NuCana (NCNA) EBIT (2017 - 2025)
NuCana's (NCNA) quarterly EBIT came in at -$3.7 million in Q4 2025, down 235.47% year-on-year from $2.7 million in Q4 2024, and down 254.32% quarter-over-quarter from -$1.1 million in Q3 2025.
NuCana (NCNA) EBIT (2017 - 2025) Analysis & Trends
NuCana has disclosed EBIT across 9 years of filings, most recently posting -$3.7 million for Q4 2025.
- EBIT for Q4 2025 came in at -$3.7 million, down 235.47% year-over-year; the trailing twelve-month figure through Dec 2025 was -$24.1 million (up 16.9% YoY), and the FY2025 annual result was -$26.5 million, up 9.06% from the prior year.
- EBIT came in at -$3.7 million for Q4 2025 at NuCana, down from -$1.1 million in the prior quarter.
- In the past five years, EBIT ranged from a high of -$1.1 million in Q3 2025 to a low of -$21.2 million in Q4 2021.
- The 5-year median for EBIT is -$10.5 million (2024), against an average of -$10.4 million.
- Across the five-year window, EBIT jumped 90.18% in 2024 and plunged 235.47% in 2025, its largest moves.
- NuCana's EBIT stood at -$21.2 million in 2021, then increased by 4.63% to -$20.2 million in 2022, then jumped by 44.13% to -$11.3 million in 2023, then surged by 90.18% to -$1.1 million in 2024, then slumped by 235.47% to -$3.7 million in 2025.
- The last three EBIT figures came in at -$3.7 million (Q4 2025), -$1.1 million (Q3 2025), and -$15.8 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 723,416.35 Bn | 723,416.32 Bn | - | - |
| 2 | Belite Bio | 57,340.00 Bn | 57,340.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 19,125.08 Bn | 19,125.08 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 3,262.00 Bn | 3,261.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,789.67 Bn | 1,789.67 Bn | - | -15.76 Mn |
| 6 | Evaxion A | 1,480.39 Bn | 1,480.37 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 241.78 Bn | 241.78 Bn | - | -1.51 Mn |
| 8 | Vertex Pharmaceuticals | 113.54 Bn | 106.29 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 94.26 Bn | 94.26 Bn | - | -65.83 Mn |
| 10 | NuCana | 29.13 Bn | 29.13 Bn | - | -3.72 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -3.72 Mn |
| Sep 30, 2025 | -1.05 Mn |
| Jun 30, 2025 | -15.78 Mn |
| Mar 31, 2025 | -3.59 Mn |
| Dec 31, 2024 | -1.11 Mn |
| Sep 30, 2024 | -6.92 Mn |
| Jun 30, 2024 | -10.54 Mn |
| Mar 31, 2024 | -10.49 Mn |
| Dec 31, 2023 | -11.30 Mn |
| Sep 30, 2023 | -10.45 Mn |
| Jun 30, 2023 | -7.85 Mn |
| Mar 31, 2023 | -11.12 Mn |
| Dec 31, 2022 | -20.23 Mn |
| Sep 30, 2022 | -7.29 Mn |
| Jun 30, 2022 | -6.57 Mn |
| Mar 31, 2022 | -14.04 Mn |
| Dec 31, 2021 | -21.21 Mn |
| Sep 30, 2021 | -13.75 Mn |
| Jun 30, 2021 | -14.97 Mn |
| Mar 31, 2021 | -15.84 Mn |