AZN vs TAK Stock Comparison

Astrazeneca and Takeda Pharmaceutical Prices as of Oct 26, 2026 Peers: Industry group
AZN Astrazeneca Plc
$172.00 +3.2% 1M +3.3% 1Y
Market cap
$266.60B
P/E
25.5x
Revenue (TTM)
$58.67B
Div. yield
1.39%
Pharmaceuticals Healthcare
8 wins

Head to Head

12 decided of 12

Astrazeneca leads on 8 of the 12 questions below (Astrazeneca 8, Takeda Pharmaceutical 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionAZNTAKLeader
Larger companyMarket capitalisation $266.60B $65.02B AZN
Cheaper on earningsLower P/E, profitable companies only 25.5x 112.1x AZN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 17.2x 51.1x AZN
Faster revenue growthRevenue growth, trailing twelve months +9.4% +0.7% AZN
More profitableNet margin, trailing twelve months 17.8% 1.2% AZN
Better return on capitalReturn on invested capital 23.3% 3.5% AZN
Less leveragedLower net debt / EBITDA 1.4x 3.5x AZN
Higher dividend yieldTrailing dividend yield 1.39% 1.52% TAK
Better 1-year returnPrice return, last 12 months +3.3% +45.8% TAK
Better 5-year returnAnnualised price return, 5 years +6.8%/yr +8.1%/yr TAK
Less volatileAnnualised volatility, 1 year 27.4% 21.5% TAK
Higher overall scoreMean of the five percentile scores vs peers 71/100 64/100 AZN

Percentile Scorecard

AZNTAK

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisAZNTAK
Valuation 82 #51 of 275 95 #15 of 275
Growth 68 #83 of 253 23 #196 of 253
Profitability 95 #13 of 224 86 #33 of 224
Financial Health 41 #176 of 296 37 #187 of 296
Shareholder Returns 71 #37 of 126 80 #26 of 126
Overall 71 64
  • AZN ranked among 305 companies in Pharmaceuticals and Biotechnology
  • TAK ranked among 305 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodAZNTAKSPY
1 month +3.2%+8.3% -0.8%
3 months +1.4%+17.1% +3.5%
6 months -8.3%+24.9% +7.0%
Year to date -6.5%+31.0% +12.2%
1 year +3.3%+45.8% +13.0%
3 years +39.0%+51.7% +86.3%
3 years, per year +11.6%+14.9% +23.1%
5 years +39.2%+47.8% +68.6%
5 years, per year +6.8%+8.1% +11.0%
10 years +190.6%-11.4% +258.0%
10 years, per year +11.3%-1.2% +13.6%

Risk

MeasureAZNTAKSPY
Volatility, 1Y 27.4%21.5% 12.7%
Downside volatility, 1Y 27.3%20.3% 12.7%
Beta vs S&P 500, 1Y 0.220.11 1.00
Return / volatility, 1Y 0.122.13 1.02
Max drawdown, 5Y -27.9%-26.4% -25.4%
From 52-week high -17.9%0.0% -1.8%
52-week high $209.48$20.43 $779.14
52-week low $155.60$13.23 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleAZNTAK
P/E now vs peer median 25.5xmedian 10.4x 112.1xmedian 10.4x
P/S now vs peer median 4.5xmedian 6.4x 1.4xmedian 6.4x
EV/EBITDA now vs peer median 14.5xmedian 10.7x 12.4xmedian 10.7x
P/FCF now vs peer median 25.0xmedian 12.5x 12.5xmedian 12.5x
P/B now vs peer median 5.3xmedian 1.6x 1.4xmedian 1.6x
PEG now vs peer median 1.33median 0.29 -2.76median 0.29

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsAZNTAK
Revenue $58.67B $46.49B
Gross profit $50.25B $30.58B
Operating income $13.97B $2.71B
Net income $10.45B -$1.04B
Free cash flow $10.67B $5.20B
R&D $15.07B $4.53B
EPS (diluted) $6.69 $0.18
Cash & equivalents $4.90B $2.85B
Total debt $106.76B $126.30B
Shares (diluted) 1.56B 3.15B
Enterprise value $240.36B $41.39B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricAZNTAK
P/E 25.5x 112.1x
P/FCF 25.0x 12.5x
P/Operating cash flow 19.5x 10.4x
P/S 4.5x 1.4x
P/B 5.3x 1.4x
P/Tangible book 21.1x 2.5x
EV/EBITDA 14.5x 12.4x
EV/EBIT 21.0x 33.3x
EV/Revenue 5.0x 1.9x
EV/FCF 27.6x 17.4x
EV/Operating cash flow 21.5x 14.4x
PEG (3Y EPS CAGR) 1.33 -2.76

