04B $83.00B $25.97B AMGN
Cheaper on earningsLower P/E, profitable companies only 27.5x 19.2x -97.5x REGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 20.1x 14.4x — REGN
Faster revenue growthRevenue growth, trailing twelve months +9.1% +9.3% -67.6% REGN
More profitableNet margin, trailing twelve months 23.0% 27.9% -3,535.0% REGN
Better return on capitalReturn on invested capital 14.3% 9.6% — AMGN
Less leveragedLower net debt / EBITDA 2.7x -1.4x — REGN
Higher dividend yieldTrailing dividend yield 0.02% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +50.0% +39.8% +101.4% ROIV
Better 5-year returnAnnualised price return, 5 years +16.0%/yr +7.1%/yr +40.0%/yr ROIV
Less volatileAnnualised volatility, 1 year 29.6% 32.8% 45.3% AMGN
Higher overall scoreMean of the five percentile scores vs peers 66/100 72/100 65/100 REGN

Percentile Scorecard

AMGNREGNROIV

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAMGNREGNROIV
Valuation 85 #92 of 624 88 #73 of 624 63 #233 of 624
Growth 62 #231 of 603 42 #352 of 603 49 #308 of 603
Profitability 94 #32 of 555 90 #54 of 555 30 #388 of 555
Financial Health 22 #512 of 657 74 #174 of 657 93 #47 of 657
Shareholder Returns 68 #118 of 370 65 #131 of 370 90 #38 of 370
Overall 66 72 65
  • AMGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • REGN ranked among 671 companies in Pharmaceuticals and Biotechnology
  • ROIV ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAMGNREGNROIVSPY
1 month +8.2%+0.4%-0.9% -1.0%
3 months +16.8%+22.7%+4.2% +2.9%
6 months +27.5%+7.1%+33.1% +6.4%
Year to date +34.2%+4.3%+68.2% +11.4%
1 year +50.0%+39.8%+101.4% +13.1%
3 years +59.1%+0.1%+318.5% +79.4%
3 years, per year +16.7%+0.0%+61.2% +21.5%
5 years +109.9%+40.6%+436.6% +67.7%
5 years, per year +16.0%+7.1%+40.0% +10.9%
10 years +177.1%+121.4%— +255.2%
10 years, per year +10.7%+8.3%— +13.5%

Risk

MeasureAMGNREGNROIVSPY
Volatility, 1Y 29.6%32.8%45.3% 12.7%
Downside volatility, 1Y 27.6%30.0%32.6% 12.7%
Beta vs S&P 500, 1Y 0.440.470.99 1.00
Return / volatility, 1Y 1.691.212.24 1.03
Max drawdown, 5Y -26.7%-59.8%-79.2% -25.4%
From 52-week high -1.8%-5.5%-12.7% -2.5%
52-week high $447.28$852.03$41.81 $779.14
52-week low $291.16$575.69$18.12 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAMGNREGNROIV
P/E now vs peer median 27.1xmedian 17.2x 19.1xmedian 17.2x -98.8xmedian 17.2x
P/S now vs peer median 6.2xmedian 8.8x 5.3xmedian 8.8x 3,501xmedian 8.8x
EV/EBITDA now vs peer median 17.4xmedian 16.0x 17.6xmedian 16.0x -38.0xmedian 16.0x
P/FCF now vs peer median 23.3xmedian 17.8x 22.0xmedian 17.8x -32.1xmedian 17.8x
P/B now vs peer median 20.3xmedian 2.1x 2.6xmedian 2.1x 5.4xmedian 2.1x
PEG now vs peer median 10.23median 0.32 7.19median 0.32 -2.92median 0.32

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAMGNREGNROIV
Revenue $38.10B $15.53B $7.53M
Gross profit $26.48B $13.18B $6.12M
Operating income $11.43B $3.84B -$596.14M
Net income $8.74B $4.33B -$414.60M
Free cash flow $10.18B $3.76B -$821.06M
R&D $7.63B $6.28B $730.91M
EPS (diluted) $16.07 $40.84 $-0.37
Cash & equivalents $13.99B $2.46B $1.25B
Total debt $57.30B $7.94B –
Shares (diluted) 544.00M 106.00M 720.78M
Enterprise value $195.44B $49.21B $8.92B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAMGNREGNROIV
P/E 27.1x 19.1x -98.8x
P/FCF 23.3x 22.0x -32.1x
P/Operating cash flow 19.0x 17.7x -32.3x
P/S 6.2x 5.3x 3,501x
P/B 20.3x 2.6x 5.4x
P/Tangible book -27.0x 2.7x 5.4x
EV/EBITDA 17.4x 17.6x -38.0x
EV/EBIT 24.6x 20.0x -37.8x
EV/Revenue 7.4x 4.9x 2,991x
EV/FCF 27.6x 20.4x -27.4x
EV/Operating cash flow 22.5x 16.4x -27.6x
PEG (3Y EPS CAGR) 10.23 7.19 -2.92

Growth

14 metrics
MetricAMGNREGNROIV
Revenue growth (1Y) 9.1% 9.3% -67.6%
Revenue CAGR (3Y) 12.7% 7.0% -46.4%
Gross profit growth (1Y) 17.6% 8.4% -72.7%
Gross profit CAGR (3Y) 10.3% 6.4% -47.9%
Operating income growth (1Y) 39.5% 0.1% 49.7%
Operating income CAGR (3Y) 6.4% -3.9% 12.9%
Net income growth (1Y) 32.1% -2.9% 34.9%
Net income CAGR (3Y) 3.1% 0.2% 26.5%
EPS growth (1Y) 31.4% -0.5% 48.8%
EPS CAGR (3Y) 2.7% 2.7% 33.9%
Operating cash flow growth (1Y) 3.9% -1.3% 4.1%
Operating cash flow CAGR (3Y) 4.9% -0.4% 1.0%
Free cash flow growth (1Y) -4.1% -2.4% 4.4%
Free cash flow CAGR (3Y) 1.7% -3.3% 1.0%

Profitability

14 metrics
MetricAMGNREGNROIV
Gross margin 69.5% 84.9% 81.2%
EBITDA margin 42.2% 28.1% -7,877%
Operating margin 30.0% 24.7% -7,915%
Pretax margin 27.0% 33.3% -3,849%
Net margin 23.0% 27.9% -3,535%
FCF margin 26.7% 24.2% -10,901%
Operating cash flow margin 32.8% 30.1% -10,840%
Return on equity 83.8% 13.7% -8.1%
Return on assets 9.3% 10.5% -7.5%
Return on invested capital 14.3% 9.6% –
Return on capital employed 16.7% 10.7% -11.4%
Asset turnover 0.4x 0.4x 0.0x
Cash conversion (OCF / net income) 1.4x 1.1x 2.0x
Stock comp / revenue 1.3% 6.4% 4,611%

Financial Health

11 metrics
MetricAMGNREGNROIV
Debt / assets 59.9% 4.8% –
Debt / equity 4.9x 0.1x –
Net debt / EBITDA 2.7x -1.4x –
Debt / FCF 5.6x 0.5x –
Liabilities / assets 87.8% 24.0% 7.2%
Equity / assets 12.2% 76.0% 92.8%
Interest coverage 4.3x 69.4x –
Current ratio 1.4x 3.3x 16.7x
Quick ratio 0.9x 2.6x 13.5x
Cash ratio 0.5x 1.4x 13.5x
Altman Z-score 2.28 7.27 41.54

Shareholder Returns

7 metrics
MetricAMGNREGNROIV
Dividend yield 2.3% 0.5% –
Net buyback yield – 3.1% 0.0%
Shareholder yield 2.3% 3.5% 0.0%
Payout ratio (earnings) 60.4% – –
Payout ratio (FCF) 51.9% – –
Dividend growth (1Y) 6.3% – –
Dividend CAGR (3Y) 6.7% – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAMGNREGNROIV
Forward P/E 20.1xFY2026 14.4xFY2026 –
EPS, next fiscal year $21.80FY2026 $55.81FY2026 $-1.43FY2026
EPS growth, next FY -0.2%FY2026 +26.0%FY2026 –
EPS growth, the year after +7.3% +16.5% –
Revenue, next fiscal year $41.51BFY2026 $16.91BFY2026 $55.64MFY2026
Revenue growth, next FY +12.9%FY2026 +17.9%FY2026 +573.6%FY2026
Revenue growth, the year after +2.2% +14.0% +680.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAMGNREGNROIV
Held by institutions 82.7% 66.2% 77.0%
Institutions holding 3,159 1,325 498
Change in shares held, QoQ +4.5% +3.8% +5.1%
Institutions buying 1,451 604 303
Institutions selling 1,217 534 138
Buyers to sellers 1.19 1.13 2.20

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AMGNREGNROIV
AMGN 1.00 0.49 0.08
REGN 0.49 1.00 0.18
ROIV 0.08 0.18 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, AMGN, REGN and ROIV?

Amgen (AMGN) is the largest by market capitalisation: Amgen (AMGN) $240.04B, Regeneron Pharmaceuticals (REGN) $83.00B, Roivant Sciences (ROIV) $25.97B.

Which stock is cheaper, AMGN, REGN and ROIV?

Regeneron Pharmaceuticals (REGN) trades on the lowest price-to-earnings ratio (Amgen (AMGN) 27.5x, Regeneron Pharmaceuticals (REGN) 19.2x, Roivant Sciences (ROIV) -97.5x). On next year's consensus earnings, Regeneron Pharmaceuticals (REGN) is cheapest (Amgen (AMGN) 20.1x, Regeneron Pharmaceuticals (REGN) 14.4x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Regeneron Pharmaceuticals (REGN) grew revenue fastest over the trailing twelve months: Amgen (AMGN) +9.1%, Regeneron Pharmaceuticals (REGN) +9.3%, Roivant Sciences (ROIV) -67.6%.

Which company is more profitable?

Regeneron Pharmaceuticals (REGN) has the highest net margin (Amgen (AMGN) 23.0%, Regeneron Pharmaceuticals (REGN) 27.9%, Roivant Sciences (ROIV) -3,535.0%). On return on invested capital, Amgen (AMGN) leads (Amgen (AMGN) 14.3%, Regeneron Pharmaceuticals (REGN) 9.6%).

Which stock has performed better?

Over the past year Roivant Sciences (ROIV) returned the most: Amgen (AMGN) +50.0%, Regeneron Pharmaceuticals (REGN) +39.8%, Roivant Sciences (ROIV) +101.4%. Over five years, Roivant Sciences (ROIV) compounded fastest (Amgen (AMGN) +16.0%/yr, Regeneron Pharmaceuticals (REGN) +7.1%/yr, Roivant Sciences (ROIV) +40.0%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Amgen (AMGN) 0.02%, Regeneron Pharmaceuticals (REGN) 0.00%, Roivant Sciences (ROIV) 0.00%. Regeneron Pharmaceuticals (REGN) and Roivant Sciences (ROIV) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Amgen (AMGN) has been the steadiest (Amgen (AMGN) 29.6%, Regeneron Pharmaceuticals (REGN) 32.8%, Roivant Sciences (ROIV) 45.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, AMGN, REGN and ROIV?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Regeneron Pharmaceuticals (REGN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.