ADPT vs CAI vs DGX Stock Comparison

Adaptive Biotechnologies, Caris Life Sciences and Quest Diagnostics Prices as of Oct 26, 2026 Peers: Industry group
DGX Quest Diagnostics Inc
$242.92 +2.8% 1M +33.3% 1Y
Market cap
$26.58B
P/E
23.5x
Revenue (TTM)
$11.84B
Div. yield
0.01%
Diagnostic Labs Healthcare
5 wins

Head to Head

11 decided of 12

Quest Diagnostics leads on 5 of the 12 questions below (Quest Diagnostics 5, Caris Life Sciences 5, Adaptive Biotechnologies 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionADPTCAIDGXLeader
Larger companyMarket capitalisation $4.40B $9.53B $26.58B DGX
Cheaper on earningsLower P/E, profitable companies only -68.8x 90.6x 23.5x DGX
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 295.1x 22.2x DGX
Faster revenue growthRevenue growth, trailing twelve months +50.1% +85.4% +9.1% CAI
More profitableNet margin, trailing twelve months -20.7% 10.6% 9.5% CAI
Better return on capitalReturn on invested capital — 15.6% 9.9% CAI
Less leveragedLower net debt / EBITDA — -2.2x 2.1x CAI
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.01% –
Better 1-year returnPrice return, last 12 months +52.6% +4.5% +33.3% ADPT
Better 5-year returnAnnualised price return, 5 years -4.1%/yr — +11.0%/yr DGX
Less volatileAnnualised volatility, 1 year 67.8% 69.6% 23.8% DGX
Higher overall scoreMean of the five percentile scores vs peers 42/100 69/100 64/100 CAI

Percentile Scorecard

ADPTCAIDGX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisADPTCAIDGX
Valuation 14 #80 of 93 23 #72 of 93 71 #28 of 93
Growth 85 #14 of 88 99 #2 of 88 40 #53 of 88
Profitability 23 #67 of 87 87 #12 of 87 77 #21 of 87
Financial Health 65 #36 of 100 82 #19 of 100 56 #45 of 100
Shareholder Returns 24 #43 of 56 53 #27 of 56 76 #14 of 56
Overall 42 69 64
  • ADPT ranked among 103 companies in Healthcare Providers
  • CAI ranked among 103 companies in Healthcare Providers
  • DGX ranked among 103 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodADPTCAIDGXSPY
1 month -10.7%+1.5%+2.8% -0.8%
3 months +16.5%+107.7%+4.7% +3.5%
6 months +84.9%+62.9%+23.5% +7.0%
Year to date +61.8%+20.3%+40.0% +12.2%
1 year +52.6%+4.5%+33.3% +13.0%
3 years +518.1%—+90.3% +86.3%
3 years, per year +83.6%—+23.9% +23.1%
5 years -18.8%—+68.8% +68.6%
5 years, per year -4.1%—+11.0% +11.0%
10 years ——+203.1% +258.0%
10 years, per year ——+11.7% +13.6%

Risk

MeasureADPTCAIDGXSPY
Volatility, 1Y 67.8%69.6%23.8% 12.7%
Downside volatility, 1Y 63.7%69.3%18.8% 12.7%
Beta vs S&P 500, 1Y 1.661.38-0.09 1.00
Return / volatility, 1Y 0.780.061.40 1.02
Max drawdown, 5Y -93.6%-63.0%-30.3% -25.4%
From 52-week high -12.0%0.0%-1.8% -1.8%
52-week high $29.84$32.46$247.47 $779.14
52-week low $12.41$14.55$173.49 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleADPTCAIDGX
P/E now vs peer median -65.8xmedian 25.1x 87.3xmedian 25.1x 23.7xmedian 25.1x
P/S now vs peer median 13.6xmedian 1.6x 9.3xmedian 1.6x 2.3xmedian 1.6x
EV/EBITDA now vs peer median -178.2xmedian 14.5x 48.7xmedian 14.5x 13.6xmedian 14.5x
P/FCF now vs peer median -173.9xmedian 22.4x 74.0xmedian 22.4x 19.4xmedian 22.4x
P/B now vs peer median 27.7xmedian 3.1x 15.5xmedian 3.1x 3.4xmedian 3.1x
PEG now vs peer median -2.00median 0.66 —median 0.66 1.62median 0.66