Growth

14 metrics
MetricAZNTAK
Revenue growth (1Y) 9.4% 0.7%
Revenue CAGR (3Y) 10.6% 14.8%
Gross profit growth (1Y) 9.3% -0.8%
Gross profit CAGR (3Y) 13.1% -0.2%
Operating income growth (1Y) 23.4% -43.4%
Operating income CAGR (3Y) 23.9% -14.3%
Net income growth (1Y) 25.9% -209.1%
Net income CAGR (3Y) 19.2% -35.3%
EPS growth (1Y) 26.0% -75.7%
EPS CAGR (3Y) 19.2% -40.6%
Operating cash flow growth (1Y) 2.3% -14.8%
Operating cash flow CAGR (3Y) 13.7% -4.4%
Free cash flow growth (1Y) -4.5% -13.3%
Free cash flow CAGR (3Y) 8.5% -5.2%

Profitability

14 metrics
MetricAZNTAK
Gross margin 85.6% 65.8%
EBITDA margin 34.6% 15.6%
Operating margin 23.8% 5.8%
Pretax margin 21.5% 2.6%
Net margin 17.8% 1.2%
FCF margin 18.2% 11.2%
Operating cash flow margin 23.3% 13.5%
Return on equity 21.4% 1.2%
Return on assets 9.1% 0.6%
Return on invested capital 23.3% 3.5%
Return on capital employed 16.8% 3.0%
Asset turnover 0.5x 0.5x
Cash conversion (OCF / net income) 1.3x -6.0x
Stock comp / revenue – 1.0%

Financial Health

11 metrics
MetricAZNTAK
Debt / assets 27.9% 32.0%
Debt / equity 0.6x 0.7x
Net debt / EBITDA 1.4x 3.5x
Debt / FCF 3.0x 6.0x
Liabilities / assets 56.5% 51.7%
Equity / assets 43.5% 48.3%
Interest coverage 15.9x 0.8x
Current ratio 0.9x 3.2x
Quick ratio 0.7x 1.9x
Cash ratio 0.2x 0.9x
Altman Z-score 3.46 1.58

Shareholder Returns

7 metrics
MetricAZNTAK
Dividend yield 1.4% 1.5%
Net buyback yield 0.0% 1.0%
Shareholder yield 1.4% 2.5%
Payout ratio (earnings) – –
Payout ratio (FCF) – –
Dividend growth (1Y) – –
Dividend CAGR (3Y) – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusAZNTAK
Forward P/E 17.2xFY2026 51.1xFY2026
EPS, next fiscal year $10.00FY2026 $0.40FY2026
EPS growth, next FY +9.2%FY2026 +5.3%FY2026
EPS growth, the year after +6.2% +62.5%
Revenue, next fiscal year $59.02BFY2026 $28.25BFY2026
Revenue growth, next FY +0.5%FY2026 -0.8%FY2026
Revenue growth, the year after +7.9% +11.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersAZNTAK
Held by institutions 52.1% 3.3%
Institutions holding 1,496 378
Change in shares held, QoQ +7.8% +6.2%
Institutions buying 808 212
Institutions selling 468 98
Buyers to sellers 1.73 2.16

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

AZNTAK
AZN 1.00 0.52
TAK 0.52 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, AZN and TAK?

Astrazeneca (AZN) is the largest by market capitalisation: Astrazeneca (AZN) $266.60B, Takeda Pharmaceutical (TAK) $65.02B.

Which stock is cheaper, AZN and TAK?

Astrazeneca (AZN) trades on the lowest price-to-earnings ratio (Astrazeneca (AZN) 25.5x, Takeda Pharmaceutical (TAK) 112.1x). On next year's consensus earnings, Astrazeneca (AZN) is cheapest (Astrazeneca (AZN) 17.2x, Takeda Pharmaceutical (TAK) 51.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Astrazeneca (AZN) grew revenue fastest over the trailing twelve months: Astrazeneca (AZN) +9.4%, Takeda Pharmaceutical (TAK) +0.7%.

Which company is more profitable?

Astrazeneca (AZN) has the highest net margin (Astrazeneca (AZN) 17.8%, Takeda Pharmaceutical (TAK) 1.2%). On return on invested capital, Astrazeneca (AZN) leads (Astrazeneca (AZN) 23.3%, Takeda Pharmaceutical (TAK) 3.5%).

Which stock has performed better?

Over the past year Takeda Pharmaceutical (TAK) returned the most: Astrazeneca (AZN) +3.3%, Takeda Pharmaceutical (TAK) +45.8%. Over five years, Takeda Pharmaceutical (TAK) compounded fastest (Astrazeneca (AZN) +6.8%/yr, Takeda Pharmaceutical (TAK) +8.1%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Takeda Pharmaceutical (TAK) has the highest dividend yield: Astrazeneca (AZN) 1.39%, Takeda Pharmaceutical (TAK) 1.52%.

Which stock is riskier?

By one-year price volatility, Takeda Pharmaceutical (TAK) has been the steadiest (Astrazeneca (AZN) 27.4%, Takeda Pharmaceutical (TAK) 21.5%). Volatility measures how widely the price swings, not the risk of the business.

Do AZN and TAK move together?

Their daily returns over the past year have a correlation of 0.52, a moderate positive relationship. Holding both diversifies more than two closely linked stocks would.

Which is the better stock, AZN and TAK?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Astrazeneca (AZN) leads on 8. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.