NuCana (NCNA) Research & Development (2017 - 2025)

NuCana (NCNA) reported Research & Development of -$2.3 million for Q4 2025, down 146.79% on a YoY basis from $4.9 million in Q4 2024, and up 21.21% sequentially from -$2.9 million in Q3 2025.

NuCana (NCNA) Research & Development (2017 - 2025) Analysis & Trends

NuCana (NCNA) has 9 years of Research & Development data on file, last reported at -$2.3 million in Q4 2025.

  • For the quarter ending Q4 2025, Research & Development fell 146.79% year-over-year to -$2.3 million; the trailing twelve-month figure through Dec 2025 stood at -$16.9 million (up 26.37% YoY), and the FY2025 full-year result was -$16.8 million, up 27.08% from the prior year.
  • Research & Development grew to -$2.3 million in Q4 2025, from -$2.9 million in the prior quarter.
  • In the past five years, Research & Development ranged from a high of $11.9 million in Q2 2021 to a low of -$15.5 million in Q4 2022.
  • A 5-year average of -$6.3 million and a median of -$8.5 million in 2023 frame the typical range for Research & Development.
  • Peak annual rise in Research & Development reached 263.64% in 2021, while the deepest fall reached 257.72% in 2021.
  • Tracing NCNA's Research & Development over 5 years: stood at -$14.3 million in 2021, then declined by 7.91% to -$15.5 million in 2022, then surged by 44.97% to -$8.5 million in 2023, then soared by 89.01% to -$935672.8 in 2024, then plunged by 146.79% to -$2.3 million in 2025.
  • Business Quant data shows NCNA's Research & Development at -$2.3 million in Q4 2025, -$2.9 million in Q3 2025, and -$9.5 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -17.94 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 1.46 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 541.22 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 961.60 Mn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 1.54 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 15.66 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -443.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 343.97 Mn
10 NuCana 14.60 Bn 14.60 Bn - -2.31 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -2.31 Mn
Sep 30, 2025 -2.93 Mn
Jun 30, 2025 -9.48 Mn
Mar 31, 2025 -2.17 Mn
Dec 31, 2024 -935,672.84
Sep 30, 2024 -4.85 Mn
Jun 30, 2024 -8.54 Mn
Mar 31, 2024 -8.60 Mn
Dec 31, 2023 -8.51 Mn
Sep 30, 2023 -9.42 Mn
Jun 30, 2023 -4.95 Mn
Mar 31, 2023 -8.27 Mn
Dec 31, 2022 -15.47 Mn
Sep 30, 2022 -8.70 Mn
Jun 30, 2022 8.07 Mn
Mar 31, 2022 -12.67 Mn
Dec 31, 2021 -14.33 Mn
Sep 30, 2021 -12.37 Mn
Jun 30, 2021 11.91 Mn
Mar 31, 2021 -12.00 Mn