NuCana (NCNA) Profit After Tax (2017 - 2025)

NuCana's (NCNA) quarterly Profit After Tax came in at -$3.3 million in Q4 2025, down 294.39% year-on-year from $1.7 million in Q4 2024, and down 771.76% quarter-over-quarter from -$379170.8 in Q3 2025.

NuCana (NCNA) Profit After Tax (2017 - 2025) Analysis & Trends

NuCana has disclosed Profit After Tax across 9 years of filings, most recently posting -$3.3 million for Q4 2025.

  • Profit After Tax for Q4 2025 came in at -$3.3 million, down 294.39% year-over-year; the trailing twelve-month figure through Dec 2025 was $25.4 million (up 487.67% YoY), and the FY2025 annual result was -$38.7 million, down 59.38% from the prior year.
  • Profit After Tax came in at -$3.3 million for Q4 2025 at NuCana, down from -$379170.8 in the prior quarter.
  • In the past five years, Profit After Tax ranged from a high of $32.2 million in Q2 2025 to a low of -$18.4 million in Q4 2021.
  • The 5-year median for Profit After Tax is -$5.6 million (2022), against an average of -$3.1 million.
  • Peak annual rise in Profit After Tax reached 268.77% in 2021, while the deepest fall reached 364.75% in 2021.
  • NuCana's Profit After Tax stood at -$18.4 million in 2021, then gained by 3.07% to -$17.8 million in 2022, then soared by 46.71% to -$9.5 million in 2023, then surged by 91.18% to -$838126.7 in 2024, then plunged by 294.39% to -$3.3 million in 2025.
  • The last three Profit After Tax figures came in at -$3.3 million (Q4 2025), -$379170.8 (Q3 2025), and $32.2 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Alterity Therapeutics 723,416.35 Bn 723,416.32 Bn - -
2 Belite Bio 57,340.00 Bn 57,340.00 Bn - -26.94 Mn
3 Quantum Biopharma 19,125.08 Bn 19,125.08 Bn - -2.97 Mn
4 Legend Biotech 3,262.00 Bn 3,261.71 Bn 242.10 Mn 30.90 Mn
5 Akari Therapeutics 1,789.67 Bn 1,789.67 Bn - -14.46 Mn
6 Evaxion A 1,480.39 Bn 1,480.37 Bn - -3.63 Mn
7 Psyence Biomedical 241.78 Bn 241.78 Bn - -753,254.00
8 Vertex Pharmaceuticals 113.54 Bn 106.29 Bn 2.59 Bn 1.03 Bn
9 Abivax 94.26 Bn 94.26 Bn - -56.74 Mn
10 NuCana 29.13 Bn 29.13 Bn - -3.31 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -3.31 Mn
Sep 30, 2025 -379,170.76
Jun 30, 2025 32.17 Mn
Mar 31, 2025 -3.11 Mn
Dec 31, 2024 -838,126.70
Sep 30, 2024 -5.86 Mn
Jun 30, 2024 8.83 Mn
Mar 31, 2024 -8.67 Mn
Dec 31, 2023 -9.50 Mn
Sep 30, 2023 -8.48 Mn
Jun 30, 2023 6.77 Mn
Mar 31, 2023 -9.56 Mn
Dec 31, 2022 -17.83 Mn
Sep 30, 2022 -5.34 Mn
Jun 30, 2022 4.90 Mn
Mar 31, 2022 -11.28 Mn
Dec 31, 2021 -18.39 Mn
Sep 30, 2021 -11.09 Mn
Jun 30, 2021 12.70 Mn
Mar 31, 2021 -13.46 Mn