NuCana (NCNA) EBT (2017 - 2025)

NuCana (NCNA) reported EBT of -$3.5 million for Q4 2025, down 244.62% on a YoY basis from $2.4 million in Q4 2024, and down 313.68% sequentially from -$844700.7 in Q3 2025.

NuCana (NCNA) EBT (2017 - 2025) Analysis & Trends

NuCana (NCNA) has 9 years of EBT data on file, last reported at -$3.5 million in Q4 2025.

  • For the quarter ending Q4 2025, EBT fell 244.62% year-over-year to -$3.5 million; the trailing twelve-month figure through Dec 2025 stood at -$40.5 million (down 41.62% YoY), and the FY2025 full-year result was -$40.2 million, down 40.22% from the prior year.
  • EBT retreated to -$3.5 million in Q4 2025, from -$844700.7 in the prior quarter.
  • In the past five years, EBT ranged from a high of -$844700.7 in Q3 2025 to a low of -$32.6 million in Q2 2025.
  • A 5-year average of -$11.1 million and a median of -$10.4 million in 2024 frame the typical range for EBT.
  • Across the five-year window, EBT surged 90.89% in 2024 and tumbled 244.62% in 2025, its largest moves.
  • Tracing NCNA's EBT over 5 years: stood at -$21.2 million in 2021, then advanced by 6.1% to -$19.9 million in 2022, then jumped by 44.03% to -$11.1 million in 2023, then surged by 90.89% to -$1.0 million in 2024, then plunged by 244.62% to -$3.5 million in 2025.
  • Business Quant data shows NCNA's EBT at -$3.5 million in Q4 2025, -$844700.7 in Q3 2025, and -$32.6 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -36.97 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.31 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 259.22 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.25 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 831.20 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -26.94 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 438.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -453.82 Mn
10 NuCana 14.60 Bn 14.60 Bn - -3.49 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -3.49 Mn
Sep 30, 2025 -844,700.70
Jun 30, 2025 -32.61 Mn
Mar 31, 2025 -3.56 Mn
Dec 31, 2024 -1.01 Mn
Sep 30, 2024 -6.82 Mn
Jun 30, 2024 -10.43 Mn
Mar 31, 2024 -10.33 Mn
Dec 31, 2023 -11.13 Mn
Sep 30, 2023 -10.26 Mn
Jun 30, 2023 -7.63 Mn
Mar 31, 2023 -10.77 Mn
Dec 31, 2022 -19.89 Mn
Sep 30, 2022 -7.04 Mn
Jun 30, 2022 -6.40 Mn
Mar 31, 2022 -14.00 Mn
Dec 31, 2021 -21.18 Mn
Sep 30, 2021 -13.72 Mn
Jun 30, 2021 -14.92 Mn
Mar 31, 2021 -15.81 Mn