NuCana (NCNA) Research & Development (2017 - 2025)

NuCana's (NCNA) quarterly Research & Development came in at -$2.3 million in Q4 2025, down 146.79% year-on-year from $4.9 million in Q4 2024, and up 21.21% quarter-over-quarter from -$2.9 million in Q3 2025.

NuCana (NCNA) Research & Development (2017 - 2025) Analysis & Trends

NuCana has disclosed Research & Development across 9 years of filings, most recently posting -$2.3 million for Q4 2025.

  • Research & Development for Q4 2025 came in at -$2.3 million, down 146.79% year-over-year; the trailing twelve-month figure through Dec 2025 was $2.1 million (up 135.29% YoY), and the FY2025 annual result was -$16.8 million, up 27.08% from the prior year.
  • Research & Development came in at -$2.3 million for Q4 2025 at NuCana, up from -$2.9 million in the prior quarter.
  • In the past five years, Research & Development ranged from a high of $11.9 million in Q2 2021 to a low of -$15.5 million in Q4 2022.
  • The 5-year median for Research & Development is -$6.6 million (2023), against an average of -$4.0 million.
  • Peak annual rise in Research & Development reached 263.64% in 2021, while the deepest fall reached 257.72% in 2021.
  • NuCana's Research & Development stood at -$14.3 million in 2021, then fell by 7.91% to -$15.5 million in 2022, then soared by 44.97% to -$8.5 million in 2023, then jumped by 89.01% to -$935672.8 in 2024, then tumbled by 146.79% to -$2.3 million in 2025.
  • The last three Research & Development figures came in at -$2.3 million (Q4 2025), -$2.9 million (Q3 2025), and $9.5 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Alterity Therapeutics 723,416.35 Bn 723,416.32 Bn - 4.32 Mn
2 Belite Bio 57,340.00 Bn 57,340.00 Bn - 15.66 Mn
3 Quantum Biopharma 19,125.08 Bn 19,125.08 Bn - 626,092.00
4 Legend Biotech 3,262.00 Bn 3,261.71 Bn 242.10 Mn -101.30 Mn
5 Akari Therapeutics 1,789.67 Bn 1,789.67 Bn - 1.46 Mn
6 Evaxion A 1,480.39 Bn 1,480.37 Bn - -2.30 Mn
7 Psyence Biomedical 241.78 Bn 241.78 Bn - 357,444.00
8 Vertex Pharmaceuticals 113.54 Bn 106.29 Bn 2.59 Bn 961.60 Mn
9 Abivax 94.26 Bn 94.26 Bn - -58.00 Mn
10 NuCana 29.13 Bn 29.13 Bn - -2.31 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -2.31 Mn
Sep 30, 2025 -2.93 Mn
Jun 30, 2025 9.48 Mn
Mar 31, 2025 -2.17 Mn
Dec 31, 2024 -935,672.84
Sep 30, 2024 -4.85 Mn
Jun 30, 2024 8.54 Mn
Mar 31, 2024 -8.60 Mn
Dec 31, 2023 -8.51 Mn
Sep 30, 2023 -9.42 Mn
Jun 30, 2023 4.95 Mn
Mar 31, 2023 -8.27 Mn
Dec 31, 2022 -15.47 Mn
Sep 30, 2022 -8.70 Mn
Jun 30, 2022 8.07 Mn
Mar 31, 2022 -12.67 Mn
Dec 31, 2021 -14.33 Mn
Sep 30, 2021 -12.37 Mn
Jun 30, 2021 11.91 Mn
Mar 31, 2021 -12.00 Mn