COMPASS Pathways plc (CMPS) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

95,636,806Shares Outstanding

7,243,433Shares held by institutions

$55,267,394Value of institutional holdings

57.47%Institutional ownership %

9.90%Shares Changed QoQ

157No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

According to SEC filings for the period ending December 2025, COMPASS Pathways plc (NASDAQ:CMPS) is held by 157 institutional firms.

COMPASS Pathways saw its institutional ownership percentage fell to 57.5% in December 2025 from 59.1% in September 2025.
In percentage terms, this reflects as a holdings change of 9.90% quarter on quarter, and an increase of 22.66% year over year.
Of these 157 institutional investors, 67 increased their holdings in COMPASS Pathways, while 39 of them reduced positions, and 51 investors maintained their exposure.
The aggregate institutional position in COMPASS Pathways now stands at 54.96Mn shares as of December 2025, after investors increased their holdings (up by 4.95Mn shares quarter on quarter which is up 24.06Mn shares year over year).
With 8.76Mn shares, RTW INVESTMENTS, LP commands the largest institutional position in COMPASS Pathways as of December 31, 2025, equating to 9.16% of the company.
Among the most significant buyers of COMPASS Pathways during December 2025 were TORONTO DOMINION BANK (1.53Mn), Siren, L.L.C. (1.00Mn), Point72 Asset Management, L.P. (844.82K), Kalehua Capital Management LLC (819.69K), D. E. Shaw & Co., Inc. (775.08K).
Leading sellers of COMPASS Pathways stock in December 2025 included MILLENNIUM MANAGEMENT LLC (1.33Mn), Nantahala Capital Management, LLC (1.29Mn), PFM Health Sciences, LP (883.22K), DLD Asset Management, LP (586.00K), AMERIPRISE FINANCIAL INC (563.72K).
The top 10 institutional holders of COMPASS Pathways for the quarter ending December 2025 included RTW INVESTMENTS, LP (8.76Mn), Deep Track Capital, LP (7.33Mn), GMT CAPITAL CORP (2.84Mn), TORONTO DOMINION BANK (2.53Mn), ARK Investment Management LLC (2.16Mn), UBS Group AG (2.04Mn), TWO SIGMA INVESTMENTS, LP (1.64Mn), Jefferies Financial Group Inc. (1.58Mn), Eagle Health Investments LP (1.52Mn), D. E. Shaw & Co., Inc. (1.45Mn).

157 Institutional Holders

7,243,433 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
RTW INVESTMENTS, LP	31 Dec, 2025	8,757,390	50,000	0.57%	$60,425,991.00
Deep Track Capital, LP	31 Dec, 2025	7,334,323	-525,325	-6.68%	$50,606,829.00
GMT CAPITAL CORP	31 Dec, 2025	2,844,618	0	0.00%	$19,627,864.00
TORONTO DOMINION BANK	31 Dec, 2025	2,529,013	1,529,013	152.90%	$17,446,594.00
ARK Investment Management LLC	31 Dec, 2025	2,156,012	34,894	1.65%	$14,876,481.00
UBS Group AG	31 Dec, 2025	2,038,444	-105,966	-4.94%	$14,065,263.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	1,644,242	568,965	52.91%	$11,345,270.00
Jefferies Financial Group Inc.	31 Dec, 2025	1,576,905	200,000	14.53%	$10,880,645.00
Eagle Health Investments LP	31 Dec, 2025	1,519,388	583,938	62.42%	$10,483,777.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	1,453,876	775,084	114.19%	$10,031,744.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	1,387,658	-1,328,214	-48.91%	$9,574,840.00
Aisling Capital Management LP	31 Dec, 2025	1,198,418	0	0.00%	$8,269,084.00
MORGAN STANLEY	31 Dec, 2025	1,137,520	107,215	10.41%	$7,848,890.00
Siren, L.L.C.	31 Dec, 2025	1,000,000	1,000,000	0.00%	$6,900,000.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	967,846	16,646	1.75%	$6,678,137.00
Propel Bio Management, LLC	31 Dec, 2025	861,778	351,778	68.98%	$5,946,268.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	856,500	308,000	56.15%	$5,909,850.00
Point72 Asset Management, L.P.	31 Dec, 2025	844,816	844,816	0.00%	$5,829,230.00
Kalehua Capital Management LLC	31 Dec, 2025	819,692	819,692	0.00%	$5,655,875.00
DAFNA Capital Management LLC	31 Dec, 2025	811,046	0	0.00%	$5,596,217.00

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