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsADPTCAIDGX
Revenue $308.08M $989.61M $11.84B
Gross profit $232.83M $689.36M $3.92B
Operating income -$37.46M $153.26M $1.72B
Net income -$63.99M $105.14M $1.18B
Free cash flow -$24.03M $123.96M $1.38B
R&D $88.21M $117.14M –
EPS (diluted) $-0.40 $0.37 $10.08
Cash & equivalents $169.87M $690.92M $797.00M
Total debt – $393.15M $5.55B
Shares (diluted) 159.86M 282.89M 112.00M
Enterprise value $3.39B $6.35B $24.34B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricADPTCAIDGX
P/E -65.8x 87.3x 23.7x
P/FCF -173.9x 74.0x 19.4x
P/Operating cash flow -198.9x 54.4x 13.7x
P/S 13.6x 9.3x 2.3x
P/B 27.7x 15.5x 3.4x
P/Tangible book 27.9x 15.5x 4.2x
EV/EBITDA -178.2x 48.7x 13.6x
EV/EBIT -102.4x 57.2x 18.3x
EV/Revenue 12.4x 8.9x 2.7x
EV/FCF -159.5x 70.8x 22.9x
EV/Operating cash flow -182.5x 52.0x 16.1x
PEG (3Y EPS CAGR) -2.00 – 1.62

Growth

14 metrics
MetricADPTCAIDGX
Revenue growth (1Y) 50.1% 85.4% 9.1%
Revenue CAGR (3Y) 17.6% – 8.4%
Gross profit growth (1Y) 71.8% 141.2% 8.5%
Gross profit CAGR (3Y) 24.2% – 8.4%
Operating income growth (1Y) 69.1% 188.2% 12.5%
Operating income CAGR (3Y) 41.8% – 15.1%
Net income growth (1Y) 47.2% 137.7% 15.0%
Net income CAGR (3Y) 30.5% – 12.9%
EPS growth (1Y) 49.9% 103.0% 17.6%
EPS CAGR (3Y) 32.9% – 14.6%
Operating cash flow growth (1Y) 73.9% 227.3% 3.5%
Operating cash flow CAGR (3Y) 48.6% – 21.8%
Free cash flow growth (1Y) 71.0% 188.2% -1.3%
Free cash flow CAGR (3Y) 47.9% – 32.1%

Profitability

14 metrics
MetricADPTCAIDGX
Gross margin 75.6% 69.7% 33.1%
EBITDA margin -7.0% 18.2% 19.5%
Operating margin -12.2% 15.5% 14.6%
Pretax margin -13.1% 10.6% 12.6%
Net margin -20.7% 10.6% 9.5%
FCF margin -7.8% 12.5% 11.6%
Operating cash flow margin -6.8% 17.0% 16.5%
Return on equity -34.1% 17.7% 15.0%
Return on assets -11.2% 8.8% 6.9%
Return on invested capital – 15.6% 9.9%
Return on capital employed -7.7% 15.3% 11.3%
Asset turnover 0.5x 0.8x 0.7x
Cash conversion (OCF / net income) 0.3x 1.6x 1.7x
Stock comp / revenue 15.9% 6.6% 0.7%

Financial Health

11 metrics
MetricADPTCAIDGX
Debt / assets – 32.0% 32.2%
Debt / equity – 0.7x 0.7x
Net debt / EBITDA – -2.2x 2.1x
Debt / FCF – 3.2x 4.0x
Liabilities / assets 76.5% 51.9% 53.8%
Equity / assets 23.5% 48.1% 46.2%
Interest coverage -3.3x 3.3x 6.5x
Current ratio 4.8x 5.5x 1.7x
Quick ratio 4.5x 4.8x 1.4x
Cash ratio 3.9x 4.1x 0.4x
Altman Z-score 2.92 7.79 3.70

Shareholder Returns

7 metrics
MetricADPTCAIDGX
Dividend yield – – 1.4%
Net buyback yield -0.5% 0.1% 1.2%
Shareholder yield -0.5% 0.1% 2.6%
Payout ratio (earnings) – – 31.3%
Payout ratio (FCF) – – 26.8%
Dividend growth (1Y) – – 6.3%
Dividend CAGR (3Y) – – 6.1%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusADPTCAIDGX
Forward P/E – 295.1xFY2026 22.2xFY2026
EPS, next fiscal year $-0.57FY2026 $0.11FY2026 $10.96FY2026
EPS growth, next FY – – +11.3%FY2026
EPS growth, the year after – +236.4% +6.8%
Revenue, next fiscal year $284.03MFY2026 $1.06BFY2026 $11.25BFY2026
Revenue growth, next FY +2.5%FY2026 +30.1%FY2026 +1.9%FY2026
Revenue growth, the year after +33.8% +21.6% +7.7%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersADPTCAIDGX
Held by institutions 97.2% 52.0% 94.4%
Institutions holding 299 245 1,096
Change in shares held, QoQ +2.5% -6.3% +2.7%
Institutions buying 160 175 549
Institutions selling 87 47 341
Buyers to sellers 1.84 3.72 1.61

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ADPTCAIDGX
ADPT 1.00 0.44 0.23
CAI 0.44 1.00 0.22
DGX 0.23 0.22 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ADPT, CAI and DGX?

Quest Diagnostics (DGX) is the largest by market capitalisation: Adaptive Biotechnologies (ADPT) $4.40B, Caris Life Sciences (CAI) $9.53B, Quest Diagnostics (DGX) $26.58B.

Which stock is cheaper, ADPT, CAI and DGX?

Quest Diagnostics (DGX) trades on the lowest price-to-earnings ratio (Adaptive Biotechnologies (ADPT) -68.8x, Caris Life Sciences (CAI) 90.6x, Quest Diagnostics (DGX) 23.5x). On next year's consensus earnings, Quest Diagnostics (DGX) is cheapest (Caris Life Sciences (CAI) 295.1x, Quest Diagnostics (DGX) 22.2x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Caris Life Sciences (CAI) grew revenue fastest over the trailing twelve months: Adaptive Biotechnologies (ADPT) +50.1%, Caris Life Sciences (CAI) +85.4%, Quest Diagnostics (DGX) +9.1%.

Which company is more profitable?

Caris Life Sciences (CAI) has the highest net margin (Adaptive Biotechnologies (ADPT) -20.7%, Caris Life Sciences (CAI) 10.6%, Quest Diagnostics (DGX) 9.5%). On return on invested capital, Caris Life Sciences (CAI) leads (Caris Life Sciences (CAI) 15.6%, Quest Diagnostics (DGX) 9.9%).

Which stock has performed better?

Over the past year Adaptive Biotechnologies (ADPT) returned the most: Adaptive Biotechnologies (ADPT) +52.6%, Caris Life Sciences (CAI) +4.5%, Quest Diagnostics (DGX) +33.3%. Over five years, Quest Diagnostics (DGX) compounded fastest (Adaptive Biotechnologies (ADPT) -4.1%/yr, Quest Diagnostics (DGX) +11.0%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Adaptive Biotechnologies (ADPT) 0.00%, Caris Life Sciences (CAI) 0.00%, Quest Diagnostics (DGX) 0.01%. Adaptive Biotechnologies (ADPT) and Caris Life Sciences (CAI) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Quest Diagnostics (DGX) has been the steadiest (Adaptive Biotechnologies (ADPT) 67.8%, Caris Life Sciences (CAI) 69.6%, Quest Diagnostics (DGX) 23.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ADPT, CAI and DGX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Quest Diagnostics (DGX) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